Thin films flowing down inverted substrates: Three dimensional flow

We study contact line induced instabilities for a thin film of fluid under destabilizing gravitational force in three dimensional setting. In the previous work (Phys. Fluids, {\bf 22}, 052105 (2010)), we considered two dimensional flow, finding formation of surface waves whose properties within the implemented long wave model depend on a single parameter, $D=(3Ca)^{1/3}\cot\alpha$, where $Ca$ is the capillary number and $\alpha$ is the inclination angle. In the present work we consider fully 3D setting and discuss the influence of the additional dimension on stability properties of the flow. In particular, we concentrate on the coupling between the surface instability and the transverse (fingering) instabilities of the film front. We furthermore consider these instabilities in the setting where fluid viscosity varies in the transverse direction. It is found that the flow pattern strongly depends on the inclination angle and the viscosity gradient

Annihilation of vortex dipoles in an Oblate Bose-Einstein Condensate

We theoretically explore the annihilation of vortex dipoles, generated when an obstacle moves through an oblate Bose-Einstein condensate, and examine the energetics of the annihilation event. We show that the gray soliton, which results from the vortex dipole annihilation, is lower in energy than the vortex dipole. We also investigate the annihilation events numerically and observe that the annihilation occurs only when the vortex dipole overtakes the obstacle and comes closer than the coherence length. Furthermore, we find that the noise reduces the probability of annihilation events. This may explain the lack of annihilation events in experimental realizations.Comment: 8 pages and 9 figure

The Modified Weighted Slab Technique: Models and Results

In an attempt to understand the source and propagation of galactic cosmic rays we have employed the Modified Weighted Slab technique along with recent values of the relevant cross sections to compute primary to secondary ratios including B/C and Sub-Fe/Fe for different galactic propagation models. The models that we have considered are the disk-halo diffusion model, the dynamical halo wind model, the turbulent diffusion model and a model with minimal reacceleration. The modified weighted slab technique will be briefly discussed and a more detailed description of the models will be given. We will also discuss the impact that the various models have on the problem of anisotropy at high energy and discuss what properties of a particular model bear on this issue.Comment: LaTeX - AASTEX format, Submitted to ApJ, 8 figures, 20 page

ИССЛЕДОВАНИЯ ОБЪЕКТОВ КУЛЬТУРНОГО НАСЛЕДИЯ ФЕДЕРОЛЬНОГО ЗНАЧЕНИЯ

This article is supposed to make a professional analysis and assess the reliability of the historical buildings in Ryazan - an object of cultural heritage of federal importance “House of Saltykov-Shchedrin (Morozov) - 18th century”. On the basis of visual inspection and a large number of field studies using methods of ground-based laser scanning, photogrammetric method and other measuring instruments, areas of destruction and loss of the building were identified. According to the results of the analysis of archival documents and the processing of field work, a complex of architectural and archaeological measurement drawings was drawn up, on the basis of which further house restoration will be carried out without any damage to historical material. The article on a specific example provides brief archival information about the historical significance of the building, describes the methods and methods of the survey.Se supone que este artículo hace un análisis profesional y evalúa la confiabilidad de los edificios históricos en Ryazan, un objeto del patrimonio cultural de importancia federal "Casa de Saltykov-Shchedrin (Morozov) - Siglo XVIII". Sobre la base de la inspección visual y un gran número de estudios de campo que utilizan métodos de escaneo láser en tierra, el método fotogramétrico y otros instrumentos de medición, se identificaron áreas de destrucción y pérdida del edificio. De acuerdo con los resultados del análisis de documentos de archivo y el procesamiento del trabajo de campo, se diseñó un complejo de planos de mediciones arquitectónicas y arqueológicas, sobre la base de la cual se llevará a cabo una restauración adicional de la casa sin dañar el material histórico. El artículo sobre un ejemplo específico proporciona información breve de archivo sobre el significado histórico del edificio, describe los métodos y los métodos de la encuesta.В данной статье предполагается сделать профессиональный анализ и оценить надежность здания исторической застройки г. Рязани – объект культурного наследия федерального значения «Дом Салтыкова-Щедрина (Морозова)-XVIII в.». На основе визуального обследования и большого количества натурных исследований методами наземного лазерного сканирования, фотограмметрическим методом и другими измерительными приборами было выявлены участки разрушений и утраты здания. По результатам анализа архивных документов и обработки полевых работ стал комплекс архитектурно-археологических обмерных чертежей, на основе которого будет дальнейшая реставрация дома без какого-либо ущерба историческому материалу. В статье на конкретном примере приводятся краткие архивные сведения об исторической значимости здания, описаны методы и способы обследования

GASTROESOPHAGEAL REFLUX DISEASE IN PATIENTS WITH FUNCTIONAL DYSPEPSIA AND CONSTIPATION PREDOMINANT IRRITABLE BOWEL SYNDROME: CLINICAL FEATURES AND EFFICACY OF LACTULOSE AND ITOPRIDE HYDROCHLORIDE

Background: The frequent coexistence of gastroesophageal reflux disease (GERD) with functional dyspepsia (FD) and an irritable bowel syndrome (IBS) has been described in the literature. Aim: To study the specific features of GERD clinical course and diagnosis in patients with GERD in combination with FD and constipation predominant IBS (IBS-C) in comparison to patients with isolated GERD; to assess the efficacy of lactulose and itopride hydrochloride. Materials and methods: A total of 60 patients with GERD, FD (Rome criteria III), and IBS-C (Rome criteria III) and 29 patients with isolated GERD were examined. GERD diagnosis was based on clinical, endoscopic, and pH-metric criteria. For 4 weeks 10 patients with combination of non-erosive reflux disease (NERD), FD and IBS-C received lactulose monotherapy and other 10 patients received combination of lactulose with itopride hydrochloride. Clinical symptoms and pH-metric parameters were assessed before and 4 weeks after treatment. Results: Combination of GERD, FD and IBS-C was noted more frequently in women under 40 with normal body mass index (р<0.05). Classic GERD symptoms were absent in 43.4% of patients with gastrointestinal comorbidity and in 10.3% of patients with isolated GERD (р=0.004). A higher prevalence of belching and nausea was found in patients, suffering from GERD, FD and IBS-C, than in those with isolated GERD (р<0.05). After 4-week lactulose and itopride hydrochloride treatment all the patients with GERD, FD and IBS-C showed a reduction of clinical symptoms (p<0.05) and normalization of pH-metric parameters (р<0.001). Conclusion: GERD course in patients with concomitant FD and IBS-C has the following peculiarities: predominance of women, absence of classic GERD-symptoms in almost half of these patients, and frequent combination with other functional symptoms. Combination therapy with lactulose and itopride hydrochloride enables successful control of GERD and FD symptoms as well as esophageal pH normalization

Gender and age structure of mortality caused by COVID-19

Introduction: The policy of mortality decline of the population of Russia, pursued by the state, requires consideration of the regional peculiarities of mortality in territorial subjects of the Russian Federation by gender and age. The regional situation on male and female mortality also should be considered when developing the measures directed to prevent various diseases including infectious ones. In this regard, the studies of gender and age indicators of mortality during the periods of infectious pandemics become relevant.Objective: The analysis of gender and age rates of COVID-19 mortality in 2021 in order to substantiate the best management decisions in the sphere of the organization of medical care and statistical registration of lethal outcomes during the pandemic spread of dangerous viral infections.Material and methods: The main source of information on mortality in 2020 is data of the State Statistics of Mortality of Rosstat. The data on mortality in 2021 are presented in the records on death cases in Federal State Information System “Unified State Register of Registration of Acts of Current State”. To evaluate the obtained data, simple (unweighted) arithmetic mean values, specific indicators, a root mean square (standard) deviation of the mean values, coefficient of variation were used (a measure of the spread of attribute values – the ratio of a standard deviation to the arithmetic-mean).Results: In 2021 17.3% of total number of all deaths had COVID-19 as an initial cause of death. 248,134 cases of those were women (58.5%), 176,116 cases were men (41.5%). The mortality rate from COVID-19 increased by an average 1.7 times upon transition from one five-year-old age group to another, 85% of those who died from COVID-19 were aged 60 years and older. In 2021 the coronavirus infection of COVID-19 contributed significantly to female mortality more, than male mortality, which is inconsistent with the data on gender structure of COVID-19 mortality in other countries, as well as with the widespread belief that men are more vulnerable to this infection.Conclusions: Growth rates of COVID-19 mortality depending on age resembles the aging rate, reflecting the biological nature of mortality. Total excess mortality is the better basis for assessment of changes in the population health during pandemics, than mortality from COVID-19 alone. The organization of systematic checks of correctness of coding the causes of death at the state registration of death is necessary.Restrictions: Data of the Federal State Information System “Unified State Register of Registration of Acts of Current State” can differ from data of Rosstat which in 2022 became available to professional researchers later, than data of the Federal State Information System “Unified State Register of Registration of Acts of Current State”

Three-dimensional localized coherent structures of surface turbulence. III Experiment and model validation

The paper continues a series of publications devoted to the 3D nonlinear localized coherent structures on the surface of vertically falling liquid films. The work is primarily focussed on experimental investigations. We study: (i) instabilities and transitions leading to 3D coherent structures; (ii) characteristics of these structures. Some nonstationary effects are also studied numerically. Our experimental results, as well as the results of other investigators, are in a good agreement with our theoretical and numerical predictions.Comment: 42 pages, 15 figure

Dynamics of Vortex Pair in Radial Flow

The problem of vortex pair motion in two-dimensional plane radial flow is solved. Under certain conditions for flow parameters, the vortex pair can reverse its motion within a bounded region. The vortex-pair translational velocity decreases or increases after passing through the source/sink region, depending on whether the flow is diverging or converging, respectively. The rotational motion of two corotating vortexes in a quiescent environment transforms into motion along a logarithmic spiral in the presence of radial flow. The problem may have applications in astrophysics and geophysics.Comment: 13 pages, 9 figure