Phonon transport in large scale carbon-based disordered materials: Implementation of an efficient order-N and real-space Kubo methodology

We have developed an efficient order-N real-space Kubo approach for the calculation of the phonon conductivity which outperforms state-of-the-art alternative implementations based on the Green's function formalism. The method treats efficiently the time-dependent propagation of phonon wave packets in real space, and this dynamics is related to the calculation of the thermal conductance. Without loss of generality, we validate the accuracy of the method by comparing the calculated phonon mean free paths in disordered carbon nanotubes (isotope impurities) with other approaches, and further illustrate its upscalability by exploring the thermal conductance features in large width edge-disordered graphene nanoribbons (up to ~20 nm), which is out of the reach of more conventional techniques. We show that edge-disorder is the most important scattering mechanism for phonons in graphene nanoribbons with realistic sizes and thermal conductance can be reduced by a factor of ~10.Comment: Accepted for publication in Physical Review B - Rapid Communication

Extracting and re-using research data from chemistry e-theses: the SPECTRa-T project

Scientific e-theses are data-rich resources, but much of the information they contain is not readily accessible. For chemistry, the SPECTRa-T project has addressed this problem by developing data-mining techniques to extract experimental data, creating RDF (Resource Description Framework) triples for exposure to sophisticated Semantic Web searches. We used OSCAR3, an Open Source chemistry text-mining tool, to parse and extract data from theses in PDF, and from theses in Office Open XML document format. Theses in PDF suffered data corruption and a loss of formatting that prevented the identification of chemical objects. Theses in .docx yielded semantically rich SciXML that enabled the additional extraction of associated data. Chemical objects were placed in a data repository, and RDF triples deposited in a triplestore. Data-mining from chemistry e-theses is both desirable and feasible; but the use of PDF, the de facto format standard for deposit in most repositories, prevents the optimal extraction of data for semantic querying. In order to facilitate this, we recommend that universities also require deposition of chemistry e-theses in an XML document format. Further work is required to clarify the complex IPR issues and ensure that they do not become an unwarranted barrier to data extraction and re-use

Group-Based Parent Training Interventions for Parents of Children with Autism Spectrum Disorders: a Literature Review

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Parents of children with autism spectrum disorders should have access to interventions to help them understand and support their child. This literature review examines the existing evidence for group-based parent training interventions that support parents of children with autism. From the literature, core intervention processes and outcomes are identified and include parenting and parent behaviour, parent health, child behaviour and peer and social support. Results show a positive trend for intervention effectiveness, but findings are limited by low-quality studies and heterogeneity of intervention content, outcomes and outcome measurement. Future research should focus on specifying effective intervention ingredients and modes of delivery, consistent and reliable outcome measurement, and improving methodological rigour to build a more robust evidence base

A global simulation for laser driven MeV electrons in 50μm50\mu m-diameter fast ignition targets

The results from 2.5-dimensional Particle-in-Cell simulations for the interaction of a picosecond-long ignition laser pulse with a plasma pellet of 50-$\mu m$ diameter and 40 critical density are presented. The high density pellet is surrounded by an underdense corona and is isolated by a vacuum region from the simulation box boundary. The laser pulse is shown to filament and create density channels on the laser-plasma interface. The density channels increase the laser absorption efficiency and help generate an energetic electron distribution with a large angular spread. The combined distribution of the forward-going energetic electrons and the induced return electrons is marginally unstable to the current filament instability. The ions play an important role in neutralizing the space charges induced by the the temperature disparity between different electron groups. No global coalescing of the current filaments resulted from the instability is observed, consistent with the observed large angular spread of the energetic electrons.Comment: 9 pages, 6 figures, to appear in Physics of Plasmas (May 2006

Validating 3D two-parameter fracture mechanics models for structural integrity assessments

In-situ fracture tests were carried out on the I12 beamline at the Diamond Light Source. Four Al-Ti metal-matrix composites (MMCs), with two crack lengths, were studied to assess for the impact of in-plane constraint. Synchrotron X-ray computed tomography and synchrotron X-ray diffraction were used to measure total strain and elastic strain respectively. In this work, the measured elastic strains in the samples are detailed as a function of applied load and compared against those predicted from a 3D elastic-plastic finite element model. The modelled strains increased asymptotically towards the tip of the electro discharge machined notch. The experimental results do not highlight the same response, which is due to a combination of blunting and low experimental spatial resolution. Far field experimental and measured strain fields converged, notably in the test piece containing a long notch (a/W = 0.5) and higher levels of constraint

DESIGNING AND TESTING A PARK-BASED VISITOR SURVEY

This technical report is part of a broader national project ‘Systematic and strategic collection and use of visitor information in protected area management’, funded by Sustainable Tourism Cooperative Research Centre (STCRC), and conducted in partnership with protected area agencies across Australia. The aim of this report is to provide a systematic approach to using a set of core variables to collect data in a way that can be consistently applied across Australian protected areas. This information is most relevant to park-level management, but is also of central interest for corporate reporting. An associated aim was to develop and test a questionnaire for collecting these data. The questionnaire was developed and tested in collaboration with the WA Department of Environment and Conservation (WA DEC) and Parks Australia (PA). Surveys were conducted in Yanchep National Park, a moderately sized peri-urban park managed by WA DEC, in April 2008 and in Booderee National Park, NSW, which encompasses marine features and a botanic garden, and is managed by Parks Australia (PA), in January 2009. In WA following the survey, a focus group was held with staff to obtain their feedback on the efficacy of the questionnaire. The following recommendations are based on statistical analyses of the results, feedback from the focus group, and the observations of the researchers conducting the surveys

Social and community inclusion outcomes for adults with autism with and without intellectual disability in Australia

Background: Research suggests that adults with autism tend to have poor outcomes. Outcomes have mostly been defined using summary outcome ratings, with less focus on specific outcomes such as employment, living situation, social satisfaction, loneliness, and friendships. This study aimed to explore social and community outcomes, including employment, education, living arrangements, friendships, and social satisfaction, for autistic adults with and without intellectual disability. Method: Eighty-four adults with autism (mean age 34.2 years, SD = 4.5; 67% with co-occurring intellectual disability), recruited as children and adolescents, participated in the current study. Adult social and community inclusion outcomes were explored through interview and questionnaire, both parent/carer-report and self-report. Results: Participants predominantly lived with family or in supported accommodation, did not pursue higher education, and mostly participated in day activity programmes. Most had limited friendships as reported by parents/carers; however, self-report data (n = 28) indicated that adults were largely satisfied with their social relationships. Overall outcome was poor for 57%, and good/very good for 34%. Adults with intellectual disability generally had poorer outcomes. Conclusion: Autistic adults encountered numerous difficulties in leading an independent life. Adults with co-occurring intellectual disability were most likely to experience difficulties; however, outcomes ranged from poor to very good for adults without intellectual disability. Discrepancies in parent/carer-report and self-reported experiences of friendships highlight the need to ensure individual experiences are captured in addition to parent/carer-report. Appropriate resources and programmes are crucial for adults with autism to support them to have the choice to live independently.</p

Large-scale trials of a real-time acoustic backscatter system for solids concentration measurement during nuclear waste cleanup

Real time in situ characterisation of solids concentration would aid operational understanding and improve efficiency in many industrial systems. This is especially true in the processing of legacy nuclear wastes where hazardous material is encountered. Acoustic methods have been previously demonstrated for the measurement of concentration in solid-liquid systems at a small scale. This study explores the use of the ultrasound array research platform (UARP) for backscatter measurements of concentration at a large scale in a dynamic settling system. The theory of acoustic measurement of solids concentration is described for both backscatter based attenuation and backscatter power methods. Acoustic based backscatter power and attenuation measurements are compared to laboratory analysed samples. Ultrasonic solids concentration analysis is shown to reveal flow dynamics within the settling tank

Noninvasive Determination of 2-[18F]-Fluoroisonicotinic Acid Hydrazide Pharmacokinetics by Positron Emission Tomography in Mycobacterium tuberculosis-Infected Mice

Tuberculosis (TB) is a global pandemic requiring sustained therapy to facilitate curing and to prevent the emergence of drug resistance. There are few adequate tools to evaluate drug dynamics within infected tissues in vivo. In this report, we evaluated a fluorinated analog of isoniazid (INH), 2-[18F]fluoroisonicotinic acid hydrazide (2-[18F]-INH), as a probe for imaging Mycobacterium tuberculosis-infected mice by dynamic positron emission tomography (PET). We developed a tail vein catheter system to safely deliver drugs to M. tuberculosis aerosol-infected mice inside sealed biocontainment devices. Imaging was rapid and noninvasive, and it could simultaneously visualize multiple tissues. Dynamic PET imaging demonstrated that 2-[18F]-INH was extensively distributed and rapidly accumulated at the sites of infection, including necrotic pulmonary TB lesions. Compared to uninfected animals, M. tuberculosis-infected mice had a significantly higher PET signal within the lungs (P 0.85), suggesting that 2-[18F]-INH accumulated at the site of the pulmonary infection. Furthermore, our data indicated that similar to INH, 2-[18F]-INH required specific activation and accumulated within the bacterium. Pathogen-specific metabolism makes positron-emitting INH analogs attractive candidates for development into imaging probes with the potential to both detect bacteria and yield pharmacokinetic data in situ. Since PET imaging is currently used clinically, this approach could be translated from preclinical studies to use in humans.Chemistry and Chemical Biolog