BCS theory of nodal superconductors

This course has a dual purpose. First we review the successes of the weak-coupling BCS theory in describing new classes of superconductors discovered since 1979. They include the heavy-fermion superconductors, high-Tc cuprate superconductors, organic superconductors, Sr2RuO4, etc. Second, we present the quasiclassical approximation introduced by Volovik, which we extend to describe the thermodynamics and the thermal conductivity of the vortex state in nodal superconductors. This approach provides the most powerful tool to identify the symmetry of the energy gap function Delta(k) in these new superconductors.Comment: 31 pages, 33 figure

Unusual fishery of Parapenaeopsis acclivirostris in Tadri area (Karwar)

The occurrence of Oratosquilla nepa and Acetes johni, only for a few days before the beginning of the night fishing for prawns, serves as an indicator of the commencement of the intensive prawn fishery in the Tadri area of Karwar. The Acetes johni forms favourite food item of some fishes, which is related to the appearance of Lepturacanthus savala at Tadri. trawlers. Once P. acclivirostris which is called as young 'Karikadi' landed from 18-20 fathoms depth amounting to as high as 350 kg/boat. The observations provide a clue to the appearance of prawns from south to north at the beginning of the prawn fishery season in the Tadri-Karwar area during November over the years. This may help the fishermen to plan their fishing activities accordingly

Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke.

Stroke is the leading cause of adult disability. Neurogenesis after stroke is associated with repair; however, the mechanisms regulating poststroke neurogenesis and its functional effect remain unclear. Here, we investigate multiple mechanistic routes of induced neurogenesis in the poststroke brain, using both a forelimb overuse manipulation that models a clinical neurorehabilitation paradigm, as well as local manipulation of cellular activity in the peri-infarct cortex. Increased activity in the forelimb peri-infarct cortex via either modulation drives increased subventricular zone (SVZ) progenitor proliferation, migration, and neuronal maturation in peri-infarct cortex. This effect is sensitive to competition from neighboring brain regions. By using orthogonal tract tracing and rabies virus approaches in transgenic SVZ-lineage-tracing mice, SVZ-derived neurons synaptically integrate into the peri-infarct cortex; these effects are enhanced with forelimb overuse. Synaptic transmission from these newborn SVZ-derived neurons is critical for spontaneous recovery after stroke, as tetanus neurotoxin silencing specifically of the SVZ-derived neurons disrupts the formation of these synaptic connections and hinders functional recovery after stroke. SVZ-derived neurogenesis after stroke is activity-dependent, region-specific, and sensitive to modulation, and the synaptic connections formed by these newborn cells are functionally critical for poststroke recovery

Is Patient Data Better Protected in Competitive Healthcare Markets?

We study the effect of hospital market concentration on the quality of patient data protection practices. We use approximately 200 reported data breaches in US hospitals over the period 2006 - 2011 as a measure of the quality of patient data protection practices. We measure market concentration using the Herfindahl-Hirschman Index (HHI) and estimate our models by exploiting cross-sectional HHI variation. Surprisingly, we find that increased competition is associated with a decline in the quality of patient data protection. Our main result indicates that a 100 point increase in HHI is associated with a 5% decline in the average count of data breach incidents. The results are directionally robust to a number of alternate model specifications. To explain our findings, we posit that hospitals in more competitive markets may be inclined to shift resources to more consumer visible activities from the less consumer visible activity of data protection

Clinical Significance of Telomere Length and Associated Proteins in Oral Cancer

Purpose: Telomere shortening is an important event during carcinogenesis. Although studies suggest role of multiple proteins in telomere length regulation, there is dearth of reports in oral cancer which is a leading malignancy in Asian countries especially in India. Thus the present study was carried out to study these mechanisms and explore the pathways involved in telomere—telomerase regulation and identify possible prognostic markers to understand the biology of oral tumors for better treatment approaches. Methods: Telomere length was determined by Southern Hybridisation method, telomeric repeat binding factor (TRF) 1 and 2 expression was detected by Western blot method and telomerase activation by telomeric repeat amplifi cation protocol. Statistical analysis was done using SPSS (Version 10) software. Results: Significant shortening of telomeres was seen in the tumor tissues as compared to normal tissues. Poor prognosis was observed in the patients with higher telomere length in malignant tissue, higher tumor to normal telomere length ratio (T/N TRF LR). Expression of TRF-2 but not TRF-1 protein was signifi cantly higher in the malignant tissues. We also observed telomerase activation in 75 malignant tissues.Conclusions: Our results reveal signifi cant clinical usefulness of telomere length, T/N TRF LR and telomerase activation in the prognosis of oral cancer patients. TRF-2 overexpression in malignant tissues appears to play an important role in telomere length shortening in oral cancer. Abbreviations: TRF—Terminal restriction fragment; TRF-1—telomeric repeat binding factor-1; TRF-2—telomeric repeat binding factor-2; T/N TRF LR—Tumor/ Normal TRF length ratio

Wireless Sensor Network using DRINA

On demand routing protocols give climbable and price effective solutions for transferring packets in mobile spontaneous networks (MANET). A wireless detector network could be a assortment of distributed nodes to watch and additionally to transmit their information from detector network to a sink node. In wireless detector network, detector nodes area unit set close to every different and additionally act with one another through information routing. In wireless detector network, the information routing takes place in non-aggregated manner would force a lot of energy. Energy conservation is that the major issue in wireless detector network. During this work we have a tendency to propose jury-rigged information routing with in-network aggregation formula which may address this energy consumption issue. It uses information aggregation technique and it will be effective in routing. so information aggregation is beneficial for increasing information accuracy, elimination of information redundancy, and reduction of communication load alongside reducing energy consumption

A study of minimally invasive percutaneous plate osteosynthesis for tibial plateau fractures

Background: Fractures of proximal tibia involve a major weight-bearing joint and are serious injuries, which, if not treated well, result in functional impairment. To preserve normal knee function one must strive to maintain joint congruity, preserve the normal mechanical axis, ensure joint stability and restore a full range of motion. This is a formidable task to accomplish, especially in the face of associated medical conditions of the patients.Methods: In our study, 30 cases were selected. Selection of cases were done on the basis of X-rays. Schatzker type I, II, III, IV, V & VI included in study. Criteria for acceptable reduction 1) <5 mm of articular step; 2) <5 mm of articular depression. Each case is referred to one set of tibial plateau fracture, showing distribution of tibia plateau fractures that we treated with MIPPO. Clinical follow-up examination was performed at 4, 6, 10, 12 weeks and 3, 6 months. Clinico-radiological assessment was done at 3 month and grading was done. Patients were evaluated according to grading minimum 3 months after injury.Results: Our study of 30 tibial plateau fractures confirms that the MIPPO technique is an excellent treatment modality in case of tibial plateau fractures. We observed these fractures mainly in age group of 30-40 years, which were involved in road traffic accident. Tibial plateau fractures seen in elder age group were mainly due to abnormal loading patterns on the leg. We have found oblique views very much informative especially for posterolateral or posteromedial displacement, articular depression which helps to plan the position and direction of screws to be used for fixation. Conclusions: In view of the excellent results obtained with this technique, we advocate MIPPO over conventional open reduction and internal fixation technique for tibial plateau fracture fixation

On the fishery of Acetes johni at Karwar and Tadri

The article describes about the fisheryt of Acetes shrimps, Acetes johni during 1986 at Karwar

A case study of the economics of a traditional prawn culture farm in the North Kanara district, Karnataka, India

Economics of a traditional prawn culture farm situated on the northern bank of Badagani river near Haldipur in the North Kanara district, Karnataka, India is studied. The farm extends over 0.78 hectare and has a single wooden sluice gate. Culture of Penaeus indicus, P. Monodon, Metapenaeus monoceros and M. Dobsoni was initiated in January and continued up to may 1979. The traditional practice of trapping and holding was followed in stocking the farm. In all, 375 kg of prawns valued at Rs. 10,470.00 !were harvested of which. 52% comprised P. indicus and P. monodon. A profit of Rs. 7,770.00 was earned by the entrepreneur after meeting expenditure on the farm. An overall review of the economics of prawn culture in the area is given

Dopamine Transporters in Striatum Correlate with Deactivation in the Default Mode Network during Visuospatial Attention

BACKGROUND:Dopamine and dopamine transporters (DAT, which regulate extracellular dopamine in the brain) are implicated in the modulation of attention but their specific roles are not well understood. Here we hypothesized that dopamine modulates attention by facilitation of brain deactivation in the default mode network (DMN). Thus, higher striatal DAT levels, which would result in an enhanced clearance of dopamine and hence weaker dopamine signals, would be associated to lower deactivation in the DMN during an attention task. METHODOLOGY/PRINCIPAL FINDINGS:For this purpose we assessed the relationship between DAT in striatum (measured with positron emission tomography and [(11)C]cocaine used as DAT radiotracer) and brain activation and deactivation during a parametric visual attention task (measured with blood oxygenation level dependent functional magnetic resonance imaging) in healthy controls. We show that DAT availability in caudate and putamen had a negative correlation with deactivation in ventral parietal regions of the DMN (precuneus, BA 7) and a positive correlation with deactivation in a small region in the ventral anterior cingulate gyrus (BA 24/32). With increasing attentional load, DAT in caudate showed a negative correlation with load-related deactivation increases in precuneus. CONCLUSIONS/SIGNIFICANCE:These findings provide evidence that dopamine transporters modulate neural activity in the DMN and anterior cingulate gyrus during visuospatial attention. Our findings suggest that dopamine modulates attention in part by regulating neuronal activity in posterior parietal cortex including precuneus (region involved in alertness) and cingulate gyrus (region deactivated in proportion to emotional interference). These findings suggest that the beneficial effects of stimulant medications (increase dopamine by blocking DAT) in inattention reflect in part their ability to facilitate the deactivation of the DMN