213 research outputs found
A Formalism for Scattering of Complex Composite Structures. 1 Applications to Branched Structures of Asymmetric Sub-Units
We present a formalism for the scattering of an arbitrary linear or acyclic
branched structure build by joining mutually non-interacting arbitrary
functional sub-units. The formalism consists of three equations expressing the
structural scattering in terms of three equations expressing the sub-unit
scattering. The structural scattering expressions allows a composite structures
to be used as sub-units within the formalism itself. This allows the scattering
expressions for complex hierarchical structures to be derived with great ease.
The formalism is furthermore generic in the sense that the scattering due to
structural connectivity is completely decoupled from internal structure of the
sub-units. This allows sub-units to be replaced by more complex structures. We
illustrate the physical interpretation of the formalism diagrammatically. By
applying a self-consistency requirement we derive the pair distributions of an
ideal flexible polymer sub-unit. We illustrate the formalism by deriving
generic scattering expressions for branched structures such as stars, pom-poms,
bottle-brushes, and dendrimers build out of asymmetric two-functional
sub-units.Comment: Complete rewrite generalizing the formalism to arbitrary functional
sub-units and including a new Feynmann like diagrammatic interpretatio
The paranasal sinuses are focus for colonisation and chronic biofilm lung infection in CF patients
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Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015
The plasmid-mediated colistin resistance gene, mcr-1, was detected in an Escherichia coli isolate from a Danish patient with bloodstream infection and in five E. coli isolates from imported chicken meat. One isolate from chicken meat belonged to the epidemic spreading sequence type ST131. In addition to IncI2*, an incX4 replicon was found to be linked to mcr-1. This report follows a recent detection of mcr-1 in E. coli from animals, food and humans in China. </jats:p
Data-driven analysis of <i>JAK2</i> V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms
A phase II study of the vitamin D analogue Seocalcitol in patients with inoperable hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a common malignant tumour, which has a poor prognosis. Surgical resection can be curative but most patients are inoperable and most chemotherapy agents have minimal activity in this disease. Seocalcitol, a vitamin D analogue, induces differentiation and inhibits growth in cancer cell lines and in vivo. The vitamin D receptor is expressed in hepatocytes and more abundantly in HCC cells. In total, 56 patients with inoperable advanced HCC were included in an uncontrolled study of oral Seocalcitol treatment for up to 1 year ( with possible extension for responders). The dose was titrated according to serum calcium levels. The treatment effect was evaluated by regular CT scans. Out of 33 patients evaluable for tumour response, two had complete response (CR), 12 stable disease and 19 progressive disease. The CRs appeared after 6 and 24 months of treatment, and lasted for 29 and at least 36 months ( patient still in remission when data censored). Seocalcitol was well tolerated; the most frequent toxicity was hypercalcaemia and related symptoms. Most patients tolerated a daily dose of 10 mug of Seocalcitol. This is the first study showing activity, by reduction in tumour dimensions, of a differentiating agent in patients with an advanced bulky, solid tumour. Seocalcitol may have an effect in the treatment of HCC, especially in early disease when a prolonged treatment can be instituted. The survival benefit with or without tumour response should be determined in controlled studies
Decay Lengths for Diffusive Transport Activated by Andreev Reflections in Al/n-GaAs/Al Superconductor-Semiconductor-Superconductor Junctions
Coherent diffusive transport mediated by Andreev reflections at V=Delta/e in a mesoscopic superconductor/semiconductor/superconductor junction
Whole-genome sequencing of bloodstream Staphylococcus aureus isolates does not distinguish bacteraemia from endocarditis
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