Energy absorption by polymer crazing

During the past thirty years, a tremendous amount of research was done on the development of crazing in polymers. The phenomenon of crazing was recognized as an unusual deformation behavior associated with a process of molecular orientation in a solid to resist failure. The craze absorbs a fairly large amount of energy during the crazing process. When a craze does occur the surrounding bulk material is usually stretched to several hundred percent of its original dimension and creates a new phase. The total energy absorbed by a craze during the crazing process in creep was calculated analytically with the help of some experimental measurements. A comparison of the energy absorption by the new phase and that by the original bulk uncrazed medium is made

Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs.

Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge. With advances in chemical and enzymatic carbohydrate synthesis, the availability of complex carbohydrates is increasing and developing methods for stereoselective conjugation these polar head groups to proteins and lipids is critically important for pharmaceutical applications. The aim of this review is to provide an overview of commonly employed strategies for installing a functionalized linker at the anomeric position as well as examples of further transformations that have successfully led to glycoconjugation to vaccine constructs for biological evaluation as carbohydrate-based therapeutics

Mechanisms of wave transformation in finite-depth water

Mechanisms of wave transformation in finite-depth water are investigated. The linear mechanisms ex- amined are percolation, bottom motion, shoaling, and refraction. The nonlinear mechanisms examined are wave-wave interaction and bottom friction. New exact computations of the nonlinear transfer for fi- nite-depth waves are presented for some directional wave spectra. These mechanisms are found to ex- plain satisfactorily wave decay observations obtained at several sites with different bottom sediment properties. The decay rates at these sites are found to be dominated by different mechanisms which are determined by the bottom conditions. As an example, detailed calculations are presented for data ob- tained at the Jonswap site

Dependence of drop speed on nozzle diameter, viscosity and drive amplitude in drop-on-demand ink-jet printing

Results of recent experiments and numerical simulations are presented, which have been used to establish empirical rules for the dependence of drop speed on nozzle diameter and drive amplitude for Newtonian and non-Newtonian fluids printed with a range of different ink-jet print-head technologies. Experiments were carried out with Xaar, MicroFab and Spectra Dimatix print heads and with solutions of polystyrene in diethyl phthalate as model fluids. These results are compared with predictions from recent numerical codes developed by collaborators in the University of Leeds, and from simple models for drop-on-demand fluid jetting resulting from physical law