7,179 research outputs found
Encapsulation of phosphorus dopants in silicon for the fabrication of a quantum computer
The incorporation of phosphorus in silicon is studied by analyzing phosphorus
delta-doped layers using a combination of scanning tunneling microscopy,
secondary ion mass spectrometry and Hall effect measurements. The samples are
prepared by phosphine saturation dosing of a Si(100) surface at room
temperature, a critical annealing step to incorporate phosphorus atoms, and
subsequent epitaxial silicon overgrowth. We observe minimal dopant segregation
(5 nm), complete electrical activation at a silicon growth temperature of 250
degrees C and a high two-dimensional electron mobility of 100 cm2/Vs at a
temperature of 4.2 K. These results, along with preliminary studies aimed at
further minimizing dopant diffusion, bode well for the fabrication of
atomically precise dopant arrays in silicon such as those found in recent
solid-state quantum computer architectures.Comment: 3 pages, 4 figure
Modeling of solvent flow effects in enzyme catalysis under physiological conditions
A stochastic model for the dynamics of enzymatic catalysis in explicit,
effective solvents under physiological conditions is presented.
Analytically-computed first passage time densities of a diffusing particle in a
spherical shell with absorbing boundaries are combined with densities obtained
from explicit simulation to obtain the overall probability density for the
total reaction cycle time of the enzymatic system. The method is used to
investigate the catalytic transfer of a phosphoryl group in a phosphoglycerate
kinase-ADP-bis phosphoglycerate system, one of the steps of glycolysis. The
direct simulation of the enzyme-substrate binding and reaction is carried out
using an elastic network model for the protein, and the solvent motions are
described by multiparticle collision dynamics, which incorporates hydrodynamic
flow effects. Systems where solvent-enzyme coupling occurs through explicit
intermolecular interactions, as well as systems where this coupling is taken
into account by including the protein and substrate in the multiparticle
collision step, are investigated and compared with simulations where
hydrodynamic coupling is absent. It is demonstrated that the flow of solvent
particles around the enzyme facilitates the large-scale hinge motion of the
enzyme with bound substrates, and has a significant impact on the shape of the
probability densities and average time scales of substrate binding for
substrates near the enzyme, the closure of the enzyme after binding, and the
overall time of completion of the cycle.Comment: 15 pages in double column forma
The statistics of particle velocities in dense granular flows
We present measurements of the particle velocity distribution in the flow of
granular material through vertical channels. Our study is confined to dense,
slow flows where the material shears like a fluid only in thin layers adjacent
to the walls, while a large core moves without continuous deformation, like a
solid. We find the velocity distribution to be non-Gaussian, anisotropic, and
to follow a power law at large velocities. Remarkably, the distribution is
identical in the fluid-like and solid-like regions. The velocity variance is
maximum at the core, defying predictions of hydrodynamic theories. We show
evidence of spatially correlated motion, and propose a mechanism for the
generation of fluctuational motion in the absence of shear.Comment: Submitted to Phys. Rev. Let
Correlated magnetic noise in global networks of gravitational-wave detectors: Observations and implications
One of the most ambitious goals of gravitational-wave astronomy is to observe the stochastic gravitational-wave background. Correlated noise in two or more detectors can introduce a systematic error, which limits the sensitivity of stochastic searches. We report on measurements of correlated magnetic noise from Schumann resonances at the widely separated LIGO and Virgo detectors. We investigate the effect of this noise on a global network of gravitational-wave detectors and derive a constraint on the allowable coupling of environmental magnetic fields to test mass motion in gravitational-wave detectors. We find that while correlated noise from global electromagnetic fields could be safely ignored for initial LIGO stochastic searches, it could severely impact Advanced LIGO, Advanced Virgo, KAGRA, as well as third-generation detectors
Three-Dimensional Seismic Imaging of Ancient Submarine Lava Flows : An Example From the Southern Australian Margin
This work comprises a part of the Great Australian Bight Deepwater Marine Program (GABDMP) for funding this project. The GABDMP is a CSIRO research program, sponsored by Chevron Australia the results of which will be made publicly available. 3D seismic data was gratefully provided by TGS. IHS are thanked for access to seismic interpretation software. Spectral decomposition was carried out using Foster-Findlay Associates Geoteric Software. Sverre Planke and Tracy Gregg are thanked for constructive reviews.Peer reviewedPublisher PD
Coleridge, Sara
An encylopaedia article on the life and writings of Sara Coleridge (1802-1852), for an online work of reference and scholarshi
Cluster algebras of type
In this paper we study cluster algebras \myAA of type . We solve
the recurrence relations among the cluster variables (which form a T--system of
type ). We solve the recurrence relations among the coefficients of
\myAA (which form a Y--system of type ). In \myAA there is a
natural notion of positivity. We find linear bases \BB of \myAA such that
positive linear combinations of elements of \BB coincide with the cone of
positive elements. We call these bases \emph{atomic bases} of \myAA. These
are the analogue of the "canonical bases" found by Sherman and Zelevinsky in
type . Every atomic basis consists of cluster monomials together
with extra elements. We provide explicit expressions for the elements of such
bases in every cluster. We prove that the elements of \BB are parameterized
by \ZZ^3 via their --vectors in every cluster. We prove that the
denominator vector map in every acyclic seed of \myAA restricts to a
bijection between \BB and \ZZ^3. In particular this gives an explicit
algorithm to determine the "virtual" canonical decomposition of every element
of the root lattice of type . We find explicit recurrence relations
to express every element of \myAA as linear combinations of elements of
\BB.Comment: Latex, 40 pages; Published online in Algebras and Representation
Theory, springer, 201
Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility
Germline mutations in the von Hippel–Lindau disease (VHL) and succinate dehydrogenase subunit B (SDHB) genes can cause inherited phaeochromocytoma and/or renal cell carcinoma(RCC). Dysregulation of the hypoxia-inducible factor (HIF) transcription factors has been linked to VHL and SDHB-related RCC; both HIF dysregulation and disordered function of a prolyl hydroxylase domain isoform 3 (PHD3/EGLN3)-related pathway of neuronal apoptosis have been linked to the development of phaeochromocytoma. The 2-oxoglutarate-dependent prolyl hydroxylase enzymes PHD1 (EGLN2), PHD2 (EGLN1) and PHD3 (EGLN3) have a key role in regulating the stability of HIF-a subunits (and hence expression of the HIF-a transcription factors). A germline PHD2 mutation has been reported in association with congenital erythrocytosis and recurrent extra-adrenal phaeochromocytoma. We undertook mutation analysis of PHD1, PHD2 and PHD3 in two cohorts of patients with features of inherited phaeochromocytoma (nZ82) and inherited RCC (nZ64) and no evidence of germline mutations in known susceptibility genes. No confirmed pathogenic mutations were detected suggesting that mutations in these genes are not a frequent cause of inherited phaeochromocytoma or RCC
STM characterization of the Si-P heterodimer
We use scanning tunneling microscopy (STM) and Auger electron spectroscopy to
study the behavior of adsorbed phosphine (PH) on Si(001), as a function
of annealing temperature, paying particular attention to the formation of the
Si-P heterodimer. Dosing the Si(001) surface with 0.002 Langmuirs of
PH results in the adsorption of PH (x=2,3) onto the surface and
some etching of Si to form individual Si ad-dimers. Annealing to 350C
results in the incorporation of P into the surface layer to form Si-P
heterodimers and the formation of short 1-dimensional Si dimer chains and
monohydrides. In filled state STM images, isolated Si-P heterodimers appear as
zig-zag features on the surface due to the static dimer buckling induced by the
heterodimer. In the presence of a moderate coverage of monohydrides this static
buckling is lifted, rending the Si-P heterodimers invisible in filled state
images. However, we find that we can image the heterodimer at all H coverages
using empty state imaging. The ability to identify single P atoms incorporated
into Si(001) will be invaluable in the development of nanoscale electronic
devices based on controlled atomic-scale doping of Si.Comment: 6 pages, 4 figures (only 72dpi
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