1,954 research outputs found

    Vertical coordination in high-value commodities

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    "Rising per capita income, urbanization and globalization are changing the consumption basket in the developing countries towards high-value commodities (like fruits & vegetables, milk, meat, poultry, fish, etc.). This paper explores how smallholders can benefit from the emerging opportunities from a silent demand-driven changes in high-value agriculture in India. The study examines the institutional mechanisms adopted by different firms to integrate small producers of milk, broilers and vegetables in supply chain and their effects on producers' transaction costs and farm profitability. The study finds that the innovative institutional arrangements in the form of contract farming have considerably reduced transaction costs and improved market efficiency to benefit the smallholders. The study does not find any bias against smallholders in contract farming. Also, the study does not find that the relevant firms have exploited their monopsonistic position by paying lower prices to farmers. On the contrary, contract producers were found enjoying benefits of assured procurement of their produce and higher prices. The study lists policy hurdles in scaling up the innovative models of vertical coordination in high-value food commodities" Authors' AbstractHigh value commodities ,Urbanization ,High value agriculture ,Scaling up ,

    A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition.

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    GABAA receptors (GABARs) are the targets of a wide variety of modulatory drugs which enhance chloride flux through GABAR ion channels. Certain GABAR modulators appear to acutely enhance the function of δ subunit-containing GABAR subtypes responsible for tonic forms of inhibition. Here we identify a reinforcing circuit mechanism by which these drugs, in addition to directly enhancing GABAR function, also increase GABA release. Electrophysiological recordings in cerebellar slices from rats homozygous for the ethanol-hypersensitive (α6100Q) allele show that modulators and agonists selective for δ-containing GABARs such as THDOC, ethanol and THIP (gaboxadol) increased the frequency of spontaneous inhibitory postsynaptic currents (sIPSCs) in granule cells. Ethanol fails to augment granule cell sIPSC frequency in the presence of glutamate receptor antagonists, indicating that circuit mechanisms involving granule cell output contribute to ethanol-enhancement of synaptic inhibition. Additionally, GABAR antagonists decrease ethanol-induced enhancement of Golgi cell firing. Consistent with a role for glutamatergic inputs, THIP-induced increases in Golgi cell firing are abolished by glutamate receptor antagonists. Moreover, THIP enhances the frequency of spontaneous excitatory postsynaptic currents in Golgi cells. Analyses of knockout mice indicate that δ subunit-containing GABARs are required for enhancing GABA release in the presence of ethanol and THIP. The limited expression of the GABAR δ subunit protein within the cerebellar cortex suggests that an indirect, circuit mechanism is responsible for stimulating Golgi cell GABA release by drugs selective for extrasynaptic isoforms of GABARs. Such circuit effects reinforce direct actions of these positive modulators on tonic GABAergic inhibition and are likely to contribute to the potent effect of these compounds as nervous system depressants

    The logic and linguistic model for automatic extraction of collocation similarity

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    The article discusses the process of automatic identification of collocation similarity. The semantic analysis is one of the most advanced as well as the most difficult NLP task. The main problem of semantic processing is the determination of polysemy and synonymy of linguistic units. In addition, the task becomes complicated in case of word collocations. The paper suggests a logical and linguistic model for automatic determining semantic similarity between colocations in Ukraine and English languages. The proposed model formalizes semantic equivalence of collocations by means of semantic and grammatical characteristics of collocates. The basic idea of this approach is that morphological, syntactic and semantic characteristics of lexical units are to be taken into account for the identification of collocation similarity. Basic mathematical means of our model are logical-algebraic equations of the finite predicates algebra. Verb-noun and noun-adjective collocations in Ukrainian and English languages consist of words belonged to main parts of speech. These collocations are examined in the model. The model allows extracting semantically equivalent collocations from semi-structured and non-structured texts. Implementations of the model will allow to automatically recognize semantically equivalent collocations. Usage of the model allows increasing the effectiveness of natural language processing tasks such as information extraction, ontology generation, sentiment analysis and some others

    Agriculture diversification in South Asia

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    The South Asian countries are gradually diversifying with some inter-country variation in favor of high value commodities, namely fruits, vegetables, livestock and fisheries. Agricultural diversification is strongly influenced by price policy, infrastructure development (especially markets and roads), urbanization and technological improvements. Rainfed areas have benefited more as a result of agricultural diversification in favor of high value crops by substituting inferior coarse cereals. Agricultural diversification is also contributing to employment opportunities in agriculture and increasing exports. The need is to suitably integrate production and marketing of high value commodities through appropriate institutions. Market reforms in developing and strengthening desired institutions through required legal changes would go a long way in boosting agricultural growth, augmenting income of small farm holders and promoting exports.Agricultural diversification Economic aspects ,price policies ,Urbanization ,Technological innovations ,South Asia Economic conditions ,Markets Economic policy ,Agricultural growth ,

    Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2.

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    Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited disorder, which is caused by a pathological expansion of a polyglutamine (polyQ) tract in the coding region of the ATXN2 gene. Like other ataxias, SCA2 most overtly affects Purkinje cells (PCs) in the cerebellum. Using a transgenic mouse model expressing a full-length ATXN2(Q127)-complementary DNA under control of the Pcp2 promoter (a PC-specific promoter), we examined the time course of behavioral, morphologic, biochemical and physiological changes with particular attention to PC firing in the cerebellar slice. Although motor performance began to deteriorate at 8 weeks of age, reductions in PC number were not seen until after 12 weeks. Decreases in the PC firing frequency first showed at 6 weeks and paralleled deterioration of motor performance with progression of disease. Transcription changes in several PC-specific genes such as Calb1 and Pcp2 mirrored the time course of changes in PC physiology with calbindin-28 K changes showing the first small, but significant decreases at 4 weeks. These results emphasize that in this model of SCA2, physiological and behavioral phenotypes precede morphological changes by several weeks and provide a rationale for future studies examining the effects of restoration of firing frequency on motor function and prevention of future loss of PCs
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