56 research outputs found

    Improvement in vanadium-containing titanomagnetite processing technology

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    The article describes the modern technology of iron smelting from vanadium-containing titanomagnetite. The complex of research presented by the NTMK team and the leading research teams of the Ural Institute of metals, the metallurgical Institute of the Ural branch of the Russian Academy of Sciences, and the Ural Federal University is the basis for achieving high productivity of the blast furnaces EVRAZ NTMK. The presented research and development works are the basis for the technology of metallurgical processing of vanadium-containing titanomagnetite. The developed technology makes it possible to achieve high rates of melting intensity and total consumption of carbon contained in the fuel. Such indicators are achieved by reconstruction, namely by changing the line of the working space of the blast furnace. Modern loading devices were used, energy-efficient technology of coal-dust fuel intake was introduced, and the oxygen content in the air was increased. Considerable attention is paid to the analysis of the domain process and problems of domain melting of titanomagnetite. Particular attention is paid to the implementation of measures to reduce the content of titanium in cast iron. Β© Published under licence by IOP Publishing Ltd

    Π›Π΅Π³ΠΎΡ‡Π½Ρ‹ΠΉ гистиоцитоз ΠΈΠ· ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ЛангСрганса, ΡΠΈΠΌΡƒΠ»ΠΈΡ€ΡƒΡŽΡ‰ΠΈΠΉ мСтастазы Π² Π»Π΅Π³ΠΊΠΈΠ΅ Π³ΠΈΠ³Π°Π½Ρ‚ΠΎΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΠΎΠΉ остСобластичСской саркомы (клиничСскоС наблюдСниС)

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    Langerhans cell histiocytosis is a clonal neoplastic process characterized by cell proliferation of the Langerhans type, with the expression of CD1a, CD207 and S100 proteins and the presence of Birbek granules. We present a case of a 31-year-old woman with a verified osteosarcoma of the proximal epimetaphysis of the left tibia. Also she has multiple thin-walled cysts and foci in the lungs. The case is interesting for the rare combination of osteosarcoma of the bone and pulmonary histiocytosis. This case show that foci in lungs can simulates metastatic disease according to computed tomography (CT). Multidisciplinary approach of pathologist, oncologist and radiologist help revealed diagnose.Гистиоцитоз ΠΈΠ· ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ЛангСрганса – ΠΊΠ»ΠΎΠ½Π°Π»ΡŒΠ½Ρ‹ΠΉ нСопластичСский процСсс, Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΡŽΡ‰ΠΈΠΉΡΡ ΠΏΡ€ΠΎΠ»ΠΈΡ„Π΅Ρ€Π°Ρ†ΠΈΠ΅ΠΉ ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ΠΏΠΎ Ρ‚ΠΈΠΏΡƒ ЛангСрганса, с экспрСссиСй Π±Π΅Π»ΠΊΠΎΠ² CD1a, CD207 ΠΈ S100 ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ΠΌ Π³Ρ€Π°Π½ΡƒΠ» Π‘ΠΈΡ€Π±Π΅ΠΊΠ°.Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСно клиничСскоС наблюдСниС 31-Π»Π΅Ρ‚Π½Π΅ΠΉ ΠΆΠ΅Π½Ρ‰ΠΈΠ½Ρ‹ с Π²Π΅Ρ€ΠΈΡ„ΠΈΡ†ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠΉ остСосаркомой ΠΏΡ€ΠΎΠΊΡΠΈΠΌΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ эпимСтафиза Π»Π΅Π²ΠΎΠΉ Π±ΠΎΠ»ΡŒΡˆΠ΅Π±Π΅Ρ€Ρ†ΠΎΠ²ΠΎΠΉ кости, Π½Π° Ρ„ΠΎΠ½Π΅ ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠΉ Π±Ρ‹Π»ΠΈ выявлСны мноТСствСнныС тонкостСнныС кисты ΠΈ ΠΎΡ‡Π°Π³ΠΈ Π² Π»Π΅Π³ΠΊΠΈΡ…. НаблюдСниС интСрСсно Ρ€Π΅Π΄ΠΊΠΎΡΡ‚ΡŒΡŽ сочСтания остСосаркомы кости ΠΈ Π»Π΅Π³ΠΎΡ‡Π½ΠΎΠ³ΠΎ гистиоцитоза, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΡΠ»ΠΎΠΆΠ½ΠΎΡΡ‚ΡŒΡŽ, Π½ΠΎ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡ‚ΡŒΡŽ Π΄ΠΈΡ„Ρ„Π΅Ρ€Π΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ диагностики мСтастатичСского пораТСния Π»Π΅Π³ΠΊΠΈΡ… ΠΈ пораТСния Π»Π΅Π³ΠΊΠΈΡ… ΠΏΡ€ΠΈ гистиоцитозС ΠΈΠ· ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ЛангСрганса ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ ΠΊΠΎΠΌΠΏΡŒΡŽΡ‚Π΅Ρ€Π½ΠΎΠΉ Ρ‚ΠΎΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ ΠΈ патоморфологичСского исслСдования

    ΠœΠΎΠ»Π΅ΠΊΡƒΠ»ΡΡ€Π½Ρ‹Π΅ ΠΏΠΎΠ΄Ρ‚ΠΈΠΏΡ‹ Ρ€Π°ΠΊΠ° ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря ΠΈ ΠΏΠ΅Ρ€Π²Ρ‹Π΅ успСхи Π² пСрсонализированном Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ.

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    In the literature review we described studies, the main purpose of which was to distribute bladder tumors by molecular subtypes. A similar classification has long been actively used in the treatment of breast cancer. The pioneering work in the molecular subtypes of bladder cancer includes the work by Lund group, the TCGA (The Cancer Genome Atlas) project, the MD Anderson study. We have also included data on attempts to apply molecular taxonomy of bladder cancer in treatment.Π’ прСдставлСнном ΠΎΠ±Π·ΠΎΡ€Π΅ Π»ΠΈΡ‚Π΅Ρ€Π°Ρ‚ΡƒΡ€Ρ‹ рассмотрСны исслСдования, основной Ρ†Π΅Π»ΡŒΡŽ ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… Π±Ρ‹Π»ΠΎ Ρ€Π°ΡΠΏΡ€Π΅Π΄Π΅Π»ΠΈΡ‚ΡŒ ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря ΠΏΠΎ молСкулярным ΠΏΠΎΠ΄Ρ‚ΠΈΠΏΠ°ΠΌ. БхоТая классификация ΡƒΠΆΠ΅ Π΄Π°Π²Π½ΠΎ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΠ΅Ρ‚ΡΡ ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹. К ΠΎΡΠ½ΠΎΠ²ΠΎΠΏΠΎΠ»Π°Π³Π°ΡŽΡ‰ΠΈΠΌ Ρ€Π°Π±ΠΎΡ‚Π°ΠΌ Π² области молСкулярных ΠΏΠΎΠ΄Ρ‚ΠΈΠΏΠΎΠ² Ρ€Π°ΠΊΠ° ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря относятся исслСдования Π³Ρ€ΡƒΠΏΠΏΡ‹Β Π›ΡƒΠ½Π΄Π°, ΠΏΡ€ΠΎΠ΅ΠΊΡ‚ TCGA, исллСдования MDΒ Anderson. Π’Π°ΠΊΠΆΠ΅, ΠΌΡ‹ Π²ΠΊΠ»ΡŽΡ‡ΠΈΠ»ΠΈ Π΄Π°Π½Π½Ρ‹Π΅ ΠΎ ΠΏΠΎΠΏΡ‹Ρ‚ΠΊΠ°Ρ… примСнСния молСкулярной таксономии Ρ€Π°ΠΊΠ° ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря Π² Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ.Β 

    ΠŸΠ Π˜ΠœΠ•ΠΠ•ΠΠ˜Π• 3D-ΠœΠžΠ”Π•Π›Π•Π™ БЕРДЦА, Π‘ΠžΠ—Π”ΠΠΠΠ«Π₯ НА ΠžΠ‘ΠΠžΠ’Π• DICOM-Π˜Π—ΠžΠ‘Π ΠΠ–Π•ΠΠ˜Π™, Π’ ΠœΠ•Π”Π˜Π¦Π˜ΠΠ‘ΠšΠžΠ™ ΠŸΠ ΠΠšΠ’Π˜ΠšΠ•

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    Three-dimensional printing (3D printing, additive manufacturing, rapid prototyping) is a technology of a physical object creation fromΒ digital model by layered addition of material. Additive technologies differ from mass production by personalization, customization and relative simplicity of 3D-models creation. 3D models ability toΒ  demonstrate heart anatomy is of use in cardiac surgery, primarily during theΒ educational process and preoperative planning and, less common, for implantable devices testing and hemodynamic modeling. AlthoughΒ the role of 3D models in clinical practice is not currently defined, 3D printing mass application can provide important advantages to solveΒ a number of diagnostic and therapeutic issues. The article presents the revue of scientific publications describing the use of physicalΒ three-dimensional heart models in cardiac surgery.ВрСхмСрная ΠΏΠ΅Ρ‡Π°Ρ‚ΡŒ (3D-ΠΏΠ΅Ρ‡Π°Ρ‚ΡŒ, Π°Π΄Π΄ΠΈΡ‚ΠΈΠ²Π½ΠΎΠ΅ производство, быстроС ΠΏΡ€ΠΎΡ‚ΠΎΡ‚ΠΈΠΏΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅) – это тСхнология создания физичСского ΠΎΠ±ΡŠΠ΅ΠΊΡ‚Π° ΠΈΠ· Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠΉ ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΡƒΡ‚Π΅ΠΌ послойного добавлСния ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Π°. ΠžΡ‚Π½ΠΎΡΠΈΡ‚Π΅Π»ΡŒΠ½Π°Ρ простота создания 3D-ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ, ΠΈΡ… индивидуализация ΠΈ кастомизация ΠΎΡ‚Π»ΠΈΡ‡Π°ΡŽΡ‚ Π°Π΄Π΄ΠΈΡ‚ΠΈΠ²Π½Ρ‹Π΅ Ρ‚Π΅Ρ…Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΎΡ‚ сСрийного производства. Π’ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡ‚ΡŒΒ Π΄Π΅ΠΌΠΎΠ½ΡΡ‚Ρ€ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ Π°Π½Π°Ρ‚ΠΎΠΌΠΈΡŽ сСрдца с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ 3D-ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΠΈΠ»Π° ΠΈΡ…Β  использованиС Π² ΠΊΠ°Ρ€Π΄ΠΈΠΎΡ…ΠΈΡ€ΡƒΡ€Π³ΠΈΠΈ, Π² ΠΏΠ΅Ρ€Π²ΡƒΡŽ ΠΎΡ‡Π΅Ρ€Π΅Π΄ΡŒ, Π² Ρ…ΠΎΠ΄Π΅ ΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠ³ΠΎ процСсса ΠΈΒ  ΠΏΡ€Π΅Π΄ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ планирования, Π° Ρ‚Π°ΠΊΠΆΠ΅ для тСстирования имплантируСмых устройств ΠΈ модСлирования Π³Π΅ΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ. НСсмотря Π½Π° Ρ‚ΠΎ, Ρ‡Ρ‚ΠΎ Ρ€ΠΎΠ»ΡŒ 3D-ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ Π² клиничСской  ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅ Π² настоящСС врСмя Π½Π΅ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Π°, Π²Π½Π΅Π΄Ρ€Π΅Π½ΠΈΠ΅ 3D-ΠΏΠ΅Ρ‡Π°Ρ‚ΠΈ способно Π΄Π°Ρ‚ΡŒ Π²Π°ΠΆΠ½Ρ‹Π΅Β  прСимущСства Π² Ρ€Π΅ΡˆΠ΅Π½ΠΈΠΈ ряда диагностичСских ΠΈ Π»Π΅Ρ‡Π΅Π±Π½Ρ‹Ρ… Π·Π°Π΄Π°Ρ‡. Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ прСдставлСны  Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ Π°Π½Π°Π»ΠΈΠ·Π° Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… статСй, посвящСнных ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡŽ Ρ‚Ρ€Π΅Ρ…ΠΌΠ΅Ρ€Π½Ρ‹Ρ… физичСских модСлСй сСрдца Π² кардиохирургичСской ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅

    Molecular subtypes of bladder cancer and first success in personalized treatment

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    In the literature review we described studies, the main purpose of which was to distribute bladder tumors by molecular subtypes. A similar classification has long been actively used in the treatment of breast cancer. The pioneering work in the molecular subtypes of bladder cancer includes the work by Lund group, the TCGA (The Cancer Genome Atlas) project, the MD Anderson study. We have also included data on attempts to apply molecular taxonomy of bladder cancer in treatment

    Optimization of the width of the transportation corridor of tractor trains for agricultural purpose

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    The main works related to the production and transportation of crop production take place in the Amur region in conditions when the surface of the movement has a weak carrying capacity, which imposes additional requirements on transport units to increase their traction-chain properties.So the issue of exporting crop products from the fields is important and relevant both for peasant farms (PF) and for private farms. The use of multi-link tractor trains (MTU) in the region is limited by a significant deterrent, such as the increase in the width of the transport corridor in turns. Why the issue of increasing the efficiency of the ICC should be considered both in the direction of increasing traction-chain properties, and at the same time optimizing the width of the transport corridor when it moves. The proposed article provides theoretical, experimental research and experience with the use of the designer and scientific novelty, designed to enhance traction-clutch properties and reduce the width of the MTU corridor in an arbitrary turn

    The geometry and curvature of shape spaces

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