21 research outputs found
Hereditary Hemorrhagic Telangiectasia or Rendu-Osler-Weber Syndrome in the Same Family
The authors present the case of three patients from the same family in whom hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler-Weber syndrome was diagnosed. The disease is rare and occurs with multiple telangiectases of the skin and mucosa, and pulmonary arteriovenous fistulae. The clinical status of our patients included multiple telangiectases of the skin and mucosa, recurrent epistaxis, exertion dyspnea and cyanosis. Polycythemia and hypoxemia were observed in the blood. The clinical status and conventional radiological examination of the thoracic region, with the suspicion of arteriovenous (A-V) fistulae, pointed to HHT. A-V fistulae were confirmed by pulmonary angiography. The pulmonary A-V fistulae were operated in all three patients and diagnosis was confirmed by histopathological examination of the operated samples. Clinical improvement was observed after the operation and cyanosis, dyspnea, hypoxemia and polycythemia disappeared
Psychosocial Characteristics of Patients with Bronchial Asthma and Coronary Disease: Similarities and Differences
The authors compare two groups of subjects: patients with bronchial asthma and
those with coronary disease, with regard to some social characteristics, abilities and
perception of factors which they conceive are important in the etiology of their disease.
Data were obtained by means of a questionnaire based on a known calibrated scale. A
group of 100 patients with bronchial asthma and a group of 102 patients with coronary
disease were examined. The significance of the difference was tested by c
2, t-test, Wilcoxonās
test and multivariate discriminative analysis.
The results showed statistically significant differences between the patients with
bronchial asthma and those with coronary disease in some social and psychological
characteristics and also with regard to perception of potential etiological factors of their
disease. However, no difference was found in life style and habits between the coronary
and asthmatic patients
Aberrant Mucin5B expression in lung adenocarcinomas detected by iTRAQ labeling quantitative proteomics and immunohistochemistry
Sequence-controlled methacrylic multiblock copolymers via sulfur-free RAFT emulsion polymerization
Perception of Ecological Factors in Asthmatic and Coronary Patients
The aim of the study was to determine whether an examined group of asthmatic patients
differ significantly from a control group of coronary patients with regard to perception
of two groups of etiological factors and their interaction: a) ecological factors,
and b) habits and behavior of the patients. The study included 100 patients with bronchial
asthma and 102 with coronary disease. A questionnaire was used to obtain data
on ecological factors in the living environment of the patients and information on habits
and behavior. The questionnaire was structured according to the specific needs of the
study, and as a starting point known, calibrated, psychometric scales were used. Asthmatic
and coronary patients did not differ with regard to their place of residence, i.e. the
same number lived in the town and village, in similar ecological environments, and
they also did not differ with regard to life style and habits. The study indicated statistically
significant differences between asthmatic and coronary patients in their perception
of several ecological and other risk factors. The asthmatic patients significantly
more frequently perceived harmful ecological factors in their environment and regarded
them significant for the occurrence of their disease. The coronary patients perceived
their unhealthy habits and behavior as the causal factors of their disease
Novel polymers from atom transfer polymerisation mediated by copper(I) Schiff base complexes
The use of copper(I) Schiff base complex catalysed atom transfer polymerisation of methacrylates is described. The use of a range of functional and multi-functional initiators enables the synthesis of a range of functional and star polymers to be prepa
Sequence-controlled methacrylic multiblock copolymers via sulfur-free RAFT emulsion polymerization
Translating the precise monomer sequence control achieved in nature over macromolecular structure (for example, DNA) to whole synthetic systems has been limited due to the lack of efficient synthetic methodologies. So far, chemists have only been able to synthesize monomer sequence-controlled macromolecules by means of complex, time-consuming and iterative chemical strategies such as solid-state Merrifield-type approaches or molecularly dissolved solution-phase systems. Here, we report a rapid and quantitative synthesis of sequence-controlled multiblock polymers in discrete stable nanoscale compartments via an emulsion polymerization approach in which a vinyl-terminated macromolecule is used as an efficient chain-transfer agent. This approach is environmentally friendly, fully translatable to industry and thus represents a significant advance in the development of complex macromolecule synthesis, where a high level of molecular precision or monomer sequence control confers potential for molecular targeting, recognition and biocatalysis, as well as molecular information storage