Evaluation of the hierarchical temporal memory soft computing platform and its VLSI architecture

A large number of real world applications, like user support systems, can still not be performed easily by conventional algorithms in comparison with the human brain. Recently, such intelligence has often been reached by using probability based systems. This paper presents results on the implementation of one such user support system, namely an intention estimation information appliance system, on a Bayesian network as well as hierarchical temporal memory. The latter is a new and quite promising soft computing platform modelling the human brain, though currently only available as a software model. A second part of the paper therefore focuses on a possible VLSI architecture for hierarchical temporal memory. Since it models the human brain, communication as well as memory are of high importance for this VLSI architecture

Beitrag zur Kenntnis uber die Blut-Liquorschranke. I) Veränderungen der Blut-Liquorschranke bei experimentell erzeugtem Fieber

Es ist schon von mehreren Autoren am Krankenbett angenommen worden, dass das Fieber irgendeinen bestimmten Einfluss auf die Blut-Liquorschranke ausübt, experimehtelle Studien in dieser Frage lagen aber bisjetzt noch nicht vor. Daher untersuchte ich an Kaninchen mittels der Walterschen Brommethode die Permeabilität der Meningen nach Verabreichung verschiedener fiebererzeugender Mittel, wie Typhusvaccin und Tetrahydro-β-Naphthylamin (Thermin), und auch nach dem Wärmestich; die Versuche wurden in folgender Weise ausgeführt: Jedem Kaninchen wurden täglich je 2ccm einer 10%igen Bromnatriumlosung 10 Tage lang fortgesetzt intravenös injiziert; am 6, sowie 10. Bromtage wurden das Ohrvenenblut und das Liquor auf ihren Bromgehalt untersucht und die sog. Permeabilitätsquotienten von normalen und fiebernden Kaninchen verglichen, indem dabei Typhusvaccin (intravenös, je 2ccm) bzw. Thermin (subcutan, je 1ccm der 5%igen Losung) bald nur einmal am 5. Bromtage, bald 3mal an jedem zweiten Tage, vom 1. Tage an gerechnet, injiziert wurde. 1) Sowohl nach einmaliger als auch nach dreimaliger Vaccin-bzw. Thermininjektion zeigte sich eine gesteigerte Permeabilität der Meningen am sechsten Bromtage; diese kehrte bei den nur einmal vorbehandelten Tieren schon am 10. Bormtage fast zum normalen Stand zuruck, nich jedoch bei den Tieren, die 3 Injektionen erhalten hatten. Im allgemeinen schien die Permeabilitätssteigerung beim Therminfieber stärker zn sein als beim Vaccinfieber. 2) Beim Wärmestichfieber war die Permeabilität nicht nur am sechsten, sondern auch am zehnten Bromtage erhoht. Nach diesen Ergebnissen darf man wohl behaupten, dass die experimentelle Fiebererzeugung auf die Permeabilität der Meningen im steigernden Sinne wirkt

Design of a Multi-Context FPGA Using a Floating-Gate-MOS Functional Pass-Gate

科研費報告書収録論文(課題番号:17300009/研究代表者:亀山充隆/システムインテグレーション理論に基づく高安全知能自動車用VLSIの最適設計

Technical Note: Determination of formaldehyde mixing ratios in polluted air with PTR-MS: laboratory experiments and field measurements

International audienceFormaldehyde (HCHO), the most abundant carbonyl compound in the atmosphere, is generated as an intermediate product in the oxidation of nonmethane hydrocarbons. Proton transfer reaction mass spectrometry (PTR-MS) has the capability to detect HCHO from ion signals at m/z 31 with high time-resolution. However, the detection sensitivity is low compared to other detectable species, and is considerably affected by humidity, due to back reactions between protonated HCHO and water vapor prior to analysis. We performed a laboratory calibration of HCHO by PTR-MS and examined the detection sensitivity and humidity dependence at various field strengths. Subsequently, we deployed the PTR-MS instrument in a field campaign at Mount Tai in China in June 2006 to measure HCHO in various meteorological and photochemical conditions; we also conducted intercomparison measurements by Multi-Axis Differential Optical Absorption Spectroscopy (MAX-DOAS). Correction of interference in the m/z 31 signals by fragments from proton transfer reactions with methyl hydroperoxide, methanol, and ethanol greatly improves agreement between the two methods, giving the correlation [HCHO]MAX-DOAS = (0.99±0.16) [HCHO]PTR-MS + (0.02±0.38), where error limits represent 95% confidence levels

Expression of SART3 antigen and induction of CTLs by SART3-derived peptides in breast cancer patients

We recently reported the SART3 tumour-rejection antigen as possessing tumour epitopes capable of inducing HLA-class I-restricted cytotoxic T lymphocytes (CTLs). This study investigated expression of the SART3 antigen in breast cancer to explore an appropriate molecule for use in specific immunotherapy of breast cancer patients. The SART3 antigen was detected in all of the breast cancer cell lines tested, 30 of 40 (75%) breast cancer tissue samples, and 0 of 3 non-tumourous breast tissue samples. SART3 derived peptides at positions 109–118 and 315–323 induced HLA-A24 restricted CTLs that reacted to breast cancer cells from the peripheral blood mononuclear cells (PBMCs) of breast cancer patients. Therefore, the SART3 antigen and its peptides could be an appropriate molecule for use in specific immunotherapy of the majority of HLA-A24-positive breast cancer patients. © 2001 Cancer Research Campaignhttp://www.bjcancer.co

Quantitative Evaluation of L-[methyl-C-11]Methionine Uptake in Tumor Using Positron Emission Tomography

開始ページ、終了ページ: 冊子体のページ付

Generator Coordinate Method Calculations for Ground and First Excited Collective States in 4^{4}He, 16^{16}O and 40^{40}Ca Nuclei

The main characteristics of the ground and, in particular, the first excited monopole state in the $^{4}$He, $^{16}$O and $^{40}$Ca nuclei are studied within the generator coordinate method using Skyrme-type effective forces and three construction potentials, namely the harmonic-oscillator, the square-well and Woods-Saxon potentials. Calculations of density distributions, radii, nucleon momentum distributions, natural orbitals, occupation numbers and depletions of the Fermi sea, as well as of pair density and momentum distributions are carried out. A comparison of these quantities for both ground and first excited monopole states with the available empirical data and with the results of other theoretical methods are given and discussed in detail.Comment: 15 pages, LaTeX, 6 Postscript figures, submitted to EPJ

The Dissociation Between Glucose and Amino Acid Metabolism in Brain Tumor - Clinical and Experimental Study -

開始ページ、終了ページ: 冊子体のページ付

The Accumulation of 11C-Methionine and Histological Grade in Cerebral Glioma Studied with PET

開始ページ、終了ページ: 冊子体のページ付

Biological Malignancy and 18FdUrd Uptake in Glioma Patients - PET Study of Nucleic Acid Metabolism

開始ページ、終了ページ: 冊子体のページ付