A STUDY ON THE EFFECT OF LOW MOLECULAR WEIGHT ON POTASSIUM HOMEOSTASIS IN PATIENTS ADMINISTERED HEPARIN FOR THROMBOPROPHYLAXIS IN A TERTIARY CARE HOSPITAL

Objective: Low molecular weight heparin (LMWH) is an indirect thrombin inhibitor used clinically as an anticoagulant for thromboprophylaxis of patients at risk of deep vein thrombosis. The study was done to assess the magnitude of rise in serum potassium after administration of low molecular weight heparin comparing enoxaparin with dalteparin and to evaluate the frequency of clinically significant hyperkalemia in the population studied.Methods: The study was done as a prospective non-randomized observational study in a population of 32 patients started on heparin for thromboprophylaxis for deep venous thrombosis, pulmonary thromboembolism or stroke.Results: A statistically significant elevation in serum potassium was seen in patients treated with LMWH (p = 0.007). The magnitude of rise in potassium was significantly higher in enoxaparin (p = 0.008) than the dalteparin group (p = 0.447). A clinically relevant hyperkalemia of>5 mEq/l was seen in 25% of the population studied. Other important associations detected from the study were that the advancing age and increasing dose could be potential risk factors contributory to an accentuated rise in serum potassium which may culminate in clinically significant hyperkalemia.Conclusion: The study has highlighted that the likelihood of rise in potassium levels during LMWH therapy necessitates monitoring of serum potassium

VASANTIKAVAMANA A PREVENTIVE MEASURE FOR KAPHAJA ROGAS

The aims and objective of Ayurveda is of two fold i.e., Prevention of disease in healthy individual and cure of the disease in a diseased person. To fulfil the first aim, our Acharyas have described Dinacharya, Rutucharya. In Dosha chaya, Prakopaavastha, if the person consumes more Apathyakaraahara, Vihara, Doshas will go in Prasaraadiavast has and leads to Vyadhi. Ayurveda emphasized to practise these therapies to eliminate the vitiated Dosha in accordance to the seasonal variation like Vamana in Vasantharutu, Virechana in Sharadrutu, Basti in Pravrutrutu, as a prevention of disease and promotion of health. Person who follows this regimen in each season never suffers from severe disorderAccording to Induteeka, thus neglected, the vitiated Dosha get accumulated over the time to its maximum, and the channels of rasa are being obstructed by the vitiated Dosha (deposition of debries in the inner layers making the lumen narrowed), nourishment to the tissues is not possible. This causes the diseases like Sthoulya, Agnisada, Kusta, Meha etc, which are not amenable for treatment. 4 Maasa (Rutudvaya) for Sanchaya of Kaphadosha, if it is not early evacuated in Chaitramaasa it end up in Rutujaan rogas. Hence, while maintaining health itself one must undergo purifactory measures to prevent from occurrence of the diseases by seasonal factors. Hence this conceptual study is made to explain the effect of Vasantikavamana a preventive measure for Kaphaja rogas.

ROLE OF PADA ABHYANGA AS PREVENTIVE ASPECT W.S.R TO EYE DISORDERS: A CONCEPTUAL STUDY

Ayurveda aimed in prevention and cure of physical and mental health. In Ayurveda, Dinacharya is one of the concept which helps to fulfill this aim of Ayurveda. Vitality enhancing technique which is incorporated in massage of the feet is called Padabhyanga. It is one of the prophylactic principles mentioned in Ayurvedic dinacharya. The hectic computerised life style, faulty food habits, stress and strain, irregular sleeping habits and negligence in following daily and seasonal regimen provoke many eye problems. By doing Padaabhyanga, Kharatwa, Stabdata, Rukshata, Shrama, Suptata of pada relieved and Bala, Sthairya improved, Drustiprasaadakara. It also prevents Grudrasi vaata, Pada sputana, Sirasnaayu sankocha.In the centre of the feet 2 Siras are situated which are directly connected to the eyes, these transmit the effect of the medicines applied over the feet in the form of massage. Hence every person should need make use of Padabhyanga. Major cause of blindness for prevalence are cataract, glaucoma, diabetic retinopathy, Age related macular degeneration, refractive errors. There by Paada Abhyanga through its Vaata-ameliorating action is responsible for better function of Chakshurindriya. According to Sushrutacharya, by practice of Snehana karma, which results in Utpatti of Pratyagradhatu – Navadhatu. such that degenerative changes related to eye are antagonized by the Snehana karma. Padaabhyanga is helpful in preventing above said diseases which causes the blindness. Hence this conceptual study is made to explain the mode of action and effect of Pada Abhyanga to increase and maintain the visual acuity

Urological injuries during obstetric and gynaecological procedures: a retrospective analysis over a period of eleven years

Background: To determine frequency and nature of urological injuries in obstetric and gynaecological procedures and their consequences and mode of management in a tertiary care hospital SDM Medical college and hospital, Dharwad, India.Methods: A retrospective study of all obstetric and gynaecological surgeries over a period of 11 years from January 2004 to December 2014 was carried out at Department of Obstetrics and Gynaecology, SDM Medical College and Hospital, Dharwad, India. Cases with the documented urological injuries were analyzed further. A total of 18,250 patients underwent obstetric and gynaecological procedures like lower segment caesarean section, various types of hysterectomies were analyzed. Cases with urologic injuries were identified and analyzed for risk factor, timing of diagnosis, their management and consequences.Results: Out of 18,250 patients undergoing various surgeries, 37(0.2%) patients had bladder injury and 4(0.02%) patients had ureteric injury. In gynecologic procedures, the incidence of bladder injury was highest in radical hysterectomy (2 out of 79, 2.5%) followed by TLH/LAVH (4 out of 299, 1.3%), NDVH (7 out of 490, 1.4%) TAH (5 out of 1360, 0.37%), laparotomy (1 out of 347, 0.29%) and vaginal hysterectomy (3 out of 1529, 0.2%). Three ureteric injuries were noted in cases of TLH/LAVH (3 out of 299) and one in case of TAH (1 out of 1360, 0.07%).Conclusions: Even though urological injuries are statistically rare, they are responsible for significant morbidity. Bladder injuries are more common, but are easy to manage with earlier diagnosis. Ureteric injuries which are usually diagnosed late and hence cause more morbidity than bladder injuries

FACTORS INFLUENCING JOB REJECTIONS IN CLOUD ENVIRONMENT

The IT organizations invests heavy capital by consuming large scale infrastructure and advanced operating platforms. The advances in technology has resulted in emergence of cloud computing, which is promising technology to achieve the aforementioned objective. At the peak hours, the jobs arriving to the cloud system are normally high demanding efficient execution and dispatch. An observation that has been carried out in this paper by capturing a job arriving pattern from a monitoring system explains that most of the jobs get rejected because of lack of efficient technology. The job rejections can be controlled by certain factors such as job scheduling and load balancing. Therefore, in this paper the efficiency of Round Robin (RR) scheduling strategy used for job scheduling and Shortest Job First Scheduling (SJFS) technique used for load balancing in reducing the job rejections are analyzed. Further, a proposal for an effective load balancing approach to avoid deadlocks has been discussed

Flexible Deep Learning in Edge Computing for Internet of Things

Deep learning is a promising approach for extracting accurate information from raw sensor data from IoT devices deployed in complex environments. Because of its multilayer structure, deep learning is also appropriate for the edge computing environment. Traditional edge computing models have rigid characteristics. Flexible edge computing architecture solves rigidity in IoT edge computing. Proposed model combines deep learning into edge computing and flexible edge computing architecture using multiple agents. Since existing edge nodes have limited processing capability, we also design a novel offloading strategy to optimize the performance of IoT deep learning applications with edge computing. FEC architecture is a flexible and advanced IoT system model characterized by environment adaptation ability and user orientation ability. In the performance evaluation, we test the performance of executing deep learning tasks in FEC architecture for edge computing environment. The evaluation results show that our method outperforms other optimization solutions on deep learning for IoT

Flexible Deep Learning in Edge Computing for Internet of Things

Deep learning is a promising approach for extracting accurate information from raw sensor data from IoT devices deployed in complex environments. Because of its multilayer structure, deep learning is also appropriate for the edge computing environment. Traditional edge computing models have rigid characteristics. Flexible edge computing architecture solves rigidity in IoT edge computing. Proposed model combines deep learning into edge computing and flexible edge computing architecture using multiple agents. Since existing edge nodes have limited processing capability, we also design a novel offloading strategy to optimize the performance of IoT deep learning applications with edge computing. FEC architecture is a flexible and advanced IoT system model characterized by environment adaptation ability and user orientation ability. In the performance evaluation, we test the performance of executing deep learning tasks in FEC architecture for edge computing environment. The evaluation results show that our method outperforms other optimization solutions on deep learning for IoT

Study of demographic features in retropositive pregnant women

Background: Study of demographic features like age, educational status of the patient and her husband, occupation of the patient and her husband and religion of the retropositive pregnant women compared to controls.Methods: In this prospective study patients were selected from Vani Vilas Hospital attached to Bangalore Medical College attending the antenatal Clinic of Obstetrics and Gynaecology. The study period was for 2 years. The study group comprised of 100 HIV seropositive patients. The control group comprised of 100 HIV seronegative patients. At enrollment, data collection of demographic features like age, educational status of the patient and her husband, occupation of patient and her husband, and religion of the retropositive pregnant women compared to controls.Results: The minimum and maximum age in the study group was 18 and 36 years respectively and in the control group 17 and 35 years respectively. Around 73% of pregnant women in the study group were below 25 years of age. 89% of pregnant women in the study group were Hindus. Around 36% of women in the study group were illiterate compared to 21% in the control group. Around 45% of women in the control group have studied till secondary school. In this study, most of the women in both the groups were housewives. There was one commercial sex worker and 8 women had polygamous relationship in the study group. The occupational pattern of the husbands was analyzed and 34% of the husbands of HIV positive women were drivers. 56% of the husbands in the study group admitted to have had multiple sexual partners, whereas only 9% admitted so, in the control group.Conclusions: Retropositive pregnant women were younger; most of them were house wives. Husbands of retropositive pregnant women were drivers and most of them had multiple sexual partners