15,488 research outputs found
A functional analysis of two transdiagnostic, emotion-focused interventions on nonsuicidal self-injury
OBJECTIVE: Nonsuicidal self-injury (NSSI) is prevalent and associated with clinically significant consequences. Developing time-efficient and cost-effective interventions for NSSI has proven difficult given that the critical components for NSSI treatment remain largely unknown. The aim of this study was to examine the specific effects of mindful emotion awareness training and cognitive reappraisal, 2 transdiagnostic treatment strategies that purportedly address the functional processes thought to maintain self-injurious behavior, on NSSI urges and acts.
METHOD: Using a counterbalanced, combined series (multiple baseline and data-driven phase change) aggregated single-case experimental design, the unique and combined impact of these 2 4-week interventions was evaluated among 10 diagnostically heterogeneous self-injuring adults. Ecological momentary assessment was used to provide daily ratings of NSSI urges and acts during all study phases.
RESULTS: Eight of 10 participants demonstrated clinically meaningful reductions in NSSI; 6 participants responded to 1 intervention alone, whereas 2 participants responded after the addition of the alternative intervention. Group analyses indicated statistically significant overall effects of study phase on NSSI, with fewer NSSI urges and acts occurring after the interventions were introduced. The interventions were also associated with moderate to large reductions in self-reported levels of anxiety and depression, and large improvements in mindful emotion awareness and cognitive reappraisal skills.
CONCLUSIONS: Findings suggest that brief mindful emotion awareness and cognitive reappraisal interventions can lead to reductions in NSSI urges and acts. Transdiagnostic, emotion-focused therapeutic strategies delivered in time-limited formats may serve as practical yet powerful treatment approaches, especially for lower-risk self-injuring individuals.Dr. Barlow receives royalties from Oxford University Press, Guilford Publications Inc., Cengage Learning, and Pearson Publishing. Grant monies for various projects come from the National Institute of Mental Health (F31MH100761), the National Institute of Alcohol and Alcohol Abuse, and Colciencias (Government of Columbia Initiative for Science, Technology, and Health Innovation). Consulting and honoraria during the past several years have come from the Agency for Healthcare Research and Quality, the Foundation for Informed Medical Decision Making, the Department of Defense, the Renfrew Center, the Chinese University of Hong Kong, Universidad Catolica de Santa Maria (Arequipa, Peru), New Zealand Psychological Association, Hebrew University of Jerusalem, Mayo Clinic, and various American Universities. (F31MH100761 - National Institute of Mental Health; National Institute of Alcohol and Alcohol Abuse; Colciencias (Government of Columbia Initiative for Science, Technology, and Health Innovation))Accepted manuscrip
Electrophoretic separation of human kidney cells at zero gravity
Electrophoretic isolation of cells results in a loss of resolution power caused by the sedimentation of the cells in the media. The results of an experiment to extract urokinase from human embryos during the Apollo Soyuz mission are presented and discussed
An accident waiting to happen.
This piece was exhibited at the Kinetic Art Fair 2011 in London
Communications Biophysics
Contains reports on two research projects.United States Air Force (Contract AF19(604)-4112)United States National Institute of Neurological Diseases and Blindness, U.S. Public Health Service (BT-437)United States National Institute of Neurological Diseases and Blindness (B 369 Physiology)United States Navy, Office of Naval Research, (NR 101-445))United States Air Force, Office of Scientific Research (AF-49-(638)-98)
ENSO, Pacific Decadal Variability, and U.S. Summertime Precipitation, Drought, and Stream Flow
Upper estimate of martingale dimension for self-similar fractals
We study upper estimates of the martingale dimension of diffusion
processes associated with strong local Dirichlet forms. By applying a general
strategy to self-similar Dirichlet forms on self-similar fractals, we prove
that for natural diffusions on post-critically finite self-similar sets
and that is dominated by the spectral dimension for the Brownian motion
on Sierpinski carpets.Comment: 49 pages, 7 figures; minor revision with adding a referenc
Maser Source Finding Methods in HOPS
The {\bf H}{\bf O} Southern Galactic {\bf P}lane {\bf S}urvey (HOPS) has
observed 100 square degrees of the Galactic plane, using the Mopra radio
telescope to search for emission from multiple spectral lines in the 12\,mm
band (19.5\,--\,27.5\,GHz). Perhaps the most important of these spectral lines
is the 22.2\,GHz water maser transition. We describe the methods used to
identify water maser candidates and subsequent confirmation of the sources. Our
methods involve a simple determination of likely candidates by searching peak
emission maps, utilising the intrinsic nature of water maser emission -
spatially unresolved and spectrally narrow-lined. We estimate completeness
limits and compare our method with results from the {\sc Duchamp} source
finder. We find that the two methods perform similarly. We conclude that the
similarity in performance is due to the intrinsic limitation of the noise
characteristics of the data. The advantages of our method are that it is
slightly more efficient in eliminating spurious detections and is simple to
implement. The disadvantage is that it is a manual method of finding sources
and so is not practical on datasets much larger than HOPS, or for datasets with
extended emission that needs to be characterised. We outline a two-stage method
for the most efficient means of finding masers, using {\sc Duchamp}.Comment: 8 pages, 1 table, 4 figures. Accepted for publication in PASA special
issue on Source Finding & Visualisatio
Entropy and information in neural spike trains: Progress on the sampling problem
The major problem in information theoretic analysis of neural responses and
other biological data is the reliable estimation of entropy--like quantities
from small samples. We apply a recently introduced Bayesian entropy estimator
to synthetic data inspired by experiments, and to real experimental spike
trains. The estimator performs admirably even very deep in the undersampled
regime, where other techniques fail. This opens new possibilities for the
information theoretic analysis of experiments, and may be of general interest
as an example of learning from limited data.Comment: 7 pages, 4 figures; referee suggested changes, accepted versio
- …