Economic tomography: the possibility to anticipate and respond to socio-economic crises

The article discusses an approach based on an original hypothesis related to the peculiarities of Russia’s development (on the one hand, its scale, the Russian mentality and a certain closeness of the economy; on the other hand, a significant dominant resource and human potential, and, as a consequence, a genuine role in the global economic community), the diagnosis of which (at the level of the well-being of individuals and inhabited areas) can be used to identify crises, provide an early assessment of threats to socio-economic development of regions as well as help to evaluate the state of the region over a 3 to 5 year period. In other words, in order to ensure that executives have enough time to mount a sufficiently rapid response to the crises and administrative errors and to reduce the impact of emerging threats. The aim of this paper is to present theoretical and methodological tools for the recognition of the early stages of emerging threats, allowing fewer losses to be experienced during the crisis period. Simulation experiments were carried out for the purpose of classifying previously occurring social and economic crises (9 possible variants were reviewed) and mathematically processed trajectories of change in the main indicators for the well-being of individuals and inhabited areas, taking the influence of various factors into account. On the basis of the authors’ proposed approach (referred to as economic tomography) an attempt is made to comprehensively assess the state of sample representative regions of Russia.The research has been supported by the Russian Science Foundation (project № 14–18–00574 'Information-analytical system "Anticrisis:" diagnostics of the regions, threat assessment and scenario forecasting for the preservation and strengthening of economic security and well-being of Russia')

A 12 GHz satellite video receiver: Low noise, low cost prototype model for TV reception from broadcast satellites

A 12-channel synchronous phase lock video receiver consisting of an outdoor downconverter unit and an indoor demodulator unit was developed to provide both low noise performance and low cost in production quantities of 1000 units. The prototype receiver can be mass produced at a cost under $1540 without sacrificing system performance. The receiver also has the capability of selecting any of the twelve assigned satellite broadcast channels in the frequency range 11.7 to 12.2 GHz

SURGICAL CORRECTION OF INSUFFICIENCY OF CEREBRAL BLOOD FLOW AT THE ATHEROSCLEROSIS OF EXTRACEREBRAL ARTERIES

There is more than 1 million people who have had a stroke in Russia; the third part of these people are of working age, and only every fourth patient returned to job. This article discusses one of the most effective methods of stroke prevention - the procedure of carotid endarterectomy. We performed 468 reconstructive operations in 448 patients. 65 % (305) of surgeries were open carotid endarterectomies. In other cases, operations of prosthetics or blood flow switching between extracerebral arteries (ECA) (163) were carried out. Short-term results of reconstructive operations showed that 96 % of outcomes were positive. Perioperative mortality at operations made 1.06 %. The general complications made 4.5 %, minor complications were observed in 21 patients (4.4 %). The five years survival rate of patients operated on ECA made 86 %, the main cause of death in recent follow-up period was a cardiac pathology (58 %), brain disorders made 15 %. Among dominating risk factors are coronary heart disease, previous transient ischemic attacks and residual neurologic impairment

Safety of modified stair climbing test in the early period of rehabilitation of patients with acute myocardial infarction

Aim: safety evaluation of modified stair climbing test in the physical rehabilitation program for patients with old acute myocardial infarction. Materials and methods. Score of physical rehabilitation indices, its effectiveness and safety, comparison of physical rehabilitation indices of patients with AMI without reperfusion treatment and patients who had reperfusion interventions (bare-metal stents - in 21 persons, fibrinolysis - 1 patient, fibrinolysis and percutaneous coronary intervention - 1 patient) were estimated for 43 patients (6 women and 37 men) with old AMI using modified loading tests (stair climbing test and test with six-minute's walk). Results. HR (heart rate) fell short of submaximum values during modified stair climbing test in patient population. The condition was monitored using continuous ECG monitoring apparatus «Kardiotekhnika-04» (СС «Incart», Saint-Petersburg) None of patients showed ischemic changes of ST-segment. No significant differences were revealed in exercise tolerance between patients with old acute myocardial infarction with Q-wave who experienced stenting and patients with acute myocardial infarction without Q-wave. Results of six-minute's step test after the hospital rehabilitation stage completion show exercise tolerance increasing. Conclusion. Modified stair climbing test conducting for intensification of physical rehabilitation using subjective control was safe in examined patient population. According to six-minute's step test results, the exercise tolerance increased during rehabilitation process

Компьютерное моделирование светодиодного осветителя с фоконной оптикой для видеопроектора

Computer modeling and research of various variants of construction of light-diode illuminators for single-matrix LCD-video projector using inconsistent optical components are performed. The use of such components enables to form a light beam with the necessary parameters to align with the subsequent optical system. Computer modeling has allowed presents the analysis and evaluate the performance of the system developed in the design phase, and in some cases, and optimize it.Выполнено компьютерное моделирование и исследование различных вариантов построения светодиодных осветителей для одноматричного LCD-видеопроектора с использованием непоследовательных оптических компонентов. Применение таких компонентов позволяет сформировать световой пучок с необходимыми параметрами для согласования с последующей оптической системой. Компьютерное моделирование позволило проанализировать и оценить характеристики разрабатываемой системы на этапе проектирования, а в некоторых случаях и оптимизировать ее

A destabilized bacterial luciferase for dynamic gene expression studies

Fusions of genetic regulatory elements with reporter genes have long been used as tools for monitoring gene expression and have become a major component in synthetic gene circuit implementation. A major limitation of many of these systems is the relatively long half-life of the reporter protein(s), which prevents monitoring both the initiation and the termination of transcription in real-time. Furthermore, when used as components in synthetic gene circuits, the long time constants associated with reporter protein decay may significantly degrade circuit performance. In this study, short half-life variants of LuxA and LuxB from Photorhabdus luminescens were constructed in Escherichia coli by inclusion of an 11-amino acid carboxy-terminal tag that is recognized by endogenous tail-specific proteases. Results indicated that the addition of the C-terminal tag affected the functional half-life of the holoenzyme when the tag was added to luxA or to both luxA and luxB, but modification of luxB alone did not have a significant effect. In addition, it was also found that alteration of the terminal three amino acid residues of the carboxy-terminal tag fused to LuxA generated variants with half-lives of intermediate length in a manner similar to that reported for GFP. This report is the first instance of the C-terminal tagging approach for the regulation of protein half-life to be applied to an enzyme or monomer of a multi-subunit enzyme complex and will extend the utility of the bacterial luciferase reporter genes for the monitoring of dynamic changes in gene expression

Diagnostics case of tumorous stages of Kaposi's sarcoma in practice of the dermatovenerologist

The article is devoted to Kaposi's sarcoma, a system disease of vascular genesis, applied to tumors of mesenchyme tissue. Article provides frequency, prevalence, clinical manifestations, examples (occasions) of late - diagnosis. We describe a clinical case of this disease.Статья посвящена системному опухолевому заболеванию сосудистого генеза из числа новообразований дермы и подкожно-жировой клетчатки - саркоме Капоши. Рассмотрены вопросы частоты встречаемости заболевания, вариабельности клинической картины, своевременности постановки клинического диагноза. Описан клинический случай поздней диагностики данного заболевания

Experiment off diagnostics and treatment of primary cutaneous diffuse large В-cell lymphoma

The article provides a brief review of the literature about the incidence rate, classification, clinical manifestations, as well as modern methods of diagnostics and treatment of primary cutaneous diffuse large В-cell lymphomas. Here is also presented a case report.В статье представлен краткий обзор литературы о заболеваемости, классификации, клинических проявлениях, а также современных методах диагностики и лечения первичных кожных диффузных крупноклеточных В-клеточных лимфом. Описан клинический случай диагностики и лечения данной патологии