Bound states of magnons in the S=1/2 quantum spin ladder

We study the excitation spectrum of the two-leg antiferromagnetic S=1/2 Heisenberg ladder. Our approach is based on the description of the excitations as triplets above a strong-coupling singlet ground state. The quasiparticle spectrum is calculated by treating the excitations as a dilute Bose gas with infinite on-site repulsion. We find singlet (S=0) and triplet (S=1) two-particle bound states of the elementary triplets. We argue that bound states generally exist in any dimerized quantum spin model.Comment: 4 REVTeX pages, 4 Postscript figure

Understanding the Psychology of Gang Violence: Implications for Designing Effective Violence Reduction Interventions

An exploratory study to add to the understanding of the psychological processes contributing to violence carried out by gang members

Values of H_0 from Models of the Gravitational Lens 0957+561

The lensed double QSO 0957+561 has a well-measured time delay and hence is useful for a global determination of H0. Uncertainty in the mass distribution of the lens is the largest source of uncertainty in the derived H0. We investigate the range of \hn produced by a set of lens models intended to mimic the full range of astrophysically plausible mass distributions, using as constraints the numerous multiply-imaged sources which have been detected. We obtain the first adequate fit to all the observations, but only if we include effects from the galaxy cluster beyond a constant local magnification and shear. Both the lens galaxy and the surrounding cluster must depart from circular symmetry as well. Lens models which are consistent with observations to 95% CL indicate H0=104^{+31}_{-23}(1-\kthirty) km/s/Mpc. Previous weak lensing measurements constrain the mean mass density within 30" of G1 to be kthirty=0.26+/-0.16 (95% CL), implying H0=77^{+29}_{-24}km/s/Mpc (95% CL). The best-fitting models span the range 65--80 km/s/Mpc. Further observations will shrink the confidence interval for both the mass model and \kthirty. The range of H0 allowed by the full gamut of our lens models is substantially larger than that implied by limiting consideration to simple power law density profiles. We therefore caution against use of simple isothermal or power-law mass models in the derivation of H0 from other time-delay systems. High-S/N imaging of multiple or extended lensed features will greatly reduce the H0 uncertainties when fitting complex models to time-delay lenses.Comment: AASTEX, 48 pages 4 figures, 2 tables. Also available at: http://www.astro.lsa.umich.edu:80/users/philf/www/papers/list.htm

Leveraging agrobiodiversity to create sustainable food systems for healthier diets

The current ways that planetary resources are used to produce and consume food are raising significant concerns about the impact on nutrition, health and sustainability. A major reorientation of our food systems is needed in terms of both activities and governance. This paper describes the important contributions agricultural biodiversity makes achieving healthy diets and sustainable food systems and highlights a number of key actions needed to maximize those contributions. Dietary factors are the number one risk factor in the global burden of disease. At the same time, many of the ways in which food systems operate, from production to sales and consumption, are causing significant environmental damage, including loss of biodiversity and of the beneficial services that biodiversity in ecosystems provides to humanity. This paper argues that focusing on increasing agricultural biodiversity in landscapes, food systems and diets is an important part of the solution to creating healthier diets from sustainable food systems. For instance, a healthy diet should be based on whole grains, fruit, vegetables, legumes, nuts and seeds, and be limited in added sugar and sodium. Agrobiodiversity can ensure these essential ingredients are present in our food system, and so support healthy diets. In terms of increased sustainability of food systems, agricultural biodiversity can boost yields, provide pollination services and pest and disease control, reduce the need for inorganic fertilizers and synthetic pesticides, and provide protection to natural habitats. Agrobiodiversity can also contribute to breeding of crops and animals that are more capable of coping with climate change. Good governance is key to achieving positive outcomes from promotion of agrobiodiversity. Food systems arise from complex agronomic, economic, political, institutional and social interrelationships. Good governance must drive the enabling environment that influences multiple actors operating in these systems and the actions they can take that will impact on the sustainability of food systems and the creation of healthy diets. Promoting agricultural biodiversity can be a practical investment for healthier diets through four main avenues: local and more nutritious value chains; public or institutional procurement; increased availability of fruits and vegetables; and appropriate policy incentives and coherence for diversification of production and consumption. We use examples from a number of contexts to illustrate potential actions that other countries may follow

The ZO-1–associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density

Epithelial tight junctions regulate paracellular permeability, restrict apical/basolateral intramembrane diffusion of lipids, and have been proposed to participate in the control of epithelial cell proliferation and differentiation. Previously, we have identified ZO-1–associated nucleic acid binding proteins (ZONAB), a Y-box transcription factor whose nuclear localization and transcriptional activity is regulated by the tight junction–associated candidate tumor suppressor ZO-1. Now, we found that reduction of ZONAB expression using an antisense approach or by RNA interference strongly reduced proliferation of MDCK cells. Transfection of wild-type or ZONAB-binding fragments of ZO-1 reduced proliferation as well as nuclear ZONAB pools, indicating that promotion of proliferation by ZONAB requires its nuclear accumulation. Overexpression of ZONAB resulted in increased cell density in mature monolayers, and depletion of ZONAB or overexpression of ZO-1 reduced cell density. ZONAB was found to associate with cell division kinase (CDK) 4, and reduction of nuclear ZONAB levels resulted in reduced nuclear CDK4. Thus, our data indicate that tight junctions can regulate epithelial cell proliferation and cell density via a ZONAB/ZO-1–based pathway. Although this regulatory process may also involve regulation of transcription by ZONAB, our data suggest that one mechanism by which ZONAB and ZO-1 influence proliferation is by regulating the nuclear accumulation of CDK4

Boosting jet power in black hole spacetimes

The extraction of rotational energy from a spinning black hole via the Blandford-Znajek mechanism has long been understood as an important component in models to explain energetic jets from compact astrophysical sources. Here we show more generally that the kinetic energy of the black hole, both rotational and translational, can be tapped, thereby producing even more luminous jets powered by the interaction of the black hole with its surrounding plasma. We study the resulting Poynting jet that arises from single boosted black holes and binary black hole systems. In the latter case, we find that increasing the orbital angular momenta of the system and/or the spins of the individual black holes results in an enhanced Poynting flux.Comment: 7 pages, 5 figure

An investigation into the feasibility of myoglobin-based single-electron transistors

Myoglobin single-electron transistors were investigated using nanometer- gap platinum electrodes fabricated by electromigration at cryogenic temperatures. Apomyoglobin (myoglobin without heme group) was used as a reference. The results suggest single electron transport is mediated by resonant tunneling with the electronic and vibrational levels of the heme group in a single protein. They also represent a proof-of-principle that proteins with redox centers across nanometer-gap electrodes can be utilized to fabricate single-electron transistors. The protein orientation and conformation may significantly affect the conductance of these devices. Future improvements in device reproducibility and yield will require control of these factors