1,235 research outputs found
Evaluation of the institutional structure of sustainable forest management in the Netherlands
Kwantificeren van recente veranderingen in status van amfibieën en hun biotopen in het landelijk gebied: evaluatie en niet-technische samenvatting
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Introduction: Key Issues in the Sociology of Intellectuals
This chapter offers some preliminary reflections on Simon Susen and Patrick Baert’s The Sociology of Intellectuals: After ‘The Existentialist Moment’ (Basingstoke: Palgrave Macmillan, 2017). The chapter emphasizes three principal objectives of this book: first, to explore a new set of conceptual and methodological tools for the sociology of intellectuals (theoretical level); second, to assess how the phenomenon of the public intellectual has altered since the beginning of the twentieth century (historical level); and, third, to examine the extent to which intellectuals can play a constructive role in influencing social and political developments in the modern era (normative level). The chapter goes on to give a brief overview of both the structure and the contents of the book. Finally, the chapter explains why, in light of recent social and political transformations, the challenge of providing a theoretical framework for the sociological study of intellectuals has become particularly pressing
Differential roles of p39Mos–Xp42Mpk1 cascade proteins on Raf1 phosphorylation and spindle morphogenesis in Xenopus oocytes
AbstractFully-grown G2-arrested Xenopus oocytes resume meiosis upon hormonal stimulation. Resumption of meiosis is characterized by germinal vesicle breakdown, chromosome condensation, and organization of a bipolar spindle. These cytological events are accompanied by activation of MPF and the p39Mos–MEK1–Xp42Mpk1–p90Rsk pathways. The latter cascade is activated upon p39Mos accumulation. Using U0126, a MEK1 inhibitor, and p39Mos antisense morpholino and phosphorothioate oligonucleotides, we have investigated the role of the members of the p39Mos–MEK1–Xp42Mpk1–p90Rsk in spindle morphogenesis. First, we have observed at a molecular level that prevention of p39Mos accumulation always led to MEK1 phosphorylation defects, even when meiosis was stimulated through the insulin Ras-dependent pathway. Moreover, we have observed that Raf1 phosphorylation that occurs during meiosis resumption was dependent upon the activity of MEK1 or Xp42Mpk1 but not p90Rsk. Second, inhibition of either p39Mos accumulation or MEK1 inhibition led to the formation of a cytoplasmic aster-like structure that was associated with condensed chromosomes. Spindle morphogenesis rescue experiments using constitutively active Rsk and purified murine Mos protein suggested that p39Mos or p90Rsk alone failed to promote meiotic spindle organization. Our results indicate that activation of the p39Mos–MEK1–Xp42Mpk1–p90Rsk pathway is required for bipolar organization of the meiotic spindle at the cortex
Observation of Vortex Matching Phenomena in Antidot Array of NbN Thin Film
We report vortex matching phenomenon in rectangular antidot array fabricated
on epitaxial NbN thin film. The antidot array was fabricated using Focussed Ion
Beam milling technique. The magneto-transport measurements points to a period
doubling transition at higher magnetic field for rectangular lattices. The
results are discussed within the light of several models including the
multi-vortex model, the matched lattice model and the super-matched lattice
model.Comment: Added references, modified abstract and discussions and corrected
typo-graphic errors. Accepted for proceedings of M2S-IX 2009, Tokyo (Physica
C
Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis
PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.PMCID: PMC385649
Frustration and Melting of Colloidal Molecular Crystals
Using numerical simulations we show that a variety of novel colloidal
crystalline states and multi-step melting phenomena occur on square and
triangular two-dimensional periodic substrates. At half-integer fillings
different kinds of frustration effects can be realized. A two-step melting
transition can occur in which individual colloidal molecules initially rotate,
destroying the overall orientational order, followed by the onset of interwell
colloidal hopping, in good agreement with recent experiments.Comment: 6 pages, 3 postscript figures. Procedings of International Conference
on Strongly Coupled Coulomb Systems, Santa Fe, 200
Multiply quantized vortices in trapped Bose-Einstein condensates
Vortex configurations in rotating Bose-Einstein condensed gases trapped in
power-law and anharmonic potentials are studied. When the confining potential
is steeper than harmonic in the plane perpendicular to the axis of rotation,
vortices with quantum numbers larger than one are energetically favorable if
the interaction is weak enough. Features of the wave function for small and
intermediate rotation frequencies are investigated numerically.Comment: 9 pages, 6 figures. Revised and extended article following referee
repor
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Variational guidewire tracking using phase congruency
We present a novel method to track a guidewire in cardiac x-ray video. Using variational calculus, we derive differential equations that deform a spline, subject to intrinsic and extrinsic forces, so that it matches the image data, remains smooth, and preserves an a priori length. We analytically derive these equations from first principles, and show how they include tangential terms, which we include in our model. To address the poor contrast often observed in x-ray video, we propose using phase congruency as an image-based feature. Experimental results demonstrate the success of the method in tracking guidewires in low contrast x-ray video
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