Storage stability of encapsulated barberry's anthocyanin and its application in jelly formulation

The barberry (Berberis vulgaris) extract which is a rich source of anthocyanin was used for encapsulation with three different wall materials i.e., combination of gum Arabic and maltodextrin (GA+MD), combination of maltodextrin and gelatin (MD+GE) and maltodextrin (MD) by spray drying process. In this context, the storage stability of encapsulated pigments was investigated under four storage temperatures (4, 25, 35 and 42 °C), four relative humidities (20, 30, 40 and 50%) and light illumination until 90 days. All wall materials largely increased the half-life of the encapsulated pigments during storage compared with non-encapsulated anthocyanins. MD+GA showed the highest encapsulation efficiency, lower degradation rate in all temperatures and was found as the most effective wall material in stabilizing the pigments. The encapsulated pigments were utilized in coloring jelly powder as an alternative of synthetic color. Sensory evaluation were run to identify best encapsulated natural color concentration in jelly powder formulation according to acceptability by consumers. A jelly with added 7% encapsulated color had higher scores than the commercial jelly containing synthetic color for all the sensory attributes evaluated. Physicochemical properties of produced jelly including moisture content, hygroscopicity, acidity, ash content and texture were not significantly different with control sample while, syneresis and solubility of the samples prepared with encapsulated color was significantly reduced. © 2016 Elsevier Ltd

Microencapsulation optimization of natural anthocyanins with maltodextrin, gum Arabic and gelatin

The barberry (Berberis vulgaris) extract which is a rich source of anthocyanins was used for spray drying encapsulation with three different wall materials, i.e., combination of maltodextrin and gum Arabic (MD + GA), maltodextrin and gelatin (MD + GE), and maltodextrin (MD). Response Surface Methodology (RSM) was applied for optimization of microencapsulation efficiency and physical properties of encapsulated powders considering wall material type as well as different ratios of core to wall materials as independent variables. Physical characteristics of spray-dried powders were investigated by further analyses of moisture content, hygroscopicity, degree of caking, solubility, bulk and absolute density, porosity, flowability and microstructural evaluation of encapsulated powders. Our results indicated that samples produced with MD + GA as wall materials represented the highest process efficiency and best powder quality; the optimum conditions of microencapsulation process for barberry anthocyanins were found to be the wall material content and anthocyanin load of 24.54 and 13.82, respectively. Under such conditions, the microencapsulation efficiency (ME) of anthocyanins could be as high as 92.83. © 2016 Elsevier B.V

The Development of explosives competencies, training and education in the UK

Competent explosives workers in the Armed Forces and in the civil sector are critical to the safe production, testing and use of explosives. Moreover we need competent explosives specialists to combat the challenge from terrorism and clean up the planet from the explosive hazards that are the legacy of past conflicts. Unfortunately many countries are witnessing a significant loss of capability in this area and are looking at ways of replenishing vital expertise. This paper describes the work done in recent years by the authors and others in the UK to establish numbers of people working in the sector and to consider the skills and knowledge required to carry out their work. It outlines the concept of national occupational standards and the framework of professional and vocational qualifications that are available or are being developed for explosives specialists. It also describes some of the educational and e-learning programmes designed to support this initiative. Ultimately the aim is to address the professionalism of all personnel who deal with explosives in order to reduce the incidence and consequence of accidents and maintain national capability

Diagnostic values of serum levels of pepsinogens and gastrin-17 for screening gastritis and gastric cancer in a high risk area in Northern Iran

Background: Gastric cancer (GC) is the second cause of cancer related death in the world. It may develop by progression from its precancerous condition, called gastric atrophy (GA) due to gastritis. The aim of this study was to evaluate the accuracy of serum levels of pepsinogens (Pg) and gastrin-17 (G17) as non-invasive methods to discriminate GA or GC (GA/GC) patients. Materials and Methods: Subjects referred to gastrointestinal clinics of Golestan province of Iran during 2010 and 2011 were invited to participate. Serum levels of PgI, PgII and G17 were measured using a GastroPanel kit. Based on the pathological examination of endoscopic biopsy samples, subjects were classified into four groups: normal, non-atrophic gastritis, GA, and GC. Receiver operating curve (ROC) analysis was used to determine cut-off values. Indices of validity were calculated for serum markers. Results: Study groups were normal individuals (n=74), non-atrophic gastritis (n=90), GA (n=31) and GC patients (n=30). The best cut-off points for PgI, PgI/II ratio, G17 and HP were 80 μg/L, 10, 6 pmol/L, and 20 EIU, respectively. PgI could differentiate GA/GC with high accuracy (AUC=0.83; 95%CI: 0.76-0.89). The accuracy of a combination of PgI and PgI/II ratio for detecting GA/GC was also relatively high (AUC=0.78; 95%CI: 0.70-0.86). Conclusions: Our findings suggested PgI alone as well as a combination of PgI and PgI/II ratio are valid markers to differentiate GA/GC. Therefore, Pgs may be considered in conducting GC screening programs in high-risk areas

Spectral analysis perspective of why misinformation containment is still an unsolved problem

Misinformation is still a major societal problem. The arrival of ChatGPT only added to the problem. This paper analyzes misinformation in the form of text from a spectral analysis perspective to find the answer to why the problem is still unsolved despite multiple years of research and a plethora of solutions in the literature. A variety of embedding techniques are used to represent information for the purpose. The diverse spectral methods used on these embeddings include t-distributed Stochastic Neighbor Embedding (t-SNE) and Principal Component Analysis (PCA). The analysis shows that misinformation is quite closely intertwined with genuine information and the machine learning algorithms are not as effective in separating the two despite the claims in the literature

Breaking a Chaotic Cryptographic Scheme Based on Composition Maps

Recently, a chaotic cryptographic scheme based on composition maps was proposed. This paper studies the security of the scheme and reports the following findings: 1) the scheme can be broken by a differential attack with $6+\lceil\log_L(MN)\rceil$ chosen-plaintext, where $MN$ is the size of plaintext and $L$ is the number of different elements in plain-text; 2) the scheme is not sensitive to the changes of plaintext; 3) the two composition maps do not work well as a secure and efficient random number source.Comment: 9 pages, 7 figure

Efficacy and Safety of Lamotrigine in Lennox - Gastaut Syndrome

ObjectiveThe Lennox-Gastaut syndrome (LGS), one of the most difficult epilepsy syndromes to treat, is characterized by a triad of intractable seizures of various types, a slow (< 2.5-hertz) spike-wave pattern in EEG and mental retardation. The aim of this study was to evaluate the efficacy and safety of lamotrigine as add-on therapy in intractable epilepsy of children with LGS.Materials & MethodsIn a quasi- experimental study, 40 children with LGS referred to the pediatric neurology clinic of Shaheed Sadoughi Hospital in Yazd, between August 2007 and to November 2008, were evaluated.ResultsTwenty-two boys and 18 girls with a mean age of 4.12 ±1.8 years were evaluated. At the end of three months of treatment with lamotrigine, 12 % were seizure free, 52% had> 50% reduction in seizure frequency and 12% had increase in seizures. Means of seizure frequency/per week, before and after treatment were 70 (range 1-180) and 18.6 (range 0-60) respectively, indicating effectiveness of the drug in seizure reduction (P value = 0.003). The drug was effective in 72 % of mixed type seizures, 40 % of generalized tonic-clonic and 33% of drop attack and tonic seizures. Transient side effects were seen in 12.5 % (drowsiness in 3 and ataxia in 2 children). No serious side effects were seen.ConclusionLamotrigine should be considered as an add-on therapy in management of intractable epilepsy in LGS

Plasmonic light-sensitive skins of nanocrystal monolayers

Cataloged from PDF version of article.We report plasmonically coupled light-sensitive skins of nanocrystal monolayers that exhibit sensitivity enhancement and spectral range extension with plasmonic nanostructures embedded in their photosensitive nanocrystal platforms. The deposited plasmonic silver nanoparticles of the device increase the optical absorption of a CdTe nanocrystal monolayer incorporated in the device. Controlled separation of these metallic nanoparticles in the vicinity of semiconductor nanocrystals enables optimization of the photovoltage buildup in the proposed nanostructure platform. The enhancement factor was found to depend on the excitation wavelength. We observed broadband sensitivity improvement (across 400-650 nm), with a 2.6-fold enhancement factor around the localized plasmon resonance peak. The simulation results were found to agree well with the experimental data. Such plasmonically enhanced nanocrystal skins hold great promise for large-area UV/visible sensing applications