High prevalence of double Plasmodium falciparum dhfr mutations at codons 108 and 59 in the Sistan-Baluchistan province, Iran

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Neonatal Seizure: Etiology and Type

ObjectiveNeonates, for many reasons, are at particular risk for the development of seizures, which are a strong predictor of later morbidity and mortality in infants.We undertook this study to determine the incidence, etiologic distribution and neonatal seizure type in neonates with hospital admission over a period of 4 years.Materials and MethodsThis, a retrospective study of newborns admitted in hospital with a diagnosis of neonatal seizures, was conducted over a 4 year period between March 2001 and March 2005.Data were obtained from hospital records was analyzed using the Chi-square test.ResultsOf 4541 newborns, admitted to hospital, during the study period, seizures occurred in 110 neonates. The incidence of neonatal seizures was 2.4%; the causes of neonatal seizure were Hypoxic-Ischemic Encephalopathy (HIE) - 36.4%, infections -19.1%, metabolic abnormalities - 7.3%, Intra Cranial Hemorrhage (ICH) - 2.7%, structural disorders - 1.8% and in 32.7% of cases, the cause was unknown.Subtle seizures (39.1%) were the most common type of seizures; and the other types were myoclonic (17.3%), clonic (10.0%), Tonic (7.3%), Generalized Tonic Clonic Seizures (GTCS) (12.7%) and in 13.6% of cases the type of seizure was not mentioned. Mortality rate was 13.6%.ConclusionHealth care workers and parents need to be made aware of subtle seizures and the importance of timely and appropriate treatment to decrease any further complications

A note on quasi-Gorenstein rings

In this paper, after giving a criterion for a Noetherian local ring to be quasi-Gorenstein, we obtain some sufficient conditions for a quasi- Gorenstein ring to be Gorenstein. In the course, we provide a slight generalization of a theorem of Evans and Griffith.Comment: To appear in Arch. Mat