175 research outputs found
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The impact of heavy (excessive) video gaming students on peers and teachers in the school environment: a qualitative study
Video gaming has now become very popular among children and adolescents. Because of the increasing use of videogames, the debate concerning the effects of video games has been ongoing, particularly in terms of gamersā social lives. This study explores the impact of heavy gaming students on their peers and teachers in the school environment. For this purpose, focus-group and face-to-face interviews have been carried out using semi-structured interview forms developed by the research team. The data have been collected from 21 participants comprised of three heavy gaming students, 16 peers, and two teachers. The findings indicate heavy gamers to display problematic behaviors including communication and behavioral problems within the school environment. Results also show heavy gaming students to prefer staying at home and playing videogames rather than attending school activities. Heavy gamers mostly prefer spending time with other heavy gamers or with male peers because they have mutual topics they can talk about (video games, their game talents, soccer, outdoor games etc.), which they are unable to with girls. According to the teachers, heavy gamers have low-school performance. However, the English teacher emphasized the positive effects of video gaming on students' English vocabulary
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Comparison of value perception of children in playing videogames and traditional games: Turkish and British samples
The present study examined the value perceptions of Turkish and British children according to various variables and determined to what extent traditional and videogame genres preferred by children predict their value perceptions, dominant case design, one of the mixed research designs, was used. While the quantitative approach was mainly used in the research, the qualitative approach was used as a supporter. The data collection process of the study lasted for two academic years. In the first year, the study was conducted with 243 primary school students studying in Nottingham (England). In the following year it was conducted with 267 primary school students studying in Ankara (Turkey). A total of 510 primary school students with ages ranging from 9-11 years were recruited for the study. Data were collected using the āPersonal Information Formā and āMoral Dilemma Stories Inventory for Childrenā. Both were developed in English and then adapted into Turkish. It was found that, in both sample, girlsā value perception scores were significantly higher than boysā scores. Videogames primarily produced for entertainment were the most preferred games by Turkish and British children while educational and serious videogames were the least preferred. Traditional games in sports (soccer, cricket, etc.) were preferred more by British children, while traditional action games (dodgeball, playing tag etc.) were preferred more by Turkish children. It was found that action-adventure and role-playing videogames predicted childrenās value perception negatively, and simulation and puzzle videogame genres predicted childrenās value perceptions positively. Furthermore, movement-based traditional games (sports, action) predicted childrenās value perceptions positively, while traditional competitive (racing) games predicted childrenās value perceptions negatively
Efficacy, safety, tolerability and pharmacokinetics of a novel human immune globulin subcutaneous, 20%: a Phase 2/3 study in Europe in patients with primary immunodeficiencies
A highly concentrated (20%) immunoglobulin (Ig)G preparation for subcutaneous administration (IGSC 20%), would offer a new option for antibody replacement therapy in patients with primary immunodeficiency diseases (PIDD). The efficacy, safety, tolerability and pharmacokinetics of IGSC 20% were evaluated in a prospective trial in Europe in 49 patients with PIDD aged 2-67 years. Over a median of 358 days, patients received 2349 IGSC 20% infusions at monthly doses equivalent to those administered for previous intravenous or subcutaneous IgG treatment. The rate of validated acute bacterial infections (VASBIs) was significantly lower than 1 per year (0.022/patient-year, P /= 8 g/l. There was no serious adverse event (AE) deemed related to IGSC 20% treatment; related non-serious AEs occurred at a rate of 0.101 event/infusion. The incidence of local related AEs was 0.069 event/infusion (0.036 event/infusion, when excluding a 13-year-old patient who reported 79 of 162 total related local AEs). The incidence of related systemic AEs was 0.032 event/infusion. Most related AEs were mild, none were severe. For 64.6% of patients and in 94.8% of IGSC 20% infusions, no local related AE occurred. The median infusion duration was 0.95 (range = 0.3-4.1) h using mainly one to two administration sites [median = 2 sites (range = 1-5)]. Almost all infusions (99.8%) were administered without interruption/stopping or rate reduction. These results demonstrate that IGSC 20% provides an effective and well-tolerated therapy for patients previously on intravenous or subcutaneous treatment, without the need for dose adjustment
Cigarette smoking and tuberculosis in Cambodia: findings from a national sample
Background
Cambodia has very high rates of tuberculosis and smoked tobacco use among adults. Efforts to control both tobacco use and tuberculosis in Cambodia need to be informed by nationally representative data. Our objective is to examine the relation between daily cigarette smoking and lifetime tuberculosis (TB) history in a national sample of adults in Cambodia.
Methods
In 2011, a multi-stage, cluster sample of 15,615 adults (ages 15āyears and older) from all regions of Cambodia were administered the Global Adult Tobacco Survey by interviewers from the National Institute of Statistics of Cambodia.
Results
Our findings include: 1) among daily smokers, a significant positive relation between TB and number of cigarettes smoked per day (ORā=ā1.70 [95% CI 1.01, 2.87]) and pack-years of smoking (ORā=ā1.53 [95% CI 1.05, 2.25]) 2) a non-significant 58% increase in odds of ever having being diagnosed with TB among men who smoked manufactured cigarettes (ORā=ā1.58 [95% CI 0.97, 2.58]).
Conclusions
In Cambodia, manufactured cigarette smoking was associated with lifetime TB infection and the association was most evident among the heaviest smokers (> 1 pack per day, > 30 pack years)
Cutaneous infection by Mycobacterium haemophilum and kansasii in an IgA-deficient man
<p>Abstract</p> <p>Background</p> <p>The prevalence of infections by nontuberculous mycobacteria (NTM) has steadily increased over the past decades, especially in immunocompromised patients.</p> <p>Case presentation</p> <p>We present a patient with IgA-deficiency and mixed cutaneous infection by two slowly growing mycobacteria, <it>Mycobacterium </it>(<it>M.</it>) <it>haemophilum </it>and <it>M. kansasii.</it></p> <p>Conclusions</p> <p>Cutaneous <it>M. haemophilum </it>infections most often result from HIV or transplantation-associated immunosuppression. Rarely, <it>M. haemophilum </it>may also infect healthy patients or iatrogenically immunosuppressed patients without transplantation. <it>M. kansasii </it>is one of the most frequent NTM and large awareness exists about its involvement in human diseases. Mycobacterial diagnosis of cutaneous infections should be considered in long-lasting skin lesions.</p
Serum Adipocyte Fatty AcidāBinding Protein Levels Are Associated With Nonalcoholic Fatty Liver Disease in Type 2 Diabetic Patients
OBJECTIVEāAdipocyte fatty acidābinding protein (A-FABP) is a major cytoplasmic protein in adipocytes and macrophages and is closely associated with metabolic syndrome, type 2 diabetes, and atherosclerosis. Here, we investigated whether A-FABP was associated with nonalcoholic fatty liver disease (NAFLD) in type 2 diabetes
Value of minimum intensity projections for chest CT in COVID-19 patients
Purpose: To investigate whether minimum intensity projection (MinIP) reconstructions enable more accurate depiction of pulmonary ground-glass opacity (GGO) compared to standard transverse sections and multiplanar reformat (MPR) series in patients with suspected coronavirus disease 2019 (COVID-19). Method: In this multinational study, chest CT scans of 185 patients were retrospectively analyzed. Diagnostic accuracy, diagnostic confidence, image quality regarding the assessment of GGO, as well as subjective time-efficiency of MinIP and standard MPR series were analyzed based on the assessment of six radiologists. In addition, the suitability for COVID-19 evaluation, image quality regarding GGO and subjective time-efficiency in clinical routine was assessed by five clinicians. Results: The reference standard revealed a total of 149 CT scans with pulmonary GGO. MinIP reconstructions yielded significantly higher sensitivity (99.9 % vs 95.6 %), specificity (95.8 % vs 86.1 %) and accuracy (99.1 % vs 93.8 %) for assessing of GGO compared with standard MPR series. MinIP reconstructions achieved significantly higher ratings by radiologists concerning diagnostic confidence (medians, 5.00 vs 4.00), image quality (medians, 4.00 vs 4.00), contrast between GGO and unaffected lung parenchyma (medians, 5.00 vs 4.00) as well as subjective time-efficiency (medians, 5.00 vs 4.00) compared with MPR-series (all P <.001). Clinicians preferred MinIP reconstructions for COVID-19 assessment (medians, 5.00 vs 3.00), image quality regarding GGO (medians, 5.00 vs 3.00) and subjective time-efficiency in clinical routine (medians, 5.00 vs 3.00). Conclusions: MinIP reconstructions improve the assessment of COVID-19 in chest CT compared to standard images and may be suitable for routine application
Ab-initio structural, elastic, and vibrational properties of carbon nanotubes
A study based on ab initio calculations is presented on the estructural,
elastic, and vibrational properties of single-wall carbon nanotubes with
different radii and chiralities. We use SIESTA, an implementation of
pseudopotential-density-functional theory which allows calculations on systems
with a large number of atoms per cell. Different quantities like bond
distances, Young moduli, Poisson ratio and the frequencies of different phonon
branches are monitored versus tube radius. The validity of expectations based
on graphite is explored down to small radii, where some deviations appear
related to the curvature effects. For the phonon spectra, the results are
compared with the predictions of the simple zone-folding approximation. Except
for the known defficiencies of this approximation in the low-frequency
vibrational regions, it offers quite accurate results, even for relatively
small radii.Comment: 13 pages, 7 figures, submitted to Phys. Rev. B (11 Nov. 98
Atypical X-linked agammaglobulinaemia caused by a novel BTK mutation in a selective immunoglobulin M deficiency patient
Coracoid impingement syndrome: a literature review
Coracoid impingement syndrome is a less common cause of shoulder pain. Symptoms are presumed to occur when the subscapularis tendon impinges between the coracoid and lesser tuberosity of the humerus. Coracoid impingement should be included in the differential diagnosis when evaluating a patient with activity-related anterior shoulder pain. It is not thought to be as common as subacromial impingement, and the possibility of the coexistence of the two conditions must be taken into consideration before treatment of either as an isolated process. If nonoperative treatment fails to relieve symptoms, surgical decompression can be offered as an option
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