289 research outputs found

    FPGA Implementation of a Frame Synchronization Algorithm for Powerline Communications

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    This paper presents an FPGA implementation of a pilot–based time synchronization scheme employing orthogonal frequency division multiplexing for powerline communication channels. The functionality of the algorithm is analyzed and tested over a real powerline residential network. For this purpose, an appropriate transmitter circuit, implemented by an FPGA, and suitable coupling circuits are constructed. The system has been developed using VHDL language on Nallatech XtremeDSP development kits. The communication system operates in the baseband up to 30 MHz. Measurements of the algorithm's good performance in terms of the number of detected frames and timing offset error are taken and compared to simulations of existing algorithms

    A MMIC QPSK Modulator

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    In this paper a MMIC QPSK modulator is described. The bit rate of the baseband signal is 155 Mbits/sec, while the frequency of the carrier is fLO=10 GHz . The modulation is performed directly at the RF band and therefore an IF stage is not necessary. The design contains all the necessary sub-circuits except for the demultiplexer and the low-pass filters, which are used so that the bandwidth of the binary waves can be reduced. The mixers that are contained in the circuit are not the typical Gilbert cells and as a result they occupy a much smaller area (half). The circuit needs no external LO coupler and no RF chocks. The F-20 process of GEC Marconi was used for designing the modulator. The occupied area is approximately 12 mm2 . Section 1 presents fundamentals on Quadriphase Shift Keying (QPSK), while in Section 2 the characteristics of the F-20 process are described. In the following Sections the sub-circuits, the complete circuit, and its simulated results are presented

    Behavioral and brain pattern differences between acting and observing in an auditory task

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    <p>Abstract</p> <p>Background</p> <p>Recent research has shown that errors seem to influence the patterns of brain activity. Additionally current notions support the idea that similar brain mechanisms are activated during acting and observing. The aim of the present study was to examine the patterns of brain activity of actors and observers elicited upon receiving feedback information of the actor's response.</p> <p>Methods</p> <p>The task used in the present research was an auditory identification task that included both acting and observing settings, ensuring concurrent ERP measurements of both participants. The performance of the participants was investigated in conditions of varying complexity. ERP data were analyzed with regards to the conditions of acting and observing in conjunction to correct and erroneous responses.</p> <p>Results</p> <p>The obtained results showed that the complexity induced by cue dissimilarity between trials was a demodulating factor leading to poorer performance. The electrophysiological results suggest that feedback information results in different intensities of the ERP patterns of observers and actors depending on whether the actor had made an error or not. The LORETA source localization method yielded significantly larger electrical activity in the supplementary motor area (Brodmann area 6), the posterior cingulate gyrus (Brodmann area 31/23) and the parietal lobe (Precuneus/Brodmann area 7/5).</p> <p>Conclusion</p> <p>These findings suggest that feedback information has a different effect on the intensities of the ERP patterns of actors and observers depending on whether the actor committed an error. Certain neural systems, including medial frontal area, posterior cingulate gyrus and precuneus may mediate these modulating effects. Further research is needed to elucidate in more detail the neuroanatomical and neuropsychological substrates of these systems.</p

    Mismatch task conditions and error related ERPs

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    <p>Abstract</p> <p>Background</p> <p>The N200 component of event related potentials (ERPs) is considered an index of monitoring error related responses. The aim of the present work was to study the effect of mismatch conditions on the subjects' responses in an auditory identification task and their relation to the N200 of stimulus-locked ERPs.</p> <p>Methods</p> <p>An auditory identification task required to correctly map a horizontal slider onto an active frequency range by selecting a slider position that matched the stimulus tone in each trial. Fourteen healthy volunteers participated in the study and ERPs were recorded by 32 leads.</p> <p>Results</p> <p>Results showed that the subjects' erroneous responses were equally distributed within trials, but were dependent on mismatch conditions, generated by large differences between the frequencies of the tones of consecutive trials. Erroneous trials showed a significantly greater negativity within the time window of 164-191 ms after stimulus, located mainly at the Cz and Fz electrodes. The LORETA solution showed that maximum activations, as well as maximum differences, were localized mainly at the frontal lobe.</p> <p>Conclusions</p> <p>These findings suggest that the fronto-central N200 component, conceived an index of "reorientation of attention", represents a correlate of an error signal, being produced when representation of the actual response and the required response are compared. Furthermore the magnitude of the amplitude of the N200 rests on the relation between the present and the previous stimulus.</p

    The effect of racemic gossypol and AT-101 on angiogenic profile of OVCAR-3 cells: a preliminary molecular framework for gossypol enantiomers

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    To compare the effect of racemic gossypol with its (–)/(–) enantiomer (AT-101) on expression profiles of angiogenic molecules by mRNA levels in human ovarian cancer cell line OVCAR-3. Methods: Cell viability assay (2,3-bis (2-methoxy-4-nitro-5- sulfophenyl)-5-[(phenylamino) carbonyl]-2H-tetrazolium hydroxide) was used to detect cytotoxicity of gossypol enantiomers. DNA fragmentation by an enzyme-linked immunosorbent (ELISA) assay was used to evaluate the rate of apoptosis. The mRNA expression levels of angiogenic molecules were investigated by Human Angiogenesis RT2 ProfilerTM PCR Array (SuperArray, Frederick, MD). Results: Both racemic form and AT-101 resulted in a significant cytotoxicity and induced apoptosis. This effect was observed in a dose- and time dependent manner. However, AT-101 was much more potent. In addition, the treatment of 10 μM of racemic gossypol alone and 3 μM of AT-101 alone resulted in significant down-regulation (≥ 3 fold) in mRNA levels of some pivotal angiogenic molecules in OVCAR-3, but altered gene profiles were different by the treatment of each enantiomer. Conclusion: The efficacy of two gossypol enantiomers in OVCAR-3 cells showed distinction. AT-101 was much more potent than racemic gossypol, not only by means of cell death and apoptosis, but also by modulation of angiogenic molecules released from OVCAR-3 cells. Further studies with endothelial cells should be done to verify the anti-angiogenic effect of gossypol enantiomers in cancer treatment
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