In Vivo Observation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of Abuse

Catecholaminergic (dopamine and norepinephrine) projections to the cortex play an important role in cognitive functions and dysfunctions including learning, addiction, and mental disorders. While dynamics of glutamatergic synapses have been well studied in such contexts, little is known regarding catecholaminergic projections, owing to lack of robust methods. Here we report a system to monitor catecholaminergic projections in vivo over the timeframes that such events occur. Green fluorescent protein (GFP) expression driven by tyrosine hydroxylase promoter in a transgenic mouse line enabled us to perform two-photon imaging of cortical catecholaminergic projections through a cranial window. Repetitive imaging of the same axons over 24 h revealed the highly dynamic nature of catecholaminergic boutons. Surprisingly, administration of single high dose methamphetamine (MAP) induced a transient increase in bouton volumes. This new method opens avenues for longitudinal in vivo evaluation of structural changes at single release sites of catecholamines in association with physiology and pathology of cortical functions

Suppression of backward scattering of Dirac fermions in iron pnictides Ba(Fe1−x_{1-x}Rux_xAs)2_2

We report electronic transport of Dirac cones when Fe is replaced by Ru, which has an isoelectronic electron configuration to Fe, using single crystals of Ba(Fe$_{1-x}$Ru$_x$As)$_2$. The electronic transport of parabolic bands is shown to be suppressed by scattering due to the crystal lattice distortion and the impurity effect of Ru, while that of the Dirac cone is not significantly reduced due to the intrinsic character of Dirac cones. It is clearly shown from magnetoresistance and Hall coefficient measurements that the inverse of average mobility, proportional to cyclotron effective mass, develops as the square root of the carrier number (n) of the Dirac cones. This is the unique character of the Dirac cone linear dispersion relationship. Scattering of Ru on the Dirac cones is discussed in terms of the estimated mean free path using experimental parameters.Comment: 6 pages, 3 figures, To be published in Phys. Rev.

Kiso observations for 20 GRBs in HETE-2 era

We have established a GRB follow-up observation system at Kiso observatory (Japan) in 2001. Since the east Asian area had been blank for the GRB follow-up observational network, this observational system is very important in studying the temporal and spectral evolution of early afterglows. Using this system, we have performed quick observations for optical afterglows from early phase based on HETE-2 and INTEGRAL alerts. Thanks to the quick follow-up observation system, we have been able to use the Kiso observatory in 20 events, and conduct their follow-up observations in optical and near infrared wavelengths.Comment: 5 pages, 4 figure. Accepted for publication into "il nuovo cimento". Proceeding of the 4th Rome GRB conference, eds. L. Piro, L. Amati, S. Covino, B. Gendr

GRB 070518: A Gamma-ray Burst with Optically Dim Luminosity

We present our optical observations of {\em Swift} GRB 070518 afterglow obtained at the 0.8-m Tsinghua University-National Astronomical Observatory of China telescope (TNT) at Xinglong Observatory. Our follow-up observations were performed from 512 sec after the burst trigger. With the upper limit of redshift $\sim$0.7, GRB 070518 is found to be an optically dim burst. The spectra indices $\beta_{ox}$ of optical to X-ray are slightly larger than 0.5, which implies the burst might be a dark burst. The extinction $A_{V}$ of the host galaxy is 3.2 mag inferred from the X-ray hydrogen column density with Galactic extinction law, and 0.3 mag with SMC extinction law. Also, it is similar to three other low-redshift optically dim bursts, which belong to XRR or XRF, and mid-term duration($T_{90}<10$, except for GRB 070419A, $T_{90}$=116s). Moreover, its $R$ band afterglow flux is well fitted by a single power-law with an index of 0.87. The optical afterglow and the X-ray afterglow in the normal segment might have the same mechanism, as they are consistent with the prediction of the classical external shock model. Besides, GRB 070518 agrees with Amati relation under reasonable assumptions. The Ghirlanda relation is also tested with the burst.Comment: 8 pages, 4 figures, MNRAS accepte

The GRB 071112C: A Case Study of Different Mechanisms in X-ray and Optical Temporal Evolution

We present the study on GRB 071112C X-ray and optical light curves. In these two wavelength ranges, we have found different temporal properties. The R-band light curve showed an initial rise followed by a single power-law decay, while the X-ray light curve was described by a single power-law decay plus a flare-like feature. Our analysis shows that the observed temporal evolution cannot be described by the external shock model in which the X-ray and optical emission are produced by the same emission mechanism. No significant color changes in multi-band light curves and a reasonable value of the initial Lorentz factor ({\Gamma}0 = 275 \pm 20) in a uniform ISM support the afterglow onset scenario as the correct interpretation for the early R-band rise. The result suggests the optical flux is dominated by afterglow. Our further investigations show that the X-ray flux could be created by an additional feature related to energy injection and X-ray afterglow. Different theoretical interpretations indicate the additional feature in X-ray can be explained by either late internal dissipation or local inverse-Compton scattering in the external shock.Comment: 20 pages, 3 figures, accepted for publication in Ap