On the complexity of string folding

A fold of a finite string S over a given alphabet is an embedding of S in some fixed infinite grid, such as the square or cubic mesh. The score of a fold is the number of pairs of matching string symbols which are embedded at adjacent grid vertices. Folds of strings and sets of strings in two- and three-dimensional meshes are considered, and the corresponding problems of optimizing the score or achieving a given target score are shown to be NP-hard

Hollow fiber clinostat for simulating microgravity in cell culture

A clinostat for simulating microgravity on cell systems carried in a fiber fixedly mounted in a rotatable culture vessel is disclosed. The clinostat is rotated horizontally along its longitudinal axis to simulate microgravity or vertically as a control response. Cells are injected into the fiber and the ends of the fiber are sealed and secured to spaced end pieces of a fiber holder assembly which consists of the end pieces, a hollow fiber, a culture vessel, and a tension spring with three alignment pins. The tension spring is positioned around the culture vessel with its ends abutting the end pieces for alignment of the spring. After the fiber is secured, the spring is decompressed to maintain tension on the fiber while it is being rotated. This assures that the fiber remains aligned along the axis of rotation. The fiber assembly is placed in the culture vessel and culture medium is added. The culture vessel is then inserted into the rotatable portion of the clinostat and subjected to rotate at selected rpms. The internal diameter of the hollow fiber determines the distance the cells are from the axis of rotation

Local Government, Taxes, and Guns: Successful Policy Innovation in Three Colombian Cities

This paper evaluates transformative policy innovations with respect to security and taxation in the three main Colombian cities: Bogotá, Medellín, and Cali. In the first two, such policies were associated with huge success. Elsewhere we (Gutiérrez et al. 2009) have tagged these transformation processes as ‘urban/metropolitan miracles’. The term comes from the fact that both common citizens and pundits considered these to be extremely unlikely, that they were fast, and that they were large-scale. We argue, that the success of Bogotá and Medellín was the result of a set of institutional underpinnings basically related to the 1991 constitution; the opening of a window of opportunity for new political actors; and, as a result, the formation of a new government coalition and ‘governance formula’. Anti-particularism was a language related to political demands— linked organically with the pro-1991 constitution movement—which became effective .../urban security, state building, public policies

Trust-Building through Social Media Communications in Disaster Management

open4Social media provides a digital space – a meeting place, for different people, often representing one or more groups in a society. The use of this space during a disaster, especially where information needs are high and the availability of factually accurate and ethically sourced data is scarce, has increased substantially over the last 5-10 years. This paper attempts to address communication in social media and trust between the public and figures of authority during a natural disaster in order to suggest communication strategies that can enhance or reinforce trust between these bodies before, during and after a natural disaster.openM. G. Busà; M. T. Musacchio; S. Finan; C. FennelBusa', MARIA GRAZIA; Musacchio, MARIA TERESA; S., Finan; C., Fenne

Reforming the U. S. health care system: where there's a will, there could be a way

The essay in the 2005 annual report summarizes the themes and consensus-based prescriptions for action that emerged from the Boston Fed's 50th economic conference, Wanting It All: The Challenge of Reforming the U.S. Health Care System, held in June 2005.Health care reform ; Medical care, Cost of

Direct gaze modulates face recognition in young infants

From birth, infants prefer to look at faces that engage them in direct eye contact. In adults, direct gaze is known to modulate the processing of faces, including the recognition of individuals. In the present study, we investigate whether direction of gaze has any effect on face recognition in four-month-old infants. Four-month infants were shown faces with both direct and averted gaze, and subsequently given a preference test involving the same face and a novel one. A novelty preference during test was only found following initial exposure to a face with direct gaze. Further, face recognition was also generally enhanced for faces with both direct and with averted gaze when the infants started the task with the direct gaze condition. Together, these results indicate that the direction of the gaze modulates face recognition in early infancy

Assessing Financial Vulnerability in the Nonprofit Sector

Effective nonprofit governance relies upon understanding an organization's financial condition and vulnerabilities. However, financial vulnerability of nonprofit organizations is a relatively new area of study. In this paper, we compare two models used to forecast bankruptcy in the corporate sector (Altman 1968 and Ohlson 1980) with the model used by nonprofit researchers (Tuckman and Chang 1991). We find that the Ohlson model has higher explanatory power than either Tuckman and Chang's or Altman's in predicting four different measures of financial vulnerability. However, we show that none of the models, individually or combined, are effective in predicting financial distress. We then propose a more comprehensive model of financial vulnerability by adding two new variables to represent reliance on commercial-type activities to generate revenues and endowment sufficiency. We find that this model outperforms Ohlson's model and performs substantially better in explaining and predicting financial vulnerability. Hence, the expanded model can be used as a guide for understanding the drivers of financial vulnerability and for identifying more effective proxies for nonprofit sector financial distress for use in future research. This publication is Hauser Center Working Paper No. 27. The Hauser Center Working Paper Series was launched during the summer of 2000. The Series enables the Hauser Center to share with a broad audience important works-in-progress written by Hauser Center scholars and researchers

Nurses\u27 Own Birth Experiences Influence Labor Support Attitudes and Behaviors

Objective To describe the attitudes of intrapartum nurses about the importance of and intent to provide professional labor support (PLS); barriers to PLS, such as perceived subjective norms and perceived behavioral control; and relationships among attitudes, behaviors, and nurse and site characteristics. Design A cross-sectional, mixed-methods, descriptive design was guided by the Theory of Planned Behavior. Setting Three hospital sites in one region of a single Midwestern state. Participants Sixty intrapartum nurses participated. Methods The Labor Support Questionnaire and demographic questionnaire were administered online. The Labor Support Questionnaire is used to measure attitudes about the importance of and intended behaviors associated with labor support. Results Nurse Caring Behaviors was the highest rated PLS dimension. Participants\u27 own personal birth experiences and length of current intrapartum experience were positively correlated with attitudes about and intent to provide PLS. Barriers to PLS included staffing, documentation, physicians, use of epidural analgesia, doulas, and birth plans. Conclusion Personal birth and work experience influenced attitudes about and intent to provide PLS and demonstrated the relationships described in the Theory of Planned Behavior. Intrapartum nurses may benefit from an examination of their personal experiences to see how they might influence attitudes about PLS. Enhanced training and expanded labor and birth experience for novice nurses or students may improve attitudes and intended behavior with regard to PLS. Further investigations of the factors that affect integration of PLS into care are important to promote healthy birth outcomes