2,797 research outputs found

    Teaching International Law To Undergraduates And Other Non-Legal Audiences: Practical Suggestions For Pedagogical Approaches

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    Unquestionably, there is growing interest in the subject of international law at several educational levels and among a broad constituency of students. This is due to a variety of factors

    The International Whaling Commission: Challenges From Within And Without

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    Despite the growing number of international organizations dedicated to the conservation and management of living marine resources, very few generate the controversy of the International Whaling Commission (IWC)

    Scientific Research Whaling In International Law: Objectives And Objections

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    Scientific research whaling is one of the most hotly debated points of contention between anti-whaling forces and those few remaining states that seek to resume commercial whaling

    Moving From Single-Species Management To Ecosystem Management In Regional Fisheries Management Organizations

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    Even though reference to the modem framework of ocean governance begins with the 1982 United Nations Convention on the Law of the Sea (UNCLOS),\u27 it certainly does not end there

    U.S. Membership In Unclos: What Effects For The Marine Environment?

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    The issue of whether or not the U.S. should ratify the United Nations Convention on the Law of the Sea (UNCLOS or the Convention)\u27 has been debated since the treaty was concluded in 1982

    Bacteria Adhesion Is Mechanosensitive To Polymer Gel Properties

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    Biofilm-related infections are a class of notoriously difficult to treat healthcare-associated infections, which commonly develop on the surface of implanted medical devices. Despite lacking visual, auditory, and olfactory perception, bacteria detect and settle on surfaces, however, how the intrinsic properties of materials affect the initial adhesion microorganisms remains relatively unknown. By unveiling the structure-property relationships between polymer materials and microbial adhesion, we could guide the design of materials a priori to resist the adhesion of infection causing microorganisms, such as Staphylococcus aureus. In this presentation, I will discuss the effect that fundamental properties of polymer coatings (i.e., molecular architecture, stiffness, and thickness) have on the surface-associated transport of bacteria and on the adhesion of bacteria under quiescent conditions. By decoupling the effects of molecular architecture, stiffness, and thickness from coating chemistry, we have unlocked specific structure-property relationships that can be tailored to control the degree of bacterial adhesion and subsequently, reduce the formation of biofilms. This work provides insight into the future design of bacteria-resistant surfaces with broad implications for applications including medical implants and equipment

    Sensory Aids Research

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    Contains reports on three research projects.National Institutes of Health (Grant MH-04737-02)National Science Foundation (Grant G-16526)United States Air Force, Electronic Systems Division (Contract AF19(628)-258

    Copy Number Alterations and Methylation in Ewing's Sarcoma

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    Ewing's sarcoma is the second most common bone malignancy affecting children and young adults. The prognosis is especially poor in metastatic or relapsed disease. The cell of origin remains elusive, but the EWS-FLI1 fusion oncoprotein is present in the majority of cases. The understanding of the molecular basis of Ewing's sarcoma continues to progress slowly. EWS-FLI1 affects gene expression, but other factors must also be at work such as mutations, gene copy number alterations, and promoter methylation. This paper explores in depth two molecular aspects of Ewing's sarcoma: copy number alterations (CNAs) and methylation. While CNAs consistently have been reported in Ewing's sarcoma, their clinical significance has been variable, most likely due to small sample size and tumor heterogeneity. Methylation is thought to be important in oncogenesis and balanced karyotype cancers such as Ewing's, yet it has received only minimal attention in prior studies. Future CNA and methylation studies will help to understand the molecular basis of this disease

    Remote sensing applications to hydrologic modeling

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    An energy balance snowmelt model for rugged terrain was devised and coupled to a flow model. A literature review of remote sensing applications to hydrologic modeling was included along with a software development outline
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