INVESTIGATION OF PHYTOCHEMICAL, MINERAL CONTENT AND PHYSIOCHEMICAL PROPERTY OF A POLYHERBAL EXTRACT

Objective: The objective of the present study was to investigate the phytochemical, mineral content, and physiochemical properties of a polyherbalextract (PE).Methods: Fresh plants Punica granatum (rind), Catharanthus roseus, Gymnema sylvestre, Cissus quadrangularis, Garcinia cambogia, Tinosporacordifolia, Terminalia Arjuna, Urginea indica, Ficus racemosa were selected for the PE. The plants were collected from various areas in and aroundCoimbatore district. The plants were washed, air dried, and coarsely powdered. 10 g of each plant powder has undergone various extract analysis forits phytochemical screening. The coarse extract called PE is been tested for physiochemical properties and its mineral content.Results: The presence of secondary metabolites such as flavonoids, glycosides, phenolic compounds, and tannins in all the extract but highest in thehydroethanolic extract. The physiochemical properties showed the appropriate pH and solubility of PE.Conclusion: Our findings provide that PE contain medicinally important secondary metabolites for the treatment of various diseases like cancer,cardiovascular diseases, and diabetes mellitus in the traditional folk medicine.Keywords: Punica granatum (rind), Catharanthus roseus, Gymnema sylvestre, Cissus quadrangularis, Garcinia cambogia, Tinospora cordifolia,Terminalia Arjuna, Urginea indica, Ficus racemosa, Cardiovascular diseases, Polyherbal extract

BANGALORE UNIVERSITY ACADEMIC LIBRARY NETWORK (BALNET)

Bangalore University has three constituent colleges and 440 Affiliated Colleges. The University has a Central Library at a sprawling campus called Jnana Bharati and a Branch library in the heart of the city at the Central College campus. All the 440 affiliated colleges have independent libraries. A number of these libraries have already computerized their housekeeping operations and have created bibliographical databases of their collections.BALNET will develop a resource sharing model by which all participating libraries can avail inter-library loan and document delivery services. In the proposed model the online union catalogue will students and faculty at the BU and any of the colleges to search for required monographs, serials, conference proceedings, articles. The authors has given an overview of proposed network model

Resuscitation preparedness for general practice

General practices are not exempted from situations dealing with dire emergencies. For general practitioners to be effective in coping with such situations, they should at all times be prepared to resuscitate patients. This article gives an overview of the preparation required to manage such events. (SA Fam Pract 2003;45(1):9-13) Keywords: Resuscitation, emergency medicine, preparednes

4-{[5-(4-Chloro­phen­yl)-1-(4-fluoro­phen­yl)-1H-pyrazol-3-yl]carbon­yl}-N-ethyl­piperazine-1-carboxamide

The asymmetric unit of the title compound, C23H23ClFN5O2, contains two crystallographically independent mol­ecules. In one mol­ecule, the pyrazole ring makes dihedral angles of 43.93 (7) and 35.82 (7)°, respectively, with the fluoro- and chloro-substituted benzene rings, while the corresponding angles in the other mol­ecule are 52.26 (8) and 36.85 (7)°. The piperazine rings adopt chair conformations. In the crystal, adjacent mol­ecules are connected via inter­molecular N—H⋯O, C—H⋯F, C—H⋯N and C—H⋯O hydrogen bonds, forming a two-dimensional network parallel to the bc plane. The crystal structure is further stabilized by a weak π–π inter­action with a centroid–centroid distance of 3.6610 (8) Å and by C—H⋯π inter­actions

Frand and Compulsory Licenses: Analysis and Comparison

This section compares two different forms of licenses being FRAND and complusory license. Both forms of licenses are critical to achieve access to otherwise difficult to access technologies. The FRAND licenses have been widely embraced, especially in the software, mobile phones, and communications sectors. Compulsory licenses have been sparingly used by Governments where the public\u27s need for the invention was considered to over-weigh the needs of the patentee, essentially for pharmaceuticals. Compulsory licenses have been universally criticized for being an imposed burden on the patentee. In comparing these two forms of licenses, this section outlines that despite the obvious differences operationally both of these have stark similarities and highlights areas where complusory licenses operate more efficiently. In doing so, this section highlights that perhaps each of the forms of licenses can borrow from the other to minimize the weaknesses to ulitmately enable more access for critical inventions

Frand and Compulsory Licenses: Analysis and Comparison

This section compares two different forms of licenses being FRAND and complusory license. Both forms of licenses are critical to achieve access to otherwise difficult to access technologies. The FRAND licenses have been widely embraced, especially in the software, mobile phones, and communications sectors. Compulsory licenses have been sparingly used by Governments where the public\u27s need for the invention was considered to over-weigh the needs of the patentee, essentially for pharmaceuticals. Compulsory licenses have been universally criticized for being an imposed burden on the patentee. In comparing these two forms of licenses, this section outlines that despite the obvious differences operationally both of these have stark similarities and highlights areas where complusory licenses operate more efficiently. In doing so, this section highlights that perhaps each of the forms of licenses can borrow from the other to minimize the weaknesses to ulitmately enable more access for critical inventions

tert-Butyl 4-{[5-(4-chloro­phen­yl)-1-(4-fluoro­phen­yl)-1H-pyrazol-3-yl]carbon­yl}piperazine-1-carboxyl­ate

In the title pyrazole derivative, C25H26ClFN4O3, both benzene rings are twisted out of the plane through the pyrazole ring, with dihedral angles of 67.62 (10) and 27.63 (10)° for the fluoro- and chloro-substituted rings, respectively. The dihedral angle between the two benzene rings is 64.54 (9)°. The piperazine ring (with a chair conformation) is linked to the pyrazole ring via a carbonyl spacer and is orientated to lie to one side of the pyrazole plane. In addition to an intra­molecular C—H⋯N contact, there are inter­molecular C—H⋯O inter­actions, which generate a supra­molecular chain with an undulating topology along the c axis that is sustained by alternating centrosymmetric ten-membered {⋯HCNCO}2 and {⋯HC3O}2 synthons