Anti-plasmodia activity of leaf extracts of Calotropis procera Linn

The leaves of Calotropis procera were air dried, grounded and soaked with ethanol. The extracts obtained (29.79g, CP1) was fractionated sequentially using aqueous methanol with petroleum ether, chloroform and ethyl acetate respectively. The residue of ethanol extract (marc) was extracted with 5M HCl, basified and extracted with chloroform. These were labeled as CP1-01 to CP1-05 for the plant. Each of these fractions was phytochemically screened to detect the class of secondary metabolite present. The fractions obtained from the plant were found to be selectively active against brine shrimp larvae. These fractions were also subjected to antimalaria parasites bioassay. Fractions CP1, CP1-04 and CP1-05 were found to be active against tested organisms, withCP1-04 being the most active. CP1-04 was further subjected to activity guided column chromatography that led to the isolation of two pure compounds CP1-04-1 and CP1-04-61. Compound CP1-04-61 was found to be active against the malaria parasite. This was further purified and subjected to qualitative and quantitative analysis

Phytochemical Screening and Antimicrobial Activities of Terminalia catappa , Leaf Extracts

The powdered leaf of Terminalia catappa was extracted using ethanol and partitioned into n-hexane, chloroform, ethyl acetate and aqueous methanol fractions. Test for the presence of secondary metabolites showed the presence of alkaloids, reducing sugars, saponins, tannins, resins and steroids in ethanol soluble fraction. The antimicrobial assay of n-hexane, chloroform and ethyl acetate fractions indicated a positive activity against the bacterial isolates tested. Chloroform fraction showed activity against Gram-negative Escherichia coli and Salmonella typhi at 500\ub5g/disc, while ethanol and aqueous methanol fractions were active only on Salmonella typhi at concentrations of 300 - 500\ub5g/disc. The present study revealed that the plant extracts contain phytochemicals responsible for the activity against Salmonella typhi

Spectral Signatures of the Diffusional Anomaly in Water

Analysis of power spectrum profiles for various tagged particle quantities in bulk SPC/E water is used to demonstrate that variations in mobility associated with the diffusional anomaly are mirrored in the exponent of the \onebyf\ region. Monitoring of \onebyf behaviour is shown to be a simple and direct method for linking phenomena on three distinctive length and time scales: the local molecular environment, hydrogen bond network reorganisations and the diffusivity. The results indicate that experimental studies of supercooled water to probe the density dependence of $1/f^\alpha$ spectral features, or equivalent stretched exponential behaviour in time-correlation functions, will be of interest.Comment: 5 Pages, 4 Figure

Invigorasi Benih Padi Gogo Lokal untuk Meningkatkan Vigor dan Mengatasi Permasalahan Dormansi Fisiologis Pascapanen

The objective of this research was to evaluate the effect of seed invigoration on improving seed viability and vigor, and to overcome problems of postharvest physiological dormancy of upland rice seed. The research was conducted from February to June 2011 at Agrotechnology Laboratory, Faculty of Agriculture, Halu Oleo University. The experiment used randomized complete design which consisted of 13 treatments, i.e control (G0), Hidration-Dehidration (G1), Matriconditioning using ground brick (G2), Matriconditioning using ground burned-rice husk (G3), Bacillus CKD061 (G4), P. fluorescens PG01 (G5), Serratia CMN175 (G6), Biomatriconditioning using ground brick + Bacillus CKD061 (G7), Biomatriconditioning using ground brick + P. fluorescens PG01 (G8), Biomatriconditioning using ground brick + Serratia CMN175 (G9), Biomatriconditioning using ground burned-rice husk + Bacillus CKD061 (G10), Biomatriconditioning using ground burned-rice husk + P. fluorescens PG01 (G11), Biomatriconditioning using ground burned-rice husk + Serratia CMN175 (G12). Each treatment was replicated three times, therefore, overall there were 36 experimental units. Data obtained were analyzed using analysis of variance and followed with Duncan's Multiple Range Test. The research results showed that bio-invigoration treatments integrated with rhizobacteria were effective to overcome the problems of postharvest physiological dormancy when local upland rice seeds were harvested. In addition, this treatment was also able to increase viability and vigour of the seed. Among treatments tested, the use of Bacillus sp. CKD061 or P. fluorescens PG01, either independently or integrated with matriconditioning using ground brick or ground burned- rice husk was more effective in improving viability and vigour of local upland rice seed compared to other treatments

"Smoking gun" signatures of topological milestones in trivial materials by measurement fine-tuning and data postselection

Exploring the topology of electronic bands is a way to realize new states of matter with possible implications for information technology. Because bands cannot always be observed directly, a central question is how to tell that a topological regime has been achieved. Experiments are often guided by a prediction of a unique signal or a pattern, called "the smoking gun". Examples include peaks in conductivity, microwave resonances, and shifts in interference fringes. However, many condensed matter experiments are performed on relatively small, micron or nanometer-scale, specimens. These structures are in the so-called mesoscopic regime, between atomic and macroscopic physics, where phenomenology is particularly rich. In this paper, we demonstrate that the trivial effects of quantum confinement, quantum interference and charge dynamics in nanostructures can reproduce accepted smoking gun signatures of triplet supercurrents, Majorana modes, topological Josephson junctions and fractionalized particles. The examples we use correspond to milestones of topological quantum computing: qubit spectroscopy, fusion and braiding. None of the samples we use are in the topological regime. The smoking gun patterns are achieved by fine-tuning during data acquisition and by subsequent data selection to pick non-representative examples out of a fluid multitude of similar patterns that do not generally fit the "smoking gun" designation. Building on this insight, we discuss ways that experimentalists can rigorously delineate between topological and non-topological effects, and the effects of fine-tuning by deeper analysis of larger volumes of data.Comment: Data are available through Zenodo at DOI: 10.5281/zenodo.834930

Planar Josephson Junctions Templated by Nanowire Shadowing

More and more materials, with a growing variety of properties, are built into electronic devices. This is motivated both by increased device performance and by the studies of materials themselves. An important type of device is a Josephson junction based on the proximity effect between a quantum material and a superconductor, useful for fundamental research as well as for quantum and other technologies. When both junction contacts are placed on the same surface, such as a two-dimensional material, the junction is called ``planar". One outstanding challenge is that not all materials are amenable to the standard planar junction fabrication. The device quality, rather than the intrinsic characteristics, may be defining the results. Here, we introduce a technique in which nanowires are placed on the surface and act as a shadow mask for the superconductor. The advantages are that the smallest dimension is determined by the nanowire diameter and does not require lithography, and that the junction is not exposed to chemicals such as etchants. We demonstrate this method with an InAs quantum well, using two superconductors - Al and Sn, and two semiconductor nanowires - InAs and InSb. The junctions exhibit critical current levels consistent with transparent interfaces and uniform width. We show that the template nanowire can be operated as a self-aligned electrostatic gate. Beyond single junctions, we create SQUIDs with two gate-tunable junctions. We suggest that our method can be used for a large variety of quantum materials including van der Waals layers, topological insulators, Weyl semimetals and future materials for which proximity effect devices is a promising research avenue.Comment: Written using The Block Method. Data on Zenodo DOI: https://doi.org/10.5281/zenodo.641608