Mixing in the D0 system - Results from collider experiments

Mixing in the D0 system may provide a sensitive probe for new physics beyond the Standard Model (SM) but has so far eluded experimental observation. The SM predictions are typically small (< 10^{-3}) for the mixing parameters x, y which, in the absence of charge-parity (CP) symmetry violation, measure the mass (x= Delta(m)/Gamma) and lifetime (y= Delta(Gamma)/2Gamma) difference of the CP eigenstates in the D0 system. The asymmetric B-factory experiments BABAR and Belle open up the opportunity of measuring x, y with unprecedented statistical precision and sample purities. Results from BABAR and Belle, and from CLEO are reviewed.Comment: 28 pages, 7 figures, typos correcte

Transition from radiatively inefficient to cooling dominated phase in two temperature accretion discs around black holes

We investigate the transition of a radiatively inefficient phase of a viscous two temperature accreting flow to a cooling dominated phase and vice versa around black holes. Based on a global sub-Keplerian accretion disc model in steady state, including explicit cooling processes self-consistently, we show that general advective accretion flow passes through various phases during its infall towards a black hole. Bremsstrahlung, synchrotron and inverse Comptonization of soft photons are considered as possible cooling mechanisms. Hence the flow governs a much lower electron temperature ~10^8 - 10^{9.5}K compared to the hot protons of temperature ~10^{10.2} - 10^{11.8}K in the range of the accretion rate in Eddington units 0.01 - 100. Therefore, the solutions may potentially explain the hard X-rays and the gamma-rays emitted from AGNs and X-ray binaries. We finally compare the solutions for two different regimes of viscosity and conclude that a weakly viscous flow is expected to be cooling dominated compared to its highly viscous counterpart which is radiatively inefficient. The flow is successfully able to reproduce the observed luminosities of the under-fed AGNs and quasars (e.g. Sgr A*), ultra-luminous X-ray sources (e.g. SS433), as well as the highly luminous AGNs and ultra-luminous quasars (e.g. PKS 0743-67) at different combinations of the mass accretion rate and ratio of specific heats.Comment: 13 pages including 8 figures; couple of typos corrected; to appear in Research in Astronomy and Astrophysic

Morphine Metabolism in Human Skin Microsomes

For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin. However, for topical administration it is important to know whether the substance is biotransformed in the skin as this can eventually reduce the concentration of the active agent considerably. We use skin microsomes to elucidate the impact of skin metabolism on the activity of topically applied morphine. We are able to demonstrate that morphine is only glucuronidated in traces, indicating that the biotransformation in the skin can be neglected when morphine is applied topically. Hence, there is no need to take biotransformation into account when setting up the treatment regimen. Copyright (C) 2012 S. Karger AG, Base

Methods for the Study of Transverse Momentum Differential Correlations

We introduce and compare three differential correlation functions for the study of transverse momentum correlation in $p+p$ and $A+A$ collisions. These consist of {\it inclusive}, {\it event-wise} and a differential version of the correlation measure $\tilde C$ introduced by Gavin \cite{Gavin} for experimental study of the viscosity per unit entropy of the matter produced in $A+A$ collisions. We study the quantitative difference between the three observables on the basis of PYTHIA simulations of $p+p$ collisions and $A+A$ collisions consisting of an arbitrary superposition of $p+p$ collision events at $\sqrt{s} =$200 GeV. We observe that {\it inclusive} and {\it event-wise} correlation functions are remarkably identical to each other where as the observable $\tilde C$ differs from the two. We study the robustness and efficiency dependencies of these observables based on truncated Taylor expansions in efficiency in $p+p$ collisions and on the basis of Monte Carlo simulation using an adhoc detector efficiency parameterization. We find that all the three observables are essentially independent of detector efficiency. We additionally study the scaling of the correlation measures and find all the observables exhibit an approximate $1/N$ dependence of the number of participants ({\it N}) in $A+A$ collisions. Finally, we study the impact of flow-like anisotropy on the {\it inclusive} correlation function and find flow imparts azimuthal modulations similar to those observed with two-particle densities.Comment: 19 pages, 8 figure

Investigating texture six zero lepton mass matrices

Texture six zero Fritzsch like as well as non Fritzsch like hermitian lepton mass matrices (144 combinations in all) have been investigated for both Majorana and Dirac neutrinos for their compatibility with the current neutrino oscillation data, keeping in mind the hierarchy of neutrino masses. All the combinations considered here for Majorana neutrino masses are ruled out by the existing data in the case of inverted hierarchy and degenerate scenario. For Majorana neutrinos with normal hierarchy, only 16 combinations can accommodate the experimental data. Assuming neutrinos to be Dirac particles, normal hierarchy, inverted hierarchy as well as degenerate neutrinos are ruled out for all combinations of texture 6 zero hermitian mass matrices.Comment: 14 pages, 2 figure