Automated RFID based library management systems

RFID provides one of the best solutions for the identification of assets. RFID is a new generation which provides auto identification and data collection technique. RFID allows identification of tagged books, using radio frequency. RFID based Library Management System (LMS) will help us to increase the flow of transaction for a library. The proposed system of LMS is based on UHF RFID readers, along with the antennas at library entrance and on all other transactional points of the library. This work discusses elimination of transactional module from existing RFID based Library Management Syste

Ventricular Assist Device-Related Haemolysis Presenting with Acute Pancreatitis

Acute pancreatitis is one of the rare complications in patients fitted with a left ventricular assist device (LVAD). We herein report a case of acute pancreatitis in a patient with LVAD triggered by intravascular haemolysis. A 44-year-old man with non-ischaemic cardiomyopathy (NICM) after VAD implantation presented with epigastric pain. Laboratory work-up showed acute pancreatitis and haemolysis. As there was concern that device thrombosis was causing haemolysis, the patient was started on unfractionated heparin infusion. The patient was discharged when haemolysis and pancreatitis had resolved. To our knowledge, VAD-associated haemolysis presenting with acute pancreatitis is infrequently described in the literature

Is your extra X chromosome holding you back? An insight into female education and academic careers in STEMM

This review discusses whether gender inequality still exists within medical, scientific and engineering academia, with regards to the career development of academic staff. In the 1970s it was suggested that women who are talented and educated with family responsibilities tend to come across problems of self-confidence and identity when attempting to enhance their professional careers, and although many are successful in doing so, others find it more challenging. By the 1990s, it was indicated that the main gender inequality mechanism in academia is the commonly known fact that women’s career development in the academic hierarchy is slower than that of men. In the past 50 years, laws and attitudes of many societies, industries and countries, have changed to promote gender equality. What is the impact of these changes, does inequality still exist and what mechanisms exist to address these issues? This review looks in depth at the links between gender equality and continuing personal and professional development (CPPD), in which individuals at work are educated more about the workplace environment and their job roles and performance. The different types, requirements and success rates of CPPD within the scientific (especially medical) academic community is discussed with an emphasis on gender equality

Space Charge–Limited Current Model for Polymers

Polymers have exceptional charge transport mechanism as a combination of delocalization and localization of charge carriers with intramolecular and intermolecular charge interaction, respectively, and most of the time, it is interpreted with Mott-Gurney space charge–limited current model. As polymers are full of traps, therefore, Mott-Gurney space charge–limited model is modified with various trap distributions as trapped space charge–limited model. The most crucial parameter affected by the nature and distribution of traps is the carrier mobility, and it is argued that space charge–limited model is an acceptable choice for the mobility measurement for polymer. Similarly, in order to account the commonly observed lowering of trap barrier height at higher electric field, the Mott-Gurney space charge–limited current is further modified with little variations, which are evaluated and discussed in detail

Process Optimization and Design of an Automation Controller for a Multidisciplinary Combat Engineering System

Design of an automation controller for a “Electro-Hydro-Mechanical Object Laying System” is presented in this paper, which is a multidisciplinary equipment consisting of Electromechanical and Hydraulic Actuators and large number of sensors for process feedback. There are complex mechanisms and processes involved in this system, which are required to be operated/executed in sequential and parallel manner in real time. The operation of spatially distributed Electromechanical & Hydraulic actuators with feedbacks from multiple type of sensors are required to be synchronized for multiple activities at a faster rate along with safely handling of the objects. All the activities are automated with minimum human intervention to avoid risk to the crew. This paper mainly focuses on electronic controller hardware design for military environment and process optimization to achieve faster object laying rate

Hemoglobin E syndromes in Pakistani population

<p>Abstract</p> <p>Background</p> <p>Hemoglobin E is an important hemoglobin variant with a worldwide distribution. A number of hemoglobinopathies have been reported from Pakistan. However a comprehensive description of hemoglobin E syndromes for the country was never made. This study aimed to describe various hemoglobin E disorders based on hematological parameters and chromatography. The sub-aim was to characterize hemoglobin E at molecular level.</p> <p>Methods</p> <p>This was a hospital based study conducted prospectively for a period of one year extending from January 1 to December 31, 2008. EDTA blood samples were analyzed for completed blood counts and hemoglobin variants through automated hematology analyzer and Bio-Rad beta thalassaemia short program respectively. Six samples were randomly selected to characterize HbE at molecular level through RFLP-PCR utilizing <it>Mnl</it>I restriction enzyme.</p> <p>Results</p> <p>During the study period, 11403 chromatograms were analyzed and Hb E was detected in 41 (or 0.36%) samples. Different hemoglobin E syndromes identified were HbEA (n = 20 or 49%), HbE/β-thalassemia (n = 14 or 34%), HbEE (n = 6 or 15%) and HbE/HbS (n = 1 or 2%). Compound heterozygosity for HbE and beta thalassaemia was found to be the most severely affected phenotype. RFLP-PCR utilizing <it>Mnl</it>I successfully characterized HbE at molecular level in six randomly selected samples.</p> <p>Conclusions</p> <p>Various HbE phenotypes are prevalent in Pakistan with HbEA and HbE/β thalassaemia representing the most common syndromes. Chromatography cannot only successfully identify hemoglobin E but also assist in further characterization into its phenotype including compound heterozygosity. Definitive diagnosis of HbE can easily be achieved through RFLP-PCR.</p

Role of special coagulation studies for preoperative screening of thrombotic complications in simultaneous pancreas-kidney transplantation

Background: Vascular thrombosis is a well-known complication after simultaneous pancreas-kidney (SPK) transplantation procedures. The role of preoperative special coagulation studies to screen patients at high risk for vascular thrombosis is unclear and not well studied

Cost-effective Paper-based Diagnostic Using Split Proteins to Detect Yeast Infections

The common yeast infection, vulvovaginal candidiasis, affects three out of four women throughout their lifetime and can be spread to their child in the form of oral candidiasis (thrush). This disease is caused by the fungal pathogen Candida albicans, which is also a major cause of systemic candidiasis, a rarer but deadly disease with up to a 49% lethality rate. Current widely-used diagnostic methods include cell cultures, pH tests, and antibody detection, to assist effective treatment. Despite availability of various diagnostic methods, there is no inexpensive, rapid, and accurate way to detect C. albicans infection. This project aims to develop a paper-based diagnostic test for C. albicans that is, cost-effective, quick, and precise. The test detects the specific biomarkers farnesol and tyrosol produced by C. albicans by binding them to the split proteins pqsR and tyrosinase, respectively. Upon binding, a split horseradish peroxidase catalyzes and produces an amplified colorimetric signal by oxidizing the substrate tetramethylbenzidine (TMB) turning the paper blue. This test will produce a colorimetric output for a simple-to-understand diagnosis without any infrastructure. We predict that this device can give a response in under 2 minutes while costing around an estimated 10 cents per device This test may provide a way for an easy and cheap way to diagnose candidiasis worldwide, reducing the abuse of antifungals and provide an accurate way to treat vulvovaginal candidiasis and systemic candidiasis

Cost-effective Paper-based Diagnostic Using Split Proteins to Detect Yeast Infections

The common yeast infection, vulvovaginal candidiasis, affects three out of four women throughout their lifetime and can be spread to their child in the form of oral candidiasis (thrush). This disease is caused by the fungal pathogen Candida albicans, which is also a major cause of systemic candidiasis, a rarer but deadly disease with up to a 49% lethality rate. Current widely-used diagnostic methods include cell cultures, pH tests, and antibody detection, to assist effective treatment. Despite availability of various diagnostic methods, there is no inexpensive, rapid, and accurate way to detect C. albicans infection. This project aims to develop a paper-based diagnostic test for C. albicans that is, cost-effective, quick, and precise. The test detects the specific biomarkers farnesol and tyrosol produced by C. albicans by binding them to the split proteins pqsR and tyrosinase, respectively. Upon binding, a split horseradish peroxidase catalyzes and produces an amplified colorimetric signal by oxidizing the substrate tetramethylbenzidine (TMB) turning the paper blue. This test will produce a colorimetric output for a simple-to-understand diagnosis without any infrastructure. We predict that this device can give a response in under 2 minutes while costing around an estimated 10 cents per device This test may provide a way for an easy and cheap way to diagnose candidiasis worldwide, reducing the abuse of antifungals and provide an accurate way to treat vulvovaginal candidiasis and systemic candidiasis

Severe de novo Ulcerative Colitis following Ixekizumab Therapy

Ixekizumab is a selective monoclonal antibody targeting interleukin-17A, approved for the treatment of chronic plaque psoriasis. It has rarely been associated with inflammatory bowel disease (IBD) in randomized trials only. We report a unique case of severe new-onset ulcerative colitis in a young male complicated by cytomegalovirus infection who was on ixekizumab therapy for plaque psoriasis. We recommend that clinicians should exercise caution before prescribing ixekizumab as it seems to induce and exacerbate IBD