Universal Thermal Radiation Drag on Neutral Objects

We compute the force on a small neutral polarizable object moving at velocity $\vec v$ relative to a photon gas equilibrated at a temperature $T$ We find a drag force linear in $\vec v$. Its physical basis is identical to that in recent formulations of the dissipative component of the Casimir force. We estimate the strength of this universal Casimir drag force for different dielectric response functions and comment on its relevance in various contexts.Comment: 7 pages, 2 figure

Intense high-order harmonic generation in giant fullerene molecule C240_{240}

In this work the extreme nonlinear optical response of a giant fullerene molecule C$_{240}$ in strong laser field is studied. The investigation of high-order harmonic generation in such quantum nanostructure is presented modeling the C$_{240}$ molecule and its interaction with the laser field in the scope of the tight-binding mean-field approach. Electron-electron interaction is modeled by the parametrized Ohno potentail, which takes into account long-range Coulomb interaction. The essential role of many body Coulomb interaction in determining of harmonics intensities is demonstrated. We also consider vacancy-deffected molecule C$_{240}$. The presence of a single vacancy breaks the icosahedral symmetry leading to the emergence of intense even-order harmonics. We examine the dependence of moderate harmonics on laser frequency that shows the multiphoton resonant nature of high harmonics generation. The dependence of cutoff harmonics on both laser intensity and frequency are examined too.Comment: 9 pages, 10 figure

Disorder-induced effects in high-harmonic generation process in fullerene molecules

This work aims to exploit the extreme nonlinear optical response of inversion symmetric fullerene molecules subjected to various types of disorders to reveal Anderson localization effects on high harmonic generation spectra. We show that the disorder-induced effects are imprinted onto molecules' high-harmonic spectrum. Specifically, we observe a presence of strong even-order harmonic signals already for relatively small disorders. The odd-order harmonics intrinsic for disorder-free systems are generally robust to minor disorders. Both diagonal and off-diagonal disorders lift the degeneracy of states, opening up new channels for interband transitions, leading to the enhancement of the high-harmonic emission. For the second harmonic signal we obtain a law describing the dependence on the diagonal disorder strength, enabling the usage of the harmonic spectrum as a tool in measuring the disorder type and the strength.Comment: 8 pages, 9 figure

Місцева державна адміністрація як строна в адміністративних справах щодо оскарження нормативно-правових актів місцевих органів виконавчої влади

Мкртчан, Р.С. Місцева державна адміністрація як строна в адміністративних справах щодо оскарження нормативно-правових актів місцевих органів виконавчої влади / Р.С. Мкртчан // Право і безпека. - 2009. - № 1. - С. 166-170.У статті на основі аналізу нормативних джерел та думок вчених–адміністративістів розкрито питання участі місцевої державної адміністрації в адміністративному судочинстві щодо оскарження нормативно-правових актів місцевих органів виконавчої влади та на цій основі запропоноване авторське бачення вирішення проблем для покращення цього процесу. В статье на основе анализа нормативных документов и точек зрения учених– административистов раскрыт вопрос участия местной государственной администрации в административных делах по обжалованию нормативно-правовых актов местных органов исполнительной власти и на этом основании предложено авторское виденье решения проблем для улучшения этого процесса. In the article, some peculiarities of the proceedings of the cases about appealing of the normative-legal acts of local state administrative as part of administrative judiciary are mentioned on the basis of analysis of normative documents and opinions and on the basis of the thoughts of the scientists in administrative law. Possible ways of decision of the problems that arise during the given proceedings are proposed

Unfolded protein response is involved in the pathology of human congenital hypothyroid goiter and rat non-goitrous congenital hypothyroidism

Copyright: Copyright 2008 Elsevier B.V., All rights reserved.The unfolded protein response (UPR) is an intracellular signaling pathway that regulates the protein folding and processing capacity of the endoplasmic reticulum (ER). The UPR is induced by the pharmacological agents that perturb ER functions but is also activated upon excessive accumulation of the mutant secretory proteins that are unable to attain correct three-dimensional structure and are thus retained in the ER. Such defects in intracellular protein transport underlie the development of a number of phenotypically diverse inherited pathologies, termed endoplasmic reticulum storage diseases (ERSD). We have studied UPR development in two similar ERSDs, human congenital goiter caused by the C1264R and C1996S mutations in the thyroglobulin (Tg) gene and non-goitrous congenital hypothyroidism in rdw dwarf rats determined by the G2320R Tg mutation. In both cases, these mutations rendered Tg incapable of leaving the ER. A major ER chaperone immunoglobulin-binding protein (BiP), and a novel putative escort chaperone endoplasmic reticulum protein 29 KDa (ERp29) were found to be associated with Tg, which might be interpreted as the contribution of the quality control machinery to the previously shown retention of Tg in the ER. We have extended our earlier observations of ER chaperone induction with the identification of the additional ER (ERp29, ERp72, calreticulin, protein disulfide isomerase (PDI)), cytoplasmic (heat shock protein (HSP)70, HSP90) and mitochondrial (mtHSP70) upregulated chaperones and folding enzymes. Activation of the transcriptional arm of UPR, as judged by the appearance of the spliced (active) form of X-box binding protein (XBP1) and processed activating transcription factor 6 (ATF6) transcription factors was suggested to contribute to the overexpression of the ER chaperones. The processing of ATF6 was observed in both human and rat tissues with Tg mutations. Whereas, in human tissues, weak splicing of XBP1 mRNA was detected only in the C1264R mutant, all rat thyroids including wild-type contained significant amounts of the spliced form of XBP1 as opposed to human liver and rat brain tissues, implying the existence of a previously unknown tissue-specific regulation of XBP1 processing.publishersversionPeer reviewe

The impact of induced anxiety on affective response inhibition

Studying the effects of experimentally induced anxiety in healthy volunteers may increase our understanding of the mechanisms underpinning anxiety disorders. Experimentally induced stress (via threat of unpredictable shock) improves accuracy at withholding a response on the sustained attention to response task (SART), and in separate studies improves accuracy to classify fearful faces, creating an affective bias. Integrating these findings, participants at two public science engagement events (n = 46, n = 55) were recruited to explore the effects of experimentally induced stress on an affective version of the SART. We hypothesized that we would see an improved accuracy at withholding a response to affectively congruent stimuli (i.e. increased accuracy at withholding a response to fearful 'no-go' distractors) under threat of shock. Induced anxiety slowed reaction time, and at the second event quicker responses were made to fearful stimuli. However, we did not observe improved inhibition overall during induced anxiety, and there was no evidence to suggest an interaction between induced anxiety and stimulus valence on response accuracy. Indeed Bayesian analysis provided decisive evidence against this hypothesis. We suggest that the presence of emotional stimuli might make the safe condition more anxiogenic, reducing the differential between conditions and knocking out any threat-potentiated improvement

Artificial Rydberg Atom

We analyze bound states of an electron in the field of a positively charged nanoshell. We find that the binding and excitation energies of the system decrease when the radius of the nanoshell increases. We also show that the ground and the first excited states of this system have remarkably the same properties of the highly excited Rydberg states of a hydrogen-like atom i.e. a high sensitivity to the external perturbations and long radiative lifetimes.Comment: 16 page

Minimal Model Holography for SO(2N)

A duality between the large N 't Hooft limit of the WD_N minimal model CFTs and a higher spin gravity theory on AdS3 is proposed. The gravity theory has massless spin fields of all even spins s=2,4,6,..., as well as two real scalar fields whose mass is determined by the 't Hooft parameter of the CFT. We show that, to leading order in the large N limit, the 1-loop partition function of the higher spin theory matches precisely with the CFT partition function.Comment: 21 pages, LaTe