531 research outputs found

    Incommensurate antiferromagnetic fluctuations in the two-dimensional Hubbard model

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    Commensurate and incommensurate antiferromagnetic fluctuations in the two-dimensional repulsive t-t'-Hubbard model are investigated using functional renormalization group equations. For a sufficient deviation from half filling we establish the existence of local incommensurate order below a pseudocritical temperature T_{pc}. Fluctuations not accounted for in the mean field approximation are important--they lower T_{pc} by a factor \approx2.5.Comment: 7 pages, 8 figures, some changes due to referees' comments, equivalent to published versio

    Process Mining for Dynamic Modeling of Smart Manufacturing Systems: Data Requirements

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    Modern manufacturing systems can benefit from the use of digital tools to support both short- and long-term decisions. Meanwhile, such systems reached a high level of complexity and are frequently subject to modifications that can quickly make the digital tools obsolete. In this context, the ability to dynamically generate models of production systems is essential to guarantee their exploitation on the shop-floors as decision-support systems. The literature offers approaches for generating digital models based on real-time data streams. These models can represent a system more precisely at any point in time, as they are continuously updated based on the data. However, most approaches consider only isolated aspects of systems (e.g., reliability models) and focus on a specific modeling purpose (e.g., material flow identification). The research challenge is therefore to develop a novel framework that systematically enables the combination of models extracted through different process mining algorithms. To tackle this challenge, it is critical to define the requirements that enable the emergence of automated modeling and simulation tasks. In this paper, we therefore derive and define data requirements for the models that need to be extracted. We include aspects such as the structure of the manufacturing system and the behavior of its machines. The paper aims at guiding practitioners in designing coherent data structures to enable the coupling of model generation techniques within the digital support system of manufacturing companies

    A systematic investigation of human DNA preservation in medieval skeletons

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    Ancient DNA (aDNA) analyses necessitate the destructive sampling of archaeological material. Currently, the cochlea, part of the osseous inner ear located inside the petrous pyramid, is the most sought after skeletal element for molecular analyses of ancient humans as it has been shown to yield high amounts of endogenous DNA. However, destructive sampling of the petrous pyramid may not always be possible, particularly in cases where preservation of skeletal morphology is of top priority. To investigate alternatives, we present a survey of human aDNA preservation for each of ten skeletal elements in a skeletal collection from Medieval Germany. Through comparison of human DNA content and quality we confirm best performance of the petrous pyramid and identify seven additional sampling locations across four skeletal elements that yield adequate aDNA for most applications in human palaeogenetics. Our study provides a better perspective on DNA preservation across the human skeleton and takes a further step toward the more responsible use of ancient materials in human aDNA studies.Introduction Results Discussion Conclusions Methods - Sample selection, pre‑treatment, and bone powder generation - DNA extraction, library preparation, and sequencing - Evaluation criteria - Contamination estimates - Mapping - Calculations - Mixed effects modellin

    Note on SLE and logarithmic CFT

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    It is discussed how stochastic evolutions may be linked to logarithmic conformal field theory. This introduces an extension of the stochastic Loewner evolutions. Based on the existence of a logarithmic null vector in an indecomposable highest-weight module of the Virasoro algebra, the representation theory of the logarithmic conformal field theory is related to entities conserved in mean under the stochastic process.Comment: 10 pages, LaTeX, v2: version to be publishe

    Phase–Property Diagrams for Multicomponent Oxide Systems toward Materials Libraries

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    Exploring the vast compositional space offered by multicomponent systems or high entropy materials using the traditional route of materials discovery, one experiment at a time, is prohibitive in terms of cost and required time. Consequently, the development of high-throughput experimental methods, aided by machine learning and theoretical predictions will facilitate the search for multicomponent materials in their compositional variety. In this study, high entropy oxides are fabricated and characterized using automated high-throughput techniques. For intuitive visualization, a graphical phase–property diagram correlating the crystal structure, the chemical composition, and the band gap are introduced. Interpretable machine learning models are trained for automated data analysis and to speed up data comprehension. The establishment of materials libraries of multicomponent systems correlated with their properties (as in the present work), together with machine learning-based data analysis and theoretical approaches are opening pathways toward virtual development of novel materials for both functional and structural applications

    Assessing the perspective of well-being of older patients with multiple morbidities by using the LAVA tool-a person-centered approach

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    BACKGROUND: Older patients with multiple morbidities are a particularly vulnerable population that is likely to face complex medical decisions at some time in their lives. A patient-centered medical care fosters the inclusion of the patients’ perspectives, priorities, and complaints into clinical decision making. METHODS: This article presents a short and non-normative assessment tool to capture the priorities and problems of older patients. The so-called LAVA (“Life and Vitality Assessment”) tool was developed for practical use in seniors in the general population and for residents in nursing homes in order to gain more knowledge about the patients themselves as well as to facilitate access to the patients. The LAVA tool conceptualizes well-being from the perspectives of older individuals themselves rather than from the perspectives of outside individuals. RESULTS: The LAVA tool is graphically presented and the assessment is explained in detail. Exemplarily, the outcomes of the assessments with the LAVA of three multimorbid older patients are presented and discussed. In each case, the assessment pointed out resources as well as at least one problem area, rated as very important by the patients themselves. CONCLUSIONS: The LAVA tool is a short, non-normative, and useful approach that encapsulates the perspectives of well-being of multimorbid patients and gives insights into their resources and problem areas. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02342-3

    Decline of genetic diversity in ancient domestic stallions in Europe.

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    Present-day domestic horses are immensely diverse in their maternally inherited mitochondrial DNA, yet they show very little variation on their paternally inherited Y chromosome. Although it has recently been shown that Y chromosomal diversity in domestic horses was higher at least until the Iron Age, when and why this diversity disappeared remain controversial questions. We genotyped 16 recently discovered Y chromosomal single-nucleotide polymorphisms in 96 ancient Eurasian stallions spanning the early domestication stages (Copper and Bronze Age) to the Middle Ages. Using this Y chromosomal time series, which covers nearly the entire history of horse domestication, we reveal how Y chromosomal diversity changed over time. Our results also show that the lack of multiple stallion lineages in the extant domestic population is caused by neither a founder effect nor random demographic effects but instead is the result of artificial selection-initially during the Iron Age by nomadic people from the Eurasian steppes and later during the Roman period. Moreover, the modern domestic haplotype probably derived from another, already advantageous, haplotype, most likely after the beginning of the domestication. In line with recent findings indicating that the Przewalski and domestic horse lineages remained connected by gene flow after they diverged about 45,000 years ago, we present evidence for Y chromosomal introgression of Przewalski horses into the gene pool of European domestic horses at least until medieval times
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