Hyperammonemia decreases body fat content in rat

AbstractWe have developed an animal model of hyperammonemia consisting of feeding rats a diet containing 20% (w/w) ammonium acetate. Ingestion of this diet markedly affects carcass composition, with a 46% reduction in lipid content. The ammonium diet alters levels of several key compounds involved in lipid metabolism. Long-chain acylcarnitine is increased in liver by approx. 60% while free carnitine and acetylcarnitine are unaffected. The hepatic content of acetyl-CoA increases by approx. 50%. The level of ketone bodies in blood increases by 32% but remains unchanged in liver. Our data indicate that hyperammonemia alters lipid metabolism and results in a significant decrease in body lipid content

Very low frequency Syndromes

Dismorfología, Citogenética y Clínica: Resultados de estudios sobre los datos del ECEMCThe aim of this chapter is to summarize updated knowledge about the clinical characteristics, etiology, genetic and molecular aspects, as well as mechanisms involved in syndromes having very low frequency, in order to promote their better recognition. During the last five years, a total of 30 syndromes have been published in this chapter of the Boletín del ECEMC. This issue includes the following selected syndromes: Crouzon, Pfeiffer, Apert, Saethre-Chotzen, Carpenter and Muenke. All share craniosynostosis as the main clinical feature but also present with other birth defects, the most important being limb malformations, specially syndactyly and polydactyly. Over 100 syndromes with craniosynostosis have been described, usually involving multiple sutures, and several of them are associated with limb malformations. The clinical overlapping between those syndromes makes difficult to perform a neonatal diagnosis, based on their clinical findings. However, molecular genetic testing, specifically of the FRGR1-3 and TWIST1 genes, could help to establish the diagnosis of some of them. Early diagnosis is important for establishing the most suitable treatment for each patient, as well as to offer an accurate genetic counselling and the possibility of preimplantational and/or prenatal diagnosis.N

Documento sobre el Sector Agrícola

Plan Estratégico de Desarrollo del Estado Mérida (PEDEM) Documento sobre el Sector Agrícola Equipo Técnico: Coordinador: Prof. Alejandro Gutiérrez S. (CIAAL-ULA) Universidad de Los Andes: Daniel Anido (CIAAL - Plan II) Liliana Quintero (CIAAL - Plan II) Ligia García (CIAAL - Plan II) Alberto Grisolía (CIAAL) Juán Carlos Rivero (IGRN-ULA) EDA-Mérida-Gobernación: Econ. Angela Rosa García CORPOANDES: Econ. Marlene de OrtízAlgunas Características Importantes del Sector Agrícola del Edo. MéridaPotencialidad Agroecológica del Estado MéridaImportancia relativa del sector agrícola y agroindustrial en la economía del estadoAlgunas características socioeconómicas de la población rural del Estado MéridaLas características de la estructura productiva y su ubicación geográficaEl destino de la producciónPasado reciente, situación actual y nuevo entorno macroeconómico para la agricultura merideñaLos grandes objetivos a alcanzar para la agricultura del estado Mérida durante el período 1996-2002: Una imagen del escenario alternativo deseableProblemas a resolver para alcanzar los objetivos, lineamientos de política y acciones prioritariasBibliografí[email protected]@[email protected]@ula.ve, [email protected]@ula.veNivel monográfic

Plan estratégico del Estado Mérida

Artículo publicado en la Revista Provincia. Publicación trimestral del Centro Iberoamericano de Estudios Provinciales y Locales CIEPROL. Mérida-Venezuela. Junio de 1998. No 5 y [email protected] monográfic