The formation number of vortex rings formed in uniform background co-flow

The formation of vortex rings generated by an impulsively started jet in the presence of uniform background co-flow is studied experimentally to extend previous results. A piston–cylinder mechanism is used to generate the vortex rings and the co-flow is supplied through a transparent shroud surrounding the cylinder. Digital particle image velocimetry (DPIV) is used to measure the development of the ring vorticity and its eventual pinch off from the generating jet for ratios of the co-flow to jet velocity ($R_{v})$ in the range 0 – 0.85. The formation time scale for the ring to obtain maximal circulation and pinch off from the generating jet, called the formation number ($F$), is determined as a function of $R_{v}$ using DPIV measurements of circulation and a generalized definition of dimensionless discharge time or ‘formation time’. Both simultaneous initiation and delayed initiation of co-flow are considered. In all cases, a sharp drop in $F$ (taking place over a range of 0.1 in $R_{v}$) is centred around a critical velocity ratio ($R_{crit}$). As the initiation of co-flow was delayed, the magnitude of the drop in $F$ and the value of $R_{crit}$ decreased. A kinematic model based on the relative velocities of the forming ring and jet shear layer is formulated and correctly predicts vortex ring pinch off for $R_{v} \,{>}\, R_{crit}$. The results of the model indicate the reduction in $F$ at large $R_{v}$ is directly related to the increased convective velocity provided to the ring by the co-flow

Vortex ring pinchoff in the presence of simultaneously initiated uniform background co-flow

Vortex rings were formed with a piston-cylinder mechanism in the presence of uniform background co-flow supplied through a shroud surrounding the cylinder. The jet and co-flow were started simultaneously. Ratios of the co-flow to jet velocity (Rv) in the range 0–1 were considered. The formation number (F) as a function of Rv was determined using the procedure of Gharib et al. [J. Fluid Mech. 360, 121 (1998)] and a generalized definition of formation time. The results show a sharp decrease in F as Rv increases from 0.5–0.75, suggesting possible performance limitations for pulsed-jet propulsion

Thrust augmentation and vortex ring evolution in a fully pulsed jet

The time-averaged thrust of an incompressible fully pulsed jet containing a period of no flow between pulses is studied experimentally as a function of pulsing duty cycle Sr_L and the ratio of the ejected slug length (per pulse) to the jet diameter L/D. The parameter ranges investigated were 2≤L/D≤6 and 0.1≤Sr_L≤0.98. Significant thrust augmentation by pulsing was observed over the entire parameter range tested, both in terms of thrust compared to an equivalent steady jet with identical mass flux, denoted F_(SJ) >1, and in terms of thrust compared to an equivalent intermittent jet where vortex ring formation by pulsation was ignored, denoted F_(IJ) >1. F_(SJ) as high as 1.90 (90% thrust augmentation) was observed for the smaller L/D as Sr_L approached 1.0 (with larger F_(SJ) at lower Sr_L). The F_(IJ) results, which directly measured overpressure at the nozzle exit plane developed during vortex ring formation as the mechanism responsible for thrust augmentation, showed reduced augmentation at large L/D and Sr_L. The L/D dependence of F_(IJ) parallels single-pulse (Sr_L =0) results previously studied by the authors. The Sr_L dependence of F_(IJ) was linked to the interaction of forming vortex rings with vorticity from preceding pulses using digital particle image velocimetry (DPIV) measurements of the vorticity field. DPIV also revealed that the vortex rings tended to wander off axis and disintegrate as Sr_L became sufficiently large

Flow Patterns Around the Carapaces of Rigid-bodied, Multi-propulsor Boxfishes (Teleostei: Ostraciidae)

Boxfishes (Teleostei: Ostraciidae) are rigid-body, multi-propulsor swimmers that exhibit unusually small amplitude recoil movements during rectilinear locomotion. Mechanisms producing the smooth swimming trajectories of these fishes are unknown, however. Therefore, we have studied the roles the bony carapaces of these fishes play in generating this dynamic stability. Features of the carapaces of four morphologically distinct species of boxfishes were measured, and anatomically-exact stereolithographic models of the boxfishes were constructed. Flow patterns around each model were investigated using three methods: 1) digital particle image velocimetry (DPIV), 2) pressure distribution measurements, and 3) force balance measurements. Significant differences in both cross-sectional and longitudinal carapace morphology were detected among the four species. However, results from the three interrelated approaches indicate that flow patterns around the various carapaces are remarkably similar. DPIV results revealed that the keels of all boxfishes generate strong longitudinal vortices that vary in strength and position with angle of attack. In areas where attached, concentrated vorticity was detected using DPIV, low pressure also was detected at the carapace surface using pressure sensors. Predictions of the effects of both observed vortical flow patterns and pressure distributions on the carapace were consistent with actual forces and moments measured using the force balance. Most notably, the three complementary experimental approaches consistently indicate that the ventral keels of all boxfishes, and in some species the dorsal keels as well, effectively generate self-correcting forces for pitching motions—a characteristic that is advantageous for the highly variable velocity fields in which these fishes reside

Association of systemic anaplastic large cell lymphoma and active toxoplasmosis in a child

Introduction: Anaplastic large cell lymphoma is a subset of non-Hodgkin lymphoma and an unusual disease in children. Case Presentation: Herein we have reported a 7- year- old girl with a large necrotic skin ulcer on the chest caused by systemic form of anaplastic large-cell lymphoma and simultaneous active toxoplasmosis diagnosed by PCR on lymph node specimen. There were few reports showing a role for toxoplasma infection to cause some malignancies such as lymphoma in adults. Conclusions: Based to our knowledge, this has been the first report of simultaneous systemic anaplastic large cell lymphoma and active toxoplasmosis, documented by positive PCR on tissue biopsy in a child. This case report has suggested more attention to the accompanying Toxoplasma gondii infection as a probable cause of some types of lymphomas. © 2015, Iranian Journal of Cancer Prevention

The near wall effect of synthetic jets in a boundary layer

Copyright @ 2007 Elsevier Inc. All rights reserved.An experimental investigation to analyse the qualitative near wall effect of synthetic jets in a laminar boundary layer has been undertaken for the purpose of identifying the types of vortical structures likely to have delayed separation on a 2D circular cylinder model described in this paper. In the first instance, dye visualisation of the synthetic jet was facilitated in conjunction with a stereoscopic imaging system to provide a unique quasi three-dimensional identification of the vortical structures. Secondly, the impact of synthetic jet structures along the wall was analysed using a thermochromic liquid crystal-based convective heat transfer sensing system in which, liquid crystals change colour in response to the thermal footprints of a passing flow structure. Of the different vortical structures produced as a result of varying actuator operating and freestream conditions, the footprints of hairpin vortices and stretched vortex rings revealed a marked similarity with the oil flow pattern of a vortex pair interacting with the separation line on the cylinder hence suggesting that either of these structures was responsible in delaying separation. Conditions were established for the formation of the different synthetic jet structures in non-dimensional parameter space

Noninvasive Stem Cell Labeling Using USPIO Technique and their Detection with MRI

Background: To date, several imaging techniques to track stem cells are used such as positron emission tomography (PET), single photon emission computed tomography (SPECT), Bioluminescence imaging (BLI), fluorescence imaging, CT scan and magnetic resonance imaging (MRI). Although, overall sensitivity of MRI compared to SPECT and Bioluminescence techniques are lower, but due to high spatial resolution (~100 mm), long term three-dimensional imaging capability, in vivo quick access to images in three different sections, and noninvasiveness it is being used as the method of choice. Methods: The present study is the search results for authors and sources of information in the field of molecular and cellular imaging to examine the problems and perspectives about stem cells labeling with Ultrasmall Super Paramagnetic Iron Oxide (USPIO) and their tracking by MRI. Results: With the advancement of technology, including quantum physics, chemistry, and computer software, MRI with an excellent spatial resolution and contrast, is surpasses other imaging modalities in the analysis of anatomical and pathological features and images of all body tissues. From the other side, advances in the astronomical science, chemistry and nanotechnology, high biocompatibility and cytotoxicity of nanoparticles, and due to analysis in the metabolic pathways of iron made the procedure easier; however, there are still several fundamental questions in understanding the mechanism of biological molecules in the living cells including: 1- How to detect not only the location but also the performance of the labeled cells? Probably combination of USPIO nanoparticles with other reporter genes as contrast agents for MRI and PET can simultaneously be used to overcome these limitations 2) How to trace stem cells from pre-clinical models to translate to humans? Up to now, due to issues of bioethics, little studies have been done in this area. 3) Whether the transplanted stem cells that have reached the target tissue, will remain or migrate? Despite the fact that cell proliferation and exocytosis are two main factors for long term protection of USPIO nanoparticles inside cells, their signals cannot be received for a long time. 4) What mechanisms cause stem cells reaching the target tissue to react with their environment? And 5) what is the number of transplanted cells in live tissue, and what is their half-life? Conclusion: This study showed that USPIO nanoparticles can enter the cell with a clear dose without any adverse biological effects and could be detected by SWI and T2* techniques under MRI (1.5 Tesla) scanner for almost one month. MRI as a secure mean can illustrate with optimal resolution the spatial-resolution and three-dimensional positions of the stem cells. Keywords: Ultrasmall Super Paramagnetic Iron Oxide (USPIO), labeled stem cell, in vivo tracking, MRI