Assessing Causation in Breast Implant Litigation: The Role of Science Panels

In two recent cases, federal judges appointed panels of scientific experts to help assess conflicting scientific testimony regarding causation of systemic injuries by silicone gel breast implants. This article will describe the circumstances that gave rise to the appointments, the procedures followed in making the appointments and reporting to the courts, and the reactions of the participants in the proceedings

A synopsis of recent North American microtine rodents

http://deepblue.lib.umich.edu/bitstream/2027.42/56364/1/MP120.pd

Recurrence in generic staircases

The straight-line flow on almost every staircase and on almost every square tiled staircase is recurrent. For almost every square tiled staircase the set of periodic orbits is dense in the phase space

Heavily loaded ferrite-polymer composites to produce high refractive index materials at centimetre wavelengths

A cold-pressing technique has been developed for fabricating composites composed of a polytetrafluoroethylene-polymer matrix and a wide range of volume-fractions of MnZn-ferrite filler (0%–80%). The electromagnetic properties at centimetre wavelengths of all prepared composites exhibited good reproducibility, with the most heavily loaded composites possessing simultaneously high permittivity (180 ± 10) and permeability (23±2). The natural logarithm of both the relative complex permittivity and permeability shows an approximately linear dependence with the volume fraction of ferrite. Thus, this simple method allows for the manufacture of bespoke materials required in the design and construction of devices based on the principles of transformation optics

Searching for Dark Matter with Future Cosmic Positron Experiments

Dark matter particles annihilating in the Galactic halo can provide a flux of positrons potentially observable in upcoming experiments, such as PAMELA and AMS-02. We discuss the spectral features which may be associated with dark matter annihilation in the positron spectrum and assess the prospects for observing such features in future experiments. Although we focus on some specific dark matter candidates, neutralinos and Kaluza-Klein states, we carry out our study in a model independent fashion. We also revisit the positron spectrum observed by HEAT.Comment: 19 pages, 33 figure

Cognitive improvement in children with CKD after transplant

Icard P, Hooper SR, Gipson DS, Ferris ME. Cognitive improvement in children with CKD after transplant. Pediatr Transplantation 2010: 14:887–890. © 2010 John Wiley & Sons A/S.The primary purpose of this paper was to examine the cognitive functioning of children with CKD receiving transplantation to children with CKD not receiving transplantation, and a healthy control group. The sample included six children with CKD receiving transplant, 28 children with CKD being treated conservatively, and 23 healthy controls. All participants were administered intellectual (IQ) or developmental assessments at baseline and at a one-yr follow-up. Results revealed that children with CKD who had received transplant showed a significant increase in their intellectual/developmental functioning post transplant compared to children with CKD not receiving transplant. Although their overall intellectual/developmental level was not fully normalized, when compared with the healthy control group, the change scores for the transplant group reflected over a 12 point increase, moving the group from the borderline range to the low average range of functioning. In this regard, pediatric transplantation appears to have a positive impact on the intellectual and developmental functioning of children with CKD.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79239/1/j.1399-3046.2010.01359.x.pd

Decay of High-Energy Astrophysical Neutrinos

Existing limits on the non-radiative decay of one neutrino to another plus a massless particle (e.g., a singlet Majoron) are very weak. The best limits on the lifetime to mass ratio come from solar neutrino observations, and are \tau/m \agt 10^{-4} s/eV for the relevant mass eigenstate(s). For lifetimes even several orders of magnitude longer, high-energy neutrinos from distant astrophysical sources would decay. This would strongly alter the flavor ratios from the $\phi_{\nu_e}:\phi_{\nu_{\mu}}:\phi_{\nu_{\tau}} = 1:1:1$ expected from oscillations alone, and should be readily visible in the near future in detectors such as IceCube.Comment: 4 pages, 1 figure. References added. Version to appear in PR

Kaluza-Klein Dark Matter, Electrons and Gamma Ray Telescopes

Kaluza-Klein dark matter particles can annihilate efficiently into electron-positron pairs, providing a discrete feature (a sharp edge) in the cosmic $e^+ e^-$ spectrum at an energy equal to the particle's mass (typically several hundred GeV to one TeV). Although this feature is probably beyond the reach of satellite or balloon-based cosmic ray experiments (those that distinguish the charge and mass of the primary particle), gamma ray telescopes may provide an alternative detection method. Designed to observe very high-energy gamma-rays, ACTs also observe the diffuse flux of electron-induced electromagnetic showers. The GLAST satellite, designed for gamma ray astronomy, will also observe any high energy showers (several hundred GeV and above) in its calorimeter. We show that high-significance detections of an electron-positron feature from Kaluza-Klein dark matter annihilations are possible with GLAST, and also with ACTs such as HESS, VERITAS or MAGIC.Comment: 10 pages, 2 figure

The nervous system and chronic kidney disease in children

This paper provides a review of the literature on the nervous system involvement incurred by children and adolescents with chronic kidney disease (CKD), with a particular focus on neuropsychological functioning. In addition to an historical overview of earlier literature, published studies from the past 14 years that address both central and peripheral nervous system function in children with CKD are reviewed (1990–2003). These studies span work in neuroimaging, electrophysiology, and neuropsychology. A key focus for this review is on variables that might affect neurodevelopmental status in these children. The paper concludes with suggestions for achieving progress in the understanding of this complication of kidney disease in children