25,235 research outputs found

    Approximate theoretical performance evaluation for a diverging rocket

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    A simplified combustion model, which is motivated by available performance studies on the diverging rocket reactor, has been used as basis for an engine performance evaluation. Comparison with conventional rocket configurations shows that an upper performance limit for the diverging reactor is comparable with performance estimates for engines using an adiabatic work cycle. Development of the diverging reactor for engine applications may, however, offer some advantages for very hot, high-energy, propellant systems

    Which Fuel?

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    Tractor Fuel Costs

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    Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling

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    The relative roles of SULF1 and SULF2 enzymes in tumour growth are controversial, but short SULF1/SULF2 splice variants predominate in human mammary tumours despite their non-detectable levels in normal mammary tissue. Compared with the normal, the level of receptor tyrosine kinase (RTK) activity was markedly increased in triple-positive mammary tumours during later stages of tumour progression showing increased p-EGFR, p-FGFR1 and p-cMet activity in triple-positive but not in triple-negative tumours. The abundance of catalytically inactive short SULF1/SULF2 variants permits high levels of HS sulphation and thus growth driving RTK cell signalling in primary mammary tumours. Also observed in this study, however, was increased N-sulphation detected by antibody 10E4 indicating that not only 6-O sulphation but also N-sulphation may contribute to increased RTK cell signalling in mammary tumours. The levels of such increases in not only SULF1/SULF2 but also in pEGFR, pFGFR1, p-cMet and Smad1/5/8 signalling were further enhanced following lymph node metastasis. The over-expression of Sulf1 and Sulf2 variants in mammary tumour-derived MDA-MB231 and MCF7 cell lines by transfection further confirms Sulf1-/Sulf2-mediated differential modulation of growth. The short variants of both Sulf1 and Sulf2 promoted FGF2-induced MDA-MB231 and MCF7 in vitro growth while full-length Sulf1 inhibited growth supporting in vivo mammary tumour cell signalling patterns of growth. Since a number of mammary tumours become drug resistant to hormonal therapy, Sulf1/Sulf2 inhibition could be an alternative therapeutic approach to target such tumours by down-regulating RTK-mediated cell signalling

    Flow and acoustic characteristics of subsonic and supersonic jets from convergent nozzle

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    Acoustic and flow characteristics of subsonic and supersonic jets from convergent nozzle

    Damping of bulk excitations over an elongated BEC - the role of radial modes

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    We report the measurement of Beliaev damping of bulk excitations in cigar shaped Bose Einstein condensates of atomic vapor. By using post selection, excitation line shapes of the total population are compared with those of the undamped excitations. We find that the damping depends on the initial excitation energy of the decaying quasi particle, as well as on the excitation momentum. We model the condensate as an infinite cylinder and calculate the damping rates of the different radial modes. The derived damping rates are in good agreement with the experimentally measured ones. The damping rates strongly depend on the destructive interference between pathways for damping, due to the quantum many-body nature of both excitation and damping products.Comment: 5 pages, 4 figure

    Hybrid Superconductor-Quantum Point Contact Devices using InSb Nanowires

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    Proposals for studying topological superconductivity and Majorana bound states in nanowires proximity coupled to superconductors require that transport in the nanowire is ballistic. Previous work on hybrid nanowire-superconductor systems has shown evidence for Majorana bound states, but these experiments were also marked by disorder, which disrupts ballistic transport. In this letter, we demonstrate ballistic transport in InSb nanowires interfaced directly with superconducting Al by observing quantized conductance at zero-magnetic field. Additionally, we demonstrate that the nanowire is proximity coupled to the superconducting contacts by observing Andreev reflection. These results are important steps for robustly establishing topological superconductivity in InSb nanowires

    Unique Mass Texture for Quarks and Leptons

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    Texture specific quark mass matrices which are hermitian and hierarchical are examined in detail . In the case of texture 6 zeros matrices, out of sixteen possibilities examined by us, none is able to fit the low energy data (LED), for example, Vus=0.2196±0.0023V_{us} = 0.2196 \pm 0.0023, Vcb=0.0395±0.0017V_{cb} = 0.0395 \pm 0.0017, VubVcb=0.08±0.02\frac{V_{ub}}{V_{cb}} = 0.08 \pm 0.02, VtdV_{td} lies in the range 0.004−0.0130.004 - 0.013 (PDG). Similarly none of the 32 texture 5 zeros mass matrices considered is able to reproduce LED. In particular, the latest data from LEP regarding ∣Vub∣/∣Vcb∣(=0.093±0.016)|V_{ub}|/|V_{cb}|(=0.093\pm0.016) rules out all of them. In the texture 4 zeros case, we find that there is a unique texture structure for UU and DD mass matrices which is able to fit the data.Comment: 12 pages, LaTeX,some changes in the references,minor changes in the text,to appear in Phys Rev D(Rapid communications

    Causal Quantum Theory and the Collapse Locality Loophole

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    Causal quantum theory is an umbrella term for ordinary quantum theory modified by two hypotheses: state vector reduction is a well-defined process, and strict local causality applies. The first of these holds in some versions of Copenhagen quantum theory and need not necessarily imply practically testable deviations from ordinary quantum theory. The second implies that measurement events which are spacelike separated have no non-local correlations. To test this prediction, which sharply differs from standard quantum theory, requires a precise theory of state vector reduction. Formally speaking, any precise version of causal quantum theory defines a local hidden variable theory. However, causal quantum theory is most naturally seen as a variant of standard quantum theory. For that reason it seems a more serious rival to standard quantum theory than local hidden variable models relying on the locality or detector efficiency loopholes. Some plausible versions of causal quantum theory are not refuted by any Bell experiments to date, nor is it obvious that they are inconsistent with other experiments. They evade refutation via a neglected loophole in Bell experiments -- the {\it collapse locality loophole} -- which exists because of the possible time lag between a particle entering a measuring device and a collapse taking place. Fairly definitive tests of causal versus standard quantum theory could be made by observing entangled particles separated by ≈0.1\approx 0.1 light seconds.Comment: Discussion expanded; typos corrected; references adde
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