Inverse System in The Category of Intuitionistic Fuzzy Soft Modules

This paper begins with the basic concepts of soft module. Later, we introduce inverse system in the category of intutionistic fuzzy soft modules and prove that its limit exists in this category. Generally, limit of inverse system of exact sequences of intutionistic fuzzy soft modules is not exact. Then we define the notion  which is first derived functor of the inverse limit functor. Finally, using methods of homology algebra, we prove that the inverse system limit of exact sequence of intutionistic fuzzy soft modules is exact

The Universal Coefticient Theorem in the Category of Fuzzy Soft Modules

This paper begins with the basic concepts of chain comlexes of fuzzy soft modules. Later, we introduce short exact sequence of fuzzy soft modules and prove that split short exact sequence of fuzzy soft chain complex. Naturally, we want to investigate whether or not the universal coefficient theorems are satisfied in category of fuzzy soft chain complexes. However, in the proof of these theorems in the category of chain complexes, exact sequence of homology modules of chain complexes is used. Generally, sequence of fuzzy soft homology modules is not exact in fuzzy chain complexes. Therefore in this study, we construct exact sequence of fuzzy soft homology modules under some conditions. Universal coefficients theorem is proven by making use of this idea

Promoter methylation analysis of CDH1 and p14ARF genes in patients with urothelial bladder cancer

BACKGROUND/AIM: Urothelial bladder cancer arises from the accumulation of multiple epigenetic and genetic changes. We aimed to investigate the specificity and sensitivity of gene-specific promoter methylation of CDH1 and p14ARF genes in the early diagnosis of bladder cancer and compare those with other diagnostic tests in our population. PATIENTS AND METHODS: In the current study, 65 patients with urothelial bladder cancer and 35 controls without any history of cancer were recruited. Methylation profiles of CDH1 and p14ARF genes from tumor and urine samples were determined by methylation-specific polymerase chain reaction method. RESULTS: Methylation of CDH1 and p14ARF genes in tumor samples was 95.4% and 78.5%, respectively. The methylation frequencies were found to be 68.8% for CDH1 gene and 72.9% for p14ARF gene in urine samples. Sensitivities of CDH1, p14ARF and urine cytology were found to be 67.4%, 72.1% and 34.9%, respectively, while their specificities were 93.9%, 63.6% and 93.9%, respectively. CONCLUSION: Aberrant promoter methylation of CDH1 and p14ARF genes can be used to detect urothelial bladder cancer. In low-grade tumors, when compared with urine cytology, combined methylation analysis of CDH1 and p14ARF genes may not increase the sensitivity to identify malignant cells in urine samples

Роль операции продольной резекции желудка в обеспечении гликемического контроля у пациентов с сахарным диабетом 2-го типа и ожирением

Цель. Изучить корреляцию между контролем уровня гликемии и степенью снижения индекса массы тела у пациентов после бариатрической операции. Материалы и методы. Проведен контроль уровня обмена глюкозы у 84 пациентов с предиабетом и сахарным диабетом 2-го типа, страдающих патологическим ожирением, после операции уменьшения желудка. Результаты. Из 84 пациентов у 30 (35,7%) продолжительность заболевания сахарным диабетом 2-го типа составляла 1 год, у 27 (32,1%) – 10 лет, у 12 (14,3%) - более 10 лет. У 15 (17,9%) пациентов диагностирован предиабет. При изучении антропометрических показателей отмечено снижение массы тела на 38% после операции по сравнению с исходными показателями. Индекс массы тела (ИМТ) снизился с 46,8 (41,3 – 54,3) до 27,6 (25,4 – 30,9) кг/м2 (р = 0,001). Через 2 года после операции общее снижение массы тела по сравнению с исходными показателями составило 42%, а ИМТ снизился до 26,8 (23,1 – 28,4) кг/м2. Ремиссия сахарного диабета 2-го типа в сроки наблюдения 1 - 3 года отмечена у 82 (98,6%) пациентов (уровень гликированного гемоглобина менее 6,0%, глюкозы натощак менее 5,6 ммоль/л). Выводы. Результаты проведенного исследования показали, что продольная резекция желудка у больных с сахарным диабетом 2-го типа эффективна не только для уменьшения ИМТ, но и для коррекции метаболического синдрома. В послеоперационном периоде у них наблюдали стабильность показателей гликемии и углеводного обмена

Spectral Deconvolution of Fossil Tooth Enamel Electron Paramagnetic Resonance Spectrum

In this work the ESR method has been applied to determine the age of fossil tooth enamel found in Mingachevir archeological site (Azerbaijan, Mingachevir). The EPR spectrum of tooth enamel has been deconvoluted into four individual Gaussian lines. Equivalent dose (Absorbed dose in tooth enamel that was historically accumulated due to natural irradiation) calculated using dose-response curves of individual Gaussian lines shows significantly different values. Peak 1 (with g= 2.006848) gives a significantly lower, Peak 4 (with g=2.002942) a significantly higher value of absorbed dose. The use of integrated spectra gives lower absorption dose values than the use of differential spectra

Assessment of feasibility of projects for creating information and management systems of the electric power complex under conditions of uncertainty

Evaluating the feasibility of implementing proposed projects for creating information management systems (IMS) for industrial facilities is a complex procedure due to the uncertainty surrounding the accurate data about the prepared project during its implementation. Therefore, the application of decision support methods, based on soft computing and methodology, is deemed appropriate to address the difficulties arising from non-factors (uncertainty, non-determinism) in the evaluation of the implementation of proposed projects for IMS creation. Consequently, the use of non-deterministic interval methods has been proposed for the evaluation of the suitability of project proposals for creating information management systems under conditions of interval non-determinism, highlighting its advantages

First national survey of anti-tuberculosis drug resistance in Azerbaijan and risk factors analysis.

SETTING: Civilian population of the Republic of Azerbaijan. OBJECTIVES: To determine patterns of anti-tuberculosis drug resistance among new and previously treated pulmonary tuberculosis (TB) cases, and explore their association with socio-demographic and clinical characteristics. DESIGN: National cross-sectional survey conducted in 2012-2013. RESULTS: Of 789 patients (549 new and 240 previously treated) who met the enrolment criteria, 231 (42%) new and 146 (61%) previously treated patients were resistant to any anti-tuberculosis drug; 72 (13%) new and 66 (28%) previously treated patients had multidrug-resistant TB (MDR-TB). Among MDR-TB cases, 38% of new and 46% of previously treated cases had pre-extensively drug-resistant TB (pre-XDR-TB) or XDR-TB. In previously treated cases, 51% of those who had failed treatment had MDR-TB, which was 15 times higher than in relapse cases (OR 15.2, 95%CI 6-39). The only characteristic significantly associated with MDR-TB was a history of previous treatment (OR 3.1, 95%CI 2.1-4.7); for this group, history of incarceration was an additional risk factor for MDR-TB (OR 2.8, 95%CI 1.1-7.4). CONCLUSION: Azerbaijan remains a high MDR-TB burden country. There is a need to implement countrywide control and innovative measures to accelerate early diagnosis of drug resistance in individual patients, improve treatment adherence and strengthen routine surveillance of drug resistance

Комплексное пpименение минимaльно инвазивных методoв лечения осложненного острого тяжелого панкреатита

Percutaneous interventions for the purpose of sanation of cavities of pancreatogenic destruction can be one of the ways to treat pancreatic necrosis. This leads to a rapid cleansing of the cavities and is an objective method of monitoring the stages of treatment. We present a case of successful treatment of infected pancreatic necrosis using minimally invasive, percutaneous, X-ray endovascular methods. Procedures performed: superselective embolization of the upper and lower pancreaticoduodenal arteries, embolization of the gastroduodenal artery, embolization of the splenic artery, selective catheterization and embolization of the left gastric artery with microemboli and coils.Чрескожные вмешательства с целью санации полостей панкреатогенной деструкции могут быть oдним из спoсoбов лечения панкреонекроза. Это приводит к быстрому очищению полостей и является объективным методом контроля этапов лечения. Представлен случай успешного лечения инфицированного панкреонекроза с использованием минимально инвазивных вмешательств, чрескожных, рентгенэндоваскулярных методов. Выполнены: суперселективная эмбoлизация верхней и нижней поджелудочно-двенадцатиперстных артерий, эмболизация желудoчно-двенадцатиперстной артерии, эмболизация селезеночной артерии, селективная катетеризация и эмболизация левой желудoчной артерии микрoэмболами и спиралями