Sosialisasi Undang-Undang Administrasi Kependudukan

Undang-Undang Nomor : 23 Tahun 2006 tentang Administrasi Kependudukandisempurnakan dengan ditetapkannya Undang-Undang Nomor : 24 Tahun 2013tentang Perubahan Undang-Undang Nomor : 23 Tahun 2006 tentang AdministrasiKependudukan. Dalam perubahan ini telah diatur program digitalisasiadministrasi kependudukan, misalnya dengan adanya program e-KTP, KartuKeluarga dan lainnya. Dan juga program digitalisasi di bidang Kependudukan danCatatan Sipil (DUKCAPIL). Tujuan kegiatan ini adalah untuk memberikanmateri-materi yang berkenaan dengan administrasi kependudukan terutama yangberkenaan dengan hak dan kewajiban warga negara selaku penduduk, maupuntentang bagaimana telah terjadinya paradigma pelaksanaan administrasikependudukan pada saat sebelum era digitalisasi maupun setelah era digitalisasi.Apa yang disampaikan dalam kegiatan ini diharapkan dapat disebarluaskankepada warga yang lain, setidaknya yang berada di wilayah lingkungan terdekatyaitu di lingkungan Rukun Warga (RW) Kelurahan Pamulang Barat, KecamatanPamulang Kota Tangerang Selatan. Harapan yang ingin dicapai dalam kegiatanini agar mitra mendapatkan pengetahuan dan wawasan mengenaikependudukan.Undang-Undang Nomor : 23 Tahun 2006 tentang AdministrasiKependudukan disempurnakan dengan ditetapkannya UndangUndang Nomor : 24Tahun 2013 tentang Perubahan Undang-Undang Nomor : 23 Tahun 2006 tentangAdministrasi Kependudukan. Dalam perubahan ini telah diatur programdigitalisasi administrasi kependudukan, misalnya dengan adanya program e-KTP,Kartu Keluarga dan lainnya. Dan juga program digitalisasi di bidangKependudukan dan Catatan Sipil (DUKCAPIL).Kata kunci : Pengabdian, Administrasi Kependuduka

The state of EU sports law: lessons from UEFA’s ‘Financial Fair Play’ regulations

The EU’s sporting competence derives from the legal norm, established by the European Court of Justice, that requires that ‘sporting rules’ of sports governing bodies which have an economic impact and which breach the fundamental freedoms or competition law can only be justified if shown to be a proportionate response to an inherent need in the sport. However, the certainty of this norm is undermined by the EU’s subsequent Treaty competence for sport, a political compromise, which is ambiguous, and which in due course generated the European Commission’s sports policy, with its emphasis on governance and social dialogue. Consequently, EU sports law has evolved into ‘soft law’ which is far from coherent. This is demonstrated in the tolerance shown for certain of UEFA’s ‘sporting rules’, notably its Financial Fair Play Regulations, which restrict competition and lack proportionality yet have not attracted sanction from the European Commission (a sports law policy which could be characterised as not even constituting soft law but delegalisation)

Co-expression and modulation of neuronal and endothelial nitric oxide synthase in human endothelial cells

Despite originally identified in neurones, the neuronal type of nitric oxide synthase (nNOS) is present also in cardiac and skeletal myocytes. Whether nNOS is functionally expressed in human endothelial cells—as the endothelial enzyme (eNOS)—is unknown. Human umbilical vein endothelial cells (HUVEC) were studied under control culture conditions and after 48 h treatment with cytomix (human tumour necrosis factor-a, interferon-c and E. coli endotoxin).We tested: (i) localisation and expression of nNOS and eNOS proteins by immunostaining and immunoblotting; (ii) activity of nNOS and eNOS by measuring L-arginine to L-citrulline conversion with 1-(2-trifluoromethylphenyl) imidazole (TRIM), a specific nNOS antagonist, in sub-cellular fractions; (iii) intracellular cGMP levels, as a marker for nitric oxide production, after TRIM pre-treatment, by radioimmunoassay. nNOS protein was expressed in the cytosolic fraction and immunolocalised in cultured HUVEC, and co-localised with the eNOS protein in frozen sections of the human umbilical cord. nNOS protein contributed to total L-citrulline production as TRIM selectively and dose-dependently reduced L-citrulline synthesis in the cytosolic but not particulate fraction of HUVEC. Similarly, TRIM reduced intracellular cGMP content both at baseline and after stimulation with a calcium ionophore. Cytomix down-regulated the expression and function of both nNOS and eNOS while no inducible NOS (iNOS) was detected. In conclusion, a functional neuronal type of NOS is co-expressed with the endothelial NOS type in HUVEC, suggesting a possible role for nNOS in regulation of blood flow

Human parvovirus B19 infection in infancy associated with acute and chronic lymphocytic myocarditis and high cytokine levels: Report of 3 cases and review

Human parvovirus B19 infection is occasionally associated with acute lymphocytic myocarditis (ALM), Three infants with B19 virus-associated ALM were followed up clinically, histologically, and immunovirologically. Each infant had B19 virus DNA in the blood or B19 virus-specific IgM antibodies, Two infants with postnatal infection recovered after immunosuppressive therapy. The third infant with possible prenatal infection developed chronic persistent myocarditis associated with persistent B19 virus DNA in the blood. All 3 infants had increased levels of interferon-gamma, tumor necrosis factor-alpha, and interleukins -6 and -8, Four newborns with congenital B19 virus infection and 3 infants and children who had postnatally acquired B19 virus infection without myocarditis all had normal levels of these cytokines. These observations suggest that B19 virus infection in infancy causes ALM in some infants and children