Assessment of Methotrexate Efficacy in The Treatment of Ectopic Pregnancy

Aim:Our aim in this study was to assess efficacy of single-dose methotrexate (MTX) as medical treatment for ectopic pregnancy (EP) by evaluating the results of patients given this treatment.Materials and Methods:Between September 2016 and August 2017, the treatment outcomes of EP cases treated with MTX at Gazi Yaşargil Training and Research Hospital of Health Sciences University were evaluated retrospectively.Results:In total, 126 cases treated for EP were evaluated and 65 cases were included in the study. In cases administered a single dose of MTX, the success rate was 80%, the failure rate was 13.8%, and the emergency surgery rate was 6.2%. The overall success rate of the medical treatment was 90.7% for a second dose of MTX. An unsuccessful result was considered as less than a 15% reduction in the beta-human chorionic gonadotropin (β-hCG) level between 4 and 7 days after single dose MTX administration. In all cases, the rate of emergency surgery after treatment was 9.3%.Conclusions:In our study, success rates in patients with EP treated with MTX were 80% after a single dose and as high as 90.7% when a second dose was added

Bilateral ischemic lumbosacral plexopathy presenting as acute paraparesia due to vascular graft occlusion in a patient with leriche syndrome [Leriche sendromlu bir olguda vasküler greft oklüzyonu sonucu akut paraparezi Şeklinde prezente olan bilateral ıskemik lumbosakral pleksopati]

Acute ischemia of peripheral nerves generally results from occlusion of a main proximal limb artery or from occlusion of many distal arteries. The rareness of such neuropathies can be explained by the relative resistance of peripheral nerves to ischemia. Leriche syndrome is an aortoiliac occlusive disease that is known to cause neurologic complications such as ischemic neuropathy and spinal cord ischemia. Here, we present a man aged 55 years with bilateral lumbosacral plexopathy that presented as acute paraparesia due to thrombotic occlusion of an axillobifemoral graft, which was performed for the treatment of Leriche syndrome. © 2017, Ege University Press. All rights reserved

Anesthetic management of Guillain-Barré syndrome in pregnancy

PubMed ID: 17572328We report the case of a 23-year-old woman who was diagnosed with an axonal type of Guillain-Barré syndrome at 16 weeks' gestation. The patient had severe motor loss but she was treated effectively with intravenous immunoglobulin, and she underwent cesarean delivery with epidural anesthesia at full term. © 2007 Elsevier Inc. All rights reserved

Comparison of three different medical treatments of retained placenta in cattle

in cattle, the fetal membranes are passed spontaneously within 2-12 hours after labor. When this physiological event fails to occur within the said period of time they are considered as retained placenta (Drillich et al. 2003). Retained placenta is more common in cattle than in other species, and is encountered in 8 % of cows giving normal birth and 25-55% of cows undergoing difficult labor (Laven and Peters, 1996)

Comparison of three different medical treatments of retained placenta in cattle

in cattle, the fetal membranes are passed spontaneously within 2-12 hours after labor. When this physiological event fails to occur within the said period of time they are considered as retained placenta (Drillich et al. 2003). Retained placenta is more common in cattle than in other species, and is encountered in 8 % of cows giving normal birth and 25-55% of cows undergoing difficult labor (Laven and Peters, 1996)

Cerebral venous thrombosis and Turner Syndrome: A rare reported association

PubMed ID: 26625661Cerebral venous thrombosis and Turner Syndrome: a rare reported association: Turner Syndrome is the only known viable chromosomal monosomy, characterised by the complete or partial absence of an X chromosome. It's the most common chromosomal abnormality in females. Apart from the well known dysmorphic features of the syndrome, it has been associated with a number of vascular pathologies; mainly involving the cardiovascular, renovascular, peripheral vascular and cerebrovascular system. It seems striking that thromboembolism is not considered as a feature of the syndrome. Most of the thromboembolism cases are related to the arterial vascular system; except for some rare reported portal venous thrombosis cases, peripheral venous thrombosis cases and to the best of our knowledge a single case of cerebral venous thrombosis with Dandy Walker malformation and polymicrogyria. We herein report a cerebral venous thrombosis case with Turner Syndrome. With no other found underlying etiology, we want to highlight that Turner Syndrome, itself, may have a relationship not only with the cerebral arterial vascular system pathologies but also with the cerebral venous thrombosis

Withdrawal reflexes in adductor muscles elicited by electrical and magnetic stimulation of the obturator nerve

PubMed ID: 18816621The withdrawal reflex in the short head of the biceps femoris muscle after electrical stimulation of the sural nerve at the ankle has been investigated in numerous studies. These studies have described two distinct responses: early (R-II) and late (R-III). However, withdrawal reflex activity of the adductor muscles in the legs has not been studied systematically. Adductor muscle reflex activity is important because it can produce serious clinical problems, such as adductor spasticity and spasms, during bladder surgery. The present study examined withdrawal reflex features of adductor muscles obtained by electrical and magnetic stimulation of the obturator nerve (ON) in 34 normal healthy subjects. Early adductor muscle withdrawal reflex responses were elicited by ipsilateral ON electrical stimulation with a mean latency of 45.7 ± 2.0 ms (responses in 94% of subjects). Reflex responses were also obtained using magnetic stimulation at a similar incidence rate. Contralateral ON electrical stimulation resulted in a similar reflex, but with a lower incidence. ON and femoral nerve electrical and magnetic coil stimulation produced similar low-incidence responses in the vastus medialis. These findings indicate that short latency adductor withdrawal reflexes are easily obtained on both sides following electrical or magnetic stimulation of the ON, and they can be elicited by both nociceptive and nonnociceptive stimuli. These reflexes prepare the body for a proper response to incoming signals and likely serve to protect the pelvic floor and pelvic organs. © 2008 Wiley Periodicals, Inc