Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration: a systematic review and intervention coding protocol.

INTRODUCTION: Little is known about how early (eg, commencing antenatally or in the first 12 months after birth) obesity prevention interventions seek to change behaviour and which components are or are not effective. This study aims to (1) characterise early obesity prevention interventions in terms of target behaviours, delivery features and behaviour change techniques (BCTs), (2) explore similarities and differences in BCTs used to target behaviours and (3) explore effectiveness of intervention components in preventing childhood obesity. METHODS AND ANALYSIS: Annual comprehensive systematic searches will be performed in Epub Ahead of Print/MEDLINE, Embase, Cochrane (CENTRAL), CINAHL, PsycINFO, as well as clinical trial registries. Eligible randomised controlled trials of behavioural interventions to prevent childhood obesity commencing antenatally or in the first year after birth will be invited to join the Transforming Obesity in CHILDren Collaboration. Standard ontologies will be used to code target behaviours, delivery features and BCTs in both published and unpublished intervention materials provided by trialists. Narrative syntheses will be performed to summarise intervention components and compare applied BCTs by types of target behaviours. Exploratory analyses will be undertaken to assess effectiveness of intervention components. ETHICS AND DISSEMINATION: The study has been approved by The University of Sydney Human Research Ethics Committee (project no. 2020/273) and Flinders University Social and Behavioural Research Ethics Committee (project no. HREC CIA2133-1). The study's findings will be disseminated through peer-reviewed publications, conference presentations and targeted communication with key stakeholders. PROSPERO REGISTRATION NUMBER: CRD42020177408

Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysis of behavioural interventions for the prevention of early childhood obesity.

INTRODUCTION: Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted an increase in very early childhood obesity prevention trials worldwide. Combining the individual participant data (IPD) from these trials will enhance statistical power to determine overall effectiveness and enable examination of individual and trial-level subgroups. We present a protocol for a systematic review with IPD meta-analysis to evaluate the effectiveness of obesity prevention interventions commencing antenatally or in the first year after birth, and to explore whether there are differential effects among key subgroups. METHODS AND ANALYSIS: Systematic searches of Medline, Embase, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycInfo and trial registries for all ongoing and completed randomised controlled trials evaluating behavioural interventions for the prevention of early childhood obesity have been completed up to March 2021 and will be updated annually to include additional trials. Eligible trialists will be asked to share their IPD; if unavailable, aggregate data will be used where possible. An IPD meta-analysis and a nested prospective meta-analysis will be performed using methodologies recommended by the Cochrane Collaboration. The primary outcome will be body mass index z-score at age 24±6 months using WHO Growth Standards, and effect differences will be explored among prespecified individual and trial-level subgroups. Secondary outcomes include other child weight-related measures, infant feeding, dietary intake, physical activity, sedentary behaviours, sleep, parenting measures and adverse events. ETHICS AND DISSEMINATION: Approved by The University of Sydney Human Research Ethics Committee (2020/273) and Flinders University Social and Behavioural Research Ethics Committee (HREC CIA2133-1). Results will be relevant to clinicians, child health services, researchers, policy-makers and families, and will be disseminated via publications, presentations and media releases. PROSPERO REGISTRATION NUMBER: CRD42020177408

Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysis of behavioural interventions for the prevention of early childhood obesity

Introduction Behavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted an increase in very early childhood obesity prevention trials worldwide. Combining the individual participant data (IPD) from these trials will enhance statistical power to determine overall effectiveness and enable examination of intervention-covariate interactions. We present a protocol for a systematic review with IPD meta-analysis to evaluate the effectiveness of obesity prevention interventions commencing antenatally or in the first year after birth, and to explore whether there are differential effects among key subgroups

Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration: a systematic review and intervention coding protocol

Introduction Little is known about how early (e.g., commencing antenatally or in the first 12 months after birth) obesity prevention interventions seek to change behaviour and which components are or are not effective. This study aims to 1) characterise early obesity prevention interventions in terms of target behaviours, delivery features, and behaviour change techniques (BCTs), 2) explore similarities and differences in BCTs used to target behaviours, and 3) explore effectiveness of intervention components in preventing childhood obesity

Experimental Investigation on Heat Transfer of Silver-Oil Nanofluid in Concentric Annular Tube

In order to examine the laminar convective heat transfer of nanofluid, experiments carried out using silver-oil nanofluid in a concentric annulus with outer constant heat flux as boundary condition. Silver-oil nanofluid prepared by Electrical Explosion of Wire technique and observed no nanoparticles agglomeration during nanofluid preparation process and carried out experiments. The average size of particles established to 20 nm. Nanofluids with various particle weight fractions of 0.12%wt., 0.36%wt. and 0.72%wt. were employed. The nanofluid flowing between the tubes is heated by an electrical heating coil wrapped around it. The effects of different parameters such as flow Reynolds number, diameter ratio and nanofluid particle concentration on heat transfer coefficient are studied. Results show that, heat transfer coefficient  and Nusselt number increased by using naanofluid instead of pure oil. Maximum enhancement of heat transfer coefficient occurs in 0.72% wt. also results indicate that heat transfer coefficient  increase slightly by using low wt. concentration of nanofluids

An empirical investigation on Cu/Ethylene Glycol nanofluid through a concentric annular tube and proposing a correlation for predicting Nusselt number

The investigation indicates an experimental study on the convective heat transfer of Cu/Ethylene Glycol nanofluid flow inside a concentric annular tube with constant heat flux boundary condition and proposes a novel correlation for the prediction of Nusselt number. For extending the previous study by Jafarimoghaddam et al., we selected the nanoparticles with the average size of 20 nm and also other conditions of the experiment are based on Jafarimoghaddam et al. (2016) [1]. The applied nanofluid was prepared by Electrical Explosion of Wire technique with no accumulation during the experiment. The tube was heated using an electrical heating coil covered it. The effects of different parameters such as flow Reynolds number and nanofluid particle concentration on heat transfer coefficient are studied. The acquired experimental data were used to establish a correlation for predicting Nusselt number of nanofluid flow inside the annular tube. This correlation has been presented by using the exponential regression analysis and least square method. Correlation is valid for Cu/Base Ethylene Glycol nanofluid flow with the volume concentrations between 0.011 and 0.171 in the hydrodynamically fully developed laminar flow regime with Re < 160 which is most applicable in micro heat sinks

Energy and exergy analysis of a photovoltaic thermal (PV/T) system using nanofluids: An experimental study

This paper aims to investigate the electrical, thermal and exergy efficiencies of a photovoltaic/thermal (PV/T) system cooled by Ag/water nanofluid. The utilized nanofluid was prepared by a one-step method of electrical explosion of wire (EEW) and was tested for long-term stability and uniformity. The performance of the PV/T system was measured by considering a wide range of parameters to determine key performance indicators such as electrical and thermal energy efficiency as well as exergy efficiency of the system. The effects of mass flow (i.e. different flow regimes of laminar, transient, and turbulent) on efficiencies were studied. The results showed that using nanofluids for cooling of the PV/T system can enhance both the energy and exergy efficiencies of the system significantly. It was also found that this positive impact is more pronounced by increasing the concentration of the nanofluid and increasing the flow rate (i.e. moving towards a turbulent flow). By using 4 wt% nanofluid (with turbulent flow) the power output of the panel increased by similar to 35% and similar to 10% compared to when no cooling and water cooling were applied respectively; and the exergy efficiency was also determined to be 50% and 30% higher than when no cooling and water cooling were used, respectively