Serum SCUBE-1 levels and return of spontaneous circulation following cardiopulmonary resuscitation in adult patients

Background SCUBE 1-has been used as a biomarker for the diagnoses of myocardial infarction, stroke, mesenteric ischemia, and gastric cancer in some recent studies. In this study, we investigated the relationship between serum SCUBE-1 levels and return of spontaneous circulation (ROSC) in patients who received cardiopulmonary resuscitation (CPR). Methods Patients over 18 years of age who were not pregnant and received CPR were divided into two groups: those who achieved ROSC and those who died. There were 25 patients in each group. SCUBE-1 and other routine biochemical parameters were studied in blood samples taken at the time of admission. Results There was no significant difference between the age and gender distribution of the patients between the two groups. The SCUBE-1 value of the ROSC group was significantly higher than that of the non-survivor group ( p ˂ 0.05). At a cut-off value of 9 ng/mL, SCUBE-1 had a sensitivity of 100%, a positive predictive value of 65.8%, specificity of 48%, and a negative predictive value of 100% in predicting ROSC. Conclusions The SCUBE-1 values were found to be significantly higher in the ROSC group compared with the non-survivor group

The Overdose Entoxication of Alprazolam, Purposing Suicide

Alprazolam (Xanax) is a triazolobenzodiazepine derivative, mainly usedas an anxiolytic and antidepressant, but also efficient in the treatment ofagoraphobia, panic attacks and panic disorders. Daily doses of 0.75–4 mgare effective for generalized anxiety, while daily doses of 6–9 mg have beenused for phobic and panic disorders. High-dose benzodiazepines classicallyinduce bradicardia in heart. And also, benzodiazepines are known to reducemyocardial contractility and increase myocardial blood flow: a reducedmyocardial function may compromise the hemodynamic status even further.In this study we tried to investigate the central nervous system and cardiaceffects that has been seen in high doses alprazolam intoxication cases withthe help of the literatures. Here in, we presented three cases of high dosesalprazolam intoxication

Possibilities of early pregnancy diagnosis by using blood progesteron Test in Kilis cows

Bu çalışmada, saha şartlarında Kilis Sığırlarında kan serumu progesteron testinin erken gebelik teşhisinde kullanım imkanının araştırılması amaçlanmıştır. Çalışma materyalini, yapılan suni tohumlamanın 40. gününde Hatay’ın Yayladağ ilçesi Aydınbahçe köyündeki 17 yetiştiriciye ait olan 21 Kilis ineğinden alınan kan örnekleri oluşturmuştur Kan örneklerinde progesteron analizi yapılmıştır. Tohumlamadan 90 gün sonra gebelik tanısı için uterus içeriğinin rektal palpasyonu yapılmıştır. Progesteron düzeyi gebe olduğu tahmin edilenlerde 2.910 ±0.6709 ng/ml, gebe olmadığı anlaşılanlarda 0.65 ±0.740 ng/ml olarak hesaplanmıştır. Kilis sığırlarında sun’i tohumlamanın 40. günündeki kan progesteron düzeyine göre gebe olanların % 81.25, olmayanların ise %100 doğrulukla belirlenmesinin mümkün olduğu sonucuna varılmıştır.In the research it was aimed to investigate possibilities of using of blood serum progesterone test in early pregnancy diagnosis in Kilis cows. The material of the study was formed by blood samples collected from 20 Kilis cows which were belong to 17 farmers of Aydınbahçe village of Yayladağ district of Hatay province, on the $40^ {th}$ day of artificial insemination. Progesteron was analysed in the serum of blood samples. Pregnancy was estimated by progesteron concentration in the samples. Pregnancy was confirmed on the 90th days after insemination by rectal palpation of the uterine contents. Progesterone levels of pregnant and non-pregnant cows on the day $40^ {th}$ of insemination were calculated as 2.910 ±0.6709 ng/ml, and 0.65 ±0.740 ng/ml, respectively. It was concluded that it is possible to determine pregnant and non pregnant ones at accuracy 81.25 % and 100%, respectively according to blood progesteron levels at the $40^ {th}$ day of insemination

Hand and wrist ınjuries caused by glass cuts: accidental or due to sudden anger?

ObjectivesTraumatic hand and wrist injuries are the type of injuries commonly seen in the emergency department (ED). Hand and wrist injuries related to punching windows due to sudden discomposes are frequent in Turkey. the aim of this study was to analyze clinical and demographic specifications of hand and wrist injuries related to glass cuts and their underlying causes.MethodsThe patient files who presented to the Dicle University Hospital ED (Diyarbakır-Turkey) with injuries due to glass cuts have been examined. Demographic data of the patients have been recorded in the standard work form and then were analyzed.ResultsOne hundred and fifty four patients were included in the study. 53.8% of the patients constituted those who punched on the glass during an angry episode. Punching on the glass was more frequently observed in men (n=81, 97.6%), with cuts to the right hand being the most frequent type of resulting injury (n=65, 78.3%). Twenty four (28.9%) of the patients with injuries related to glass punching were under the influence of alcohol during the incidents and injury rates of radial artery, ulnar nerve, median nerve and ulnar artery have been found considerably higher in this group.ConclusionsA thorough artery, nerve and tendon examination of the patients presenting to the ED with hand and wrist injuries needed to be performed, and especially for those under the influence of alcohol in order to prevent functional losses of the underlying structures.AmaçTravmatik el ve el bileği yaralanmaları acil serviste yaygın görülen yaralanmalardır. Ani öfkelenmeye bağlı cama yumruk atma ile ilişkili el ve el bileği yaralanmaları ülkemizde sıktır. Bu çalışmanın amacı oluş nedenlerine göre cam kesisi ile ilişkili el ve el bileği yaralanmalı hastalarda klinik ve demografik özellikleri analiz etmektir.Gereç ve YöntemDicle Üniversitesi Tıp Fakültesi Acil Servisi’ne cam kesisine bağlı yaralanma nedeniyle başvuran hastalar çalışmaya dahil edildi. Hastaların demografik verileri standart çalışma formuna kaydedildi. Demografik veriler istatistiksel olarak analiz edildi.BulgularÇalışmaya 154 hasta dahil edildi. Hastaların %53.8’I ani sinirlenmeye bağlı olarak cama yumruk atan hastalardı. Cama yumruk atma erkeklerde daha sık gözlendi (n=81, %97.6), yumruk atan grupta sağ el yaralanması daha sık görüldü (n=65, %78.3). Cama yumruk atma ile ilişkili yaralanmalı 24 hasta (%28.9) alkollüydü ve bu hastalarda radial arter, ulnar sinir, median sinir ve ulnar arter yaralanması anlamlı düzeyde yüksek bulundu.SonuçEl ve el bileği yaralanması nedeniyle acil servise başvuran hastaların damar, sinir ve tendon muayenelerinin dikkatli yapılması, özellikle alkollü hastalarda bu anatomik yapıların yaralanmalarının birlikte olabileceği, sonrasında ciddi fonksiyon kayıplarına yol açmaması için erken dönemde kontrollerinin yapılması sağlanmalıdır