279 research outputs found

    Using primary instability analysis for determination of apparent liquid viscosity at jet breakup atomizing non-Newtonian Fluids

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    An internal mixing twin-fluid atomizer used for the application of cavity wax in automotive engineering is investigated. At typical pressures of 100 bars the wax material is atomized into a chamber and mixed with air at elevated pressures between 4 and 6 bars. The formed two-phase flow is further flowing along a straight tube and finally discharging through a number of radially arranged orifices undergoing a secondary atomization process. The original aim of these investigations is to provide inlet and boundary conditions for numerical simulations of the unsteady film formation on the substrate. Applying a number of optical measuring techniques, the initial secondary disintegration process, initial droplet velocities and droplet size distributions could be determined. In general, it was found that at typical distances between 10 and 20 mm between nozzle and target surface the disintegration process is not yet completely finished. Due to high initial velocities of more than 100 m/s in the spray centre, the wax material deposits to a large extent in the form of ligaments. Therefore, the measured droplet size distributions can only be taken as a rough indication for the length scales of the droplets and ligaments

    Toward the development of a virtual spray test-rig using the Smoothed Particle Hydrodynamics method

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    In this work we present the numerical simulation of air-assisted liquid atomization at high pressure us- ing the Smoothed Particle Hydrodynamics (SPH) method. Different post-processing tools are applied to facilitate the comparison with experimental observations. This allows to quantitatively validate the nu- merical method against the experiment, in terms of (i) frequency of the Kelvin–Helmholtz instability that develops on the jet surface, and (ii) statistical distribution of the jet intact length. The qualitative com- parison also shows a good prediction of the jet global instability and of the fragmented liquid lumps, with regards to length and time scales. In addition, the post-processing tools also give access to the local parameters of the generated spray in the vicinity of the nozzle, which are not easily accessible in a real experiments. Using these tools, 1D profiles and 2D maps of the liquid phase properties such as the vol- ume fraction, the droplet concentration, the Sauter Mean Diameter (SMD) and the droplet sphericity are presented. Because of the Lagrangian nature of the SPH method, it is also possible to monitor the whole atomization cascade as a causal tree, from the primary instabilities to the spray characteristics. This tree contains various information such as the fragmentation spectrum and the breakup activity, which are of great interest for researchers and engineers. Hence, the capability of the Smoothed Particle Hydrody- namics (SPH) method for simulating air-assisted atomization at high ambient pressure is demonstrated as well as its applicability to realistic configurations. This is a first step towards the development of a complete virtual spray test-rig

    Autoantibodies to aS1-Casein Are Induced by Breast-Feeding

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    Background: The generation of antibodies is impaired in newborns due to an immature immune system and reduced exposure to pathogens due to maternally derived antibodies and placental functions. During nursing, the immune system of newborns is challenged with multiple milk-derived proteins. Amongst them, caseins are the main constituent. In particular, human aS1-casein (CSN1S1) was recently shown to possess immunomodulatory properties. We were thus interested to determine if auto-antibodies to CSN1S1 are induced by breast-feeding and may be sustained into adulthood. Methods: 62 sera of healthy adult individuals who were (n = 37) or were not (n = 25) breast-fed against human CSN1S1 were investigated by a new SD (surface display)-ELISA. For cross-checking, these sera were tested for anti Epstein-Barr virus (EBV) antibodies by a commercial ELISA. Results: IgG-antibodies were predominantly detected in individuals who had been nursed. At a cut-off value of 0.4, the SDELISA identified individuals with a history of having been breast-fed with a sensitivity of 80% and a specificity of 92%. Under these conditions, 35 out of 37 sera from healthy donors, who where breast-fed, reacted positively but only 5 sera of the 25 donors who were not breast-fed. The duration of breast-feeding was of no consequence to the antibody reaction as some healthy donors were only short term breast-fed (5 days minimum until 6 weeks maximum), but exhibited significant serum reaction against human CSN1S1 nonetheless. Conclusion: We postulate that human CSN1S1 is an autoantigen. The antigenicity is orally determined, caused by breastfeeding, and sustained into adulthood

    Link between BMP expression and clinical outcome in breast carcinomas

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    Vectorial Control of Magnetization by Light

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    Coherent light-matter interactions have recently extended their applications to the ultrafast control of magnetization in solids. An important but unrealized technique is the manipulation of magnetization vector motion to make it follow an arbitrarily designed multi-dimensional trajectory. Furthermore, for its realization, the phase and amplitude of degenerate modes need to be steered independently. A promising method is to employ Raman-type nonlinear optical processes induced by femtosecond laser pulses, where magnetic oscillations are induced impulsively with a controlled initial phase and an azimuthal angle that follows well defined selection rules determined by the materials' symmetries. Here, we emphasize the fact that temporal variation of the polarization angle of the laser pulses enables us to distinguish between the two degenerate modes. A full manipulation of two-dimensional magnetic oscillations is demonstrated in antiferromagnetic NiO by employing a pair of polarization-twisted optical pulses. These results have lead to a new concept of vectorial control of magnetization by light

    Oscillatory Shear Flow-Induced Alignment of Lamellar Melts of Hydrogen-Bonded Comb Copolymer Supramolecules

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    In this work we present the orientational behavior of comb copolymer-like supramolecules P4VP(PDP)1.0, obtained by hydrogen bonding between poly(4-vinylpyridine) and pentadecylphenol, during large-amplitude oscillatory shear flow experiments over a broad range of frequencies (0.001-10 Hz). The alignment diagram, presenting the macroscopic alignment in T/TODT vs ω/ωc, contains three regions of parallel alignment separated by a region of perpendicular alignment. For our material, the order-disorder temperature TODT = 67 °C and ωc, the frequency above which the distortion of the chain conformation dominates the materials’ viscoelasticity, is around 0.1 Hz at 61 °C. For the first time flipping from a pure transverse alignment via biaxial transverse/perpendicular alignment to a perpendicular alignment as a function of the strain amplitude was found.

    The Effectiveness of Contract Farming for Raising Income of Smallholder Farmers in Low- and Middle-Income Countries: a Systematic Review

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    Contract farming is used by an increasing number of firms as a preferred modality to source products from smallholder farmers in low and middle-income countries. Quality requirements of consumers, economies of scale in production or land ownership rights are common incentives for firms to offer contractual arrangements to farmers. Prices and access to key technology, key inputs or support services are the main incentives for farmers to enter into these contracts. There is great heterogeneity in contract farming, with differences in contracts, farmers, products, buyers, and institutional environments. The last decade shows a rapid increase in studies that use quasi-experimental research designs to assess the effects of specific empirical instances of contract farming on smallholders. The objective of this systematic review was to distill generalised inferences from this rapidly growing body of evidence. The review synthesised the studies in order to answer two questions: 1: What is known about the effect size of contract farming on income and food security of smallholder farmers in low- and middle-income countries? 2: Under which enabling or limiting conditions are contract farming arrangements effective for improving income and food security of smallholders
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