Synchronous, Multiple Primary Lung Cancers: A Report of Three Cases

Multiple primary lung cancers (MPLC) are named synchronous if determined simultaneously with the index tumor, and metachronous if the second tumor is diagnosed with an accepted time after the first tumor. It is important for both the rate of survival and treatment alternatives to differentiate synchronous MPLCs from the metastases of the primary lung tumors, and also from the multiple pulmonary metastases of the extra pulmonary tumors. In this study, clinical characteristics, diagnosis and treatment processes of three synchronous MPLC cases diagnosed in our department were assessed

Impact of cognitive functions on the quality of spirometry performance in patients with COPD

OBJECTIVE: We researched the relationship between the cognitive scores and the error codes which determine pulmonary function test (PFT) compliance accompanied by the phenotypic findings of chronic obstructive pulmonary disease (COPD) patients. MATERIALS AND METHODS: Patients in a stable condition with COPD, who were diagnosed with the criteria recommended in the international guidelines, were included in the study. PFTs were requested from all the patients during the regular outpatient admission. The following tests were applied to all the patients in a 30-min test session; COPD assessment test, modified British Medical Research Council and neurophysiological tests (Mini-Mental Test, Trail Making Test Part A and B, Clock Drawing Test, Straight and Backward Digit Span, Brown Peterson Task and Verbal Fluency Test). We analyzed the statistical relationship between data collected after cognitive tests and PFT quality data. RESULTS: The study was concluded with a total of 70 patients. When the PFT evaluations of the patients were examined, the percentage of patients who correctly fulfilled the repeatability criteria was found as 28%, who met the acceptability criteria as 57%, and who correctly fulfilled both criteria as 14%. The relationship between the results of patients, who fulfilled both repeatability and acceptability criteria correctly and incorrectly at the same time, with the backward digit span test results was found to be significant (P < 0.05). It was found that the Mini-Mental Test was significantly better in those who performed all of the repeatability and acceptability criteria without errors than the other groups. When the PFT criteria of the patients were evaluated according to the cognitive test results, it was determined that the relationship between the Mini-Mental Test and the results of performing the repeatability and acceptability criteria together was found to be statistically significant (P < 0.05). DISCUSSION AND CONCLUSION: Error codes that identify the compliance in PFTs could be used as predictors of cognitive impairment in COPD

Effect of low-intensity pulmonary rehabilitation program on quality of life and pulmonary functions in patients with stable chronic obstructive pulmonary disease

OBJECTİVES: The effectiveness of low-intensity pulmonary rehabilitation program applied patients with chronic obstructive pulmonary disease (COPD) in terms of exercise capacity, dyspnea scale, life quality and respiratory muscle strength. METHODS: The study included 30 patients with COPD. The program was 3 days in a week, for a 6 weeks period between December 1st 2012 and August 31st 2013. Arterial blood gas (ABG), 6 minute walking test (SMWT), respiratory function tests and respiratory muscle strength were evaluated before and after treatment. St George's breathing questionnaire (SGRQ) was used to assess quality of life. The dyspnea scores were assessed by the Modified Medical Research Council (mMRC) and the COPD Assessment Test (CAT). Patient approvals were obtained for the study. For analysis of results kolmogorov smirnov test, shapiro – wilk test, wilcoxon test and sample ttest were used. RESULTS: Of 30 patients participated in our study, 26 completed the treatment program. There were increases in SMWT distance (P = 0.049), forced expiratory volume in one second, and forced expiratory flow (FEF 25-75) value (P < 0.05); and decreases in mMRC dyspnea scale score (P = 0.001), CAT score (p=0.003) and SGRQ score (P <= 0.001). Maximum inspiratory pressure and maximum expiratory pressure values and ABG parameters did not show significant change. CONCLUSION: Low intensity pulmonary rehabilitation therapy has positive effects on exercise capacity, dyspnea scale, walking distance, and quality of life. Patient compliance was high in this treatment modality so according to our study results, low intensity pulmonary rehabilitation treatment can be prefer to high intensity pulmonary rehabilitation treatment in COPD

Effective Factors on Unassisted Smoking Cessation

Objective: This study aimed to evaluate the contribution which effective factors on who self-quitting smoking. Methods: The study had been included in over 18 years old people who not received any pharmacological treatment or psychological support. The research was performed at the 95% ±3.09 confidence interval. Age, gender, educational status, occupation, monthly income, smoking situation and effective factors on self-quitting smoking. Results: The participants had been 50.9% (509) male and 49.5 (498) female. Median age was 35 (18-87) years old; female’s median age 35 (18-83) and male’s median age 36 (18-87). From İstanbul 351 (35%), Ankara 301 (30%), Konya 207 (20%), Antalya 148 (15%) were people interviewed. This study had been the most effective factor in unassisted smoking cessation one’s own disease. The second factor had been getting fear of sick and third family pressure.The most people had been quit smoking due to diseases of respiratory system. The most fearful disease was cancer. Financial status was forth effective factor on quitting smoking. Conclusion: As a result effective factors on unassisted smoking cessation had been getting fear of sick as well as own disease. Therefore, in the process of quitting smoking, and especially young people in the project will be designed to prevent smoking was thought should be given to these issues. Also important in this regard is increasing the cigarette sales price. The compliance with laws issued to prevent smoking in closed areas, in particular young people can influence their thoughts about the hazards of smoking

Effective Factors on Unassisted Smoking Cessation

Objective: This study aimed to evaluate the contribution which effective factors on who self-quitting smoking

Factors Affecting Control and Adherence to One Year Treatment in Elderly Asthmatics in Turkey

Bu çalışma, 04-07, Mart 2016 tarihlerinde Los Angeles[Amerika Birleşik Devletleri]’da düzenlenen Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI) Kongresi‘nde bildiri olarak sunulmuştur.Amer Acad Allergy, Asthma & Immuno

Pulmonary Mr Angiography In Swyer-James Syndrome

Aim : The aim of this study was to investigate the pulmonary magnetic resonance angiography (MRA) imaging findings in Swyer - James syndrome (SJS) as a alternative imaging modalities. Methods : Thirteen patients had posteroanterior inspiratory/expira-tory chest X-ray films and pulmonary MRA with SJS (6 males, 7 females) were retrospectively studied . Gradient-echo pulmonary MRA was performed in all patients with a 1. 5 T MR unit. MRA imaging was performed in a single breath-hold during the injection of contrast media. Image analysis of the patients was performed. The results of pulmonary artery diameters and pulmonary periph-eral vasculature were compared between normal sides versus the affected sides. Statistical analysis was performed with the Student t test. Results : The smaller pulmonary artery on the affected side with poor peripheral vasculature was observed with gadolinium-en-hanced gradient-echo MRA in all patients . There was a significant difference between the diameters of the pulmonary arteries of the normal versus the disease sides (p< 0.0005). Conclusion: MRA successfully depicted the small pulmonary artery with diminished peripheral vasculature in patients with SJS. This study showed the pulmonary MRA imaging could be used as a al-ternative imaging modalities in the evaluation of patient with SJS

Asthma control and adherence in newly diagnosed young and elderly adult patients with asthma in Turkey

Objective: This study aimed to evaluate the factors that affect asthma control and adherence to treatment in newly diagnosed elderly asthmatics in Turkey compared with younger patients. Methods: This real-life prospective observational cohort study was conducted at 136 centers. A web-based questionnaire was administered to the patients who were followed up for 12 months. Results: Analysis included 1037 young adult asthma patients (age = 65 years). The percentage of patients with total control in the elderly and young groups were 33.9% and 37.1% at visit 1, 20.0% and 42.1% (p = 0.012) at visit 2, and 50.0% and 49.8% at visit 3, respectively. Adherence to treatment was similar for both groups. Visit compliance was better in the elderly group than in the young group at visit 1 (72.2% vs. 60.8%, p = 0.045), visit 2 (51.9% vs. 34.9%, p = 0.002), and visit 3 (32.9% vs. 19.4%, p = 0.004). Adherence to treatment increased with asthma control in both groups (both p < 0.001) but decreased with the presence of gastritis/ulcer, gastroesophageal reflux, and coronary artery disease in the elderly. Conclusions: Asthma control and adherence to treatment were similar for the elderly and young asthma patients, though the follow-up rate was lower in young patients. The presence of gastritis/ulcer, gastroesophageal reflux and coronary artery disease had negative impacts on the adherence to treatment in elderly adult patients