Анализ структурного состояния стыка рельса ультразвуковым методом

Статья посвящена анализу и оценке возможностей ультразвукового контроля структурного параметра материала - размера зерна в сварных стыках рельсов. Увеличение одиночного выхода рельсов из строя в процессе эксплуатации говорит об ухудшении качества производимых рельсов. Поэтому необходима разработка новых методов контроля рельсов при выпуске и оптимизации процесса производства. Существующие методы контроля структурного состояния трудоемки и требуют больших материальных затрат. Наиболее перспективными являются прецизионные методы, основанные на определении скорости ультразвуковых волн в материале. Таким образом, разработка и внедрение прецизионных акустических методов контроля качества металла рельсов, его структурного состояния является актуальной. В работе был проведен обзор современных методов структороскопии, экспериментально исследовано затухание ультразвуковых волн в основном материале и в сварных стыках рельсов

Notch signaling regulates perivascular adipose tissue (PVAT) function during diet-induced obesity

Objectives: -To test the hypothesis that canonical Notch signaling influence vascular function by regulating PVAT-derived vascular relaxation factors. -To determine how overexpression of Notch signaling or loss of the key Notch signaling component influence PVAT function.https://knowledgeconnection.mainehealth.org/lambrew-retreat-2021/1035/thumbnail.jp

ASSESSMENT OF BUSINESS ACTIVITY OF LLC «ELAN-95»

Assessment of business activity of LLC «Elan-95» for 2007-2015 is carried out. Efficiency of usage of current assets of the organization is analyzed. The analysis of indicators of business and market activity of LLC «Elan-95» is carried out. By results of the analysis conclusions and practical recommendations about improvement of efficiency of usage of means of the organization are carried out

ASSESSMENT OF BUSINESS ACTIVITY OF LLC «ELAN-95»

Assessment of business activity of LLC «Elan-95» for 2007-2015 is carried out. Efficiency of usage of current assets of the organization is analyzed. The analysis of indicators of business and market activity of LLC «Elan-95» is carried out. By results of the analysis conclusions and practical recommendations about improvement of efficiency of usage of means of the organization are carried out

Formación de la legislación sobre el seguro de pensiones en Francia, el Reino Unido y Rusia. Una retrospectiva

The relevance of the study is due to the crisis of modern pension insurance systems and the need to change the paradigm of pension legislation development. The purpose of the study is to identify the features of the formation of legislation on pension insurance in several countries (France, Great Britain, and Russia) at the initial stage of development (before 1914). The novelty is expressed both in the formulation of the problem and in the research methodology (the choice of countries and the period of research, the justification for the use of methods: dialectics, analysis, synthesis, system-structural, sociological, statistical, historical-legal, comparative-legal, formal-legal). The result of the study was the conclusions about the historical conditionality of the peculiarities of the formation of legislation on pension insurance in a particular country. There was early legalization of both voluntary and compulsory pension insurance in France. There was no legislation on pension insurance in the UK during the period under review, despite the early development of relevant institutions in the framework of workshops, guilds, and later in the framework of trade unions and “friendly societies”. In Russia, due to the agrarian nature of the economy, pension insurance did not develop within the framework of workshops and guilds; there were no laws on insurance in case of old age by 1914, while the risks of disability and loss of the breadwinner were regulated by law.El estudio analiza la crisis de los sistemas modernos pensionales y establece la necesidad de cambiar el paradigma de la legislación de pensiones. El objetivo del estudio consiste en identificar las características de la legislación sobre los seguros pensionales de varios estados (Francia, Reino Unido y Rusia) partiendo de su etapa inicial hasta 1914. La novedad se expresa tanto en la formulación del problema como en la metodología de investigación (selección de países y período de estudio, justificación de la aplicación de los métodos: dialéctico, de análisis, de síntesis, sistémico-estructural, sociológico, estadístico, histórico-legal, comparativo-legal, formal-legal). Como resultado del estudio se llegó a conclusiones sobre el condicionamiento histórico de las características de la formación de la legislación sobre el seguro de pensiones de un país en particular. En Francia, se promulgó una legislación temprana sobre el seguro de pension voluntario y también obligatorio en Francia. En el Reino Unido, durante el período que se examina, no había legislación sobre seguros de pensiones, a pesar del desarrollo temprano de las instituciones pertinentes dentro de los talleres, gremios y, posteriormente, dentro de la actividad de los sindicatos y las «sociedades fraternales». En Rusia, debido a la naturaleza agraria de la economía, el seguro de pensiones en el marco de los talleres y gremios nunca funcionó; en 1914 se adolecía de leyes sobre el seguro de vejez, mientras que los riesgos de discapacidad y la pérdida del sostén de la familia se regulaban por ley

Models of shifts and correlation links of hematological and immunological parameters of patients with chronic generalized periodontitis

The goal of this study is to examine and to evaluate hematological and immunological parameters of patients with chronic generalized periodontitis based on the models of shifts and correlations. At that, the assessment of carried-out modeling and correlations allows to identify the leading parameters of diagnostics and intrasystemic blood parameters and cell-mediated immunit

Situational modelling of oil pollution risks monitored by distributed monitoring

The work is studying the distributed system of natural environment monitoring points. The purpose of the study is to solve two main problems of optimization: a) optimization of risks of emergency events; b) optimal cessation of environmental monitoring, which allows to reduce the costs of observation. Monitoring of the environment contaminated with petroleum products is relevant. Traditionally used methods and monitoring itself are expensive and technological complex mechanisms, often requiring satellite data. When studying environmental pollution, it is important to consider situational risks and stochastic irreversible changes in nature. For this purpose, it is necessary to apply the methods and methodology of the system approach, which are used in the article for analysis of complex data structures and entropy of the system. For the informativeness of less long monitoring, it's represented by four main subsystems (capture, operation, selection and decision-making) and evaluated using an information-entropy approach. The work will solve the practical task of monitoring the contaminated environment

Cerebellar anaplastic astrocytoma in adult patients: 15 consecutive cases from a single institution and literature review

Adult cerebellar anaplastic astrocytomas (cAA) are rare entities and their clinical and genetic appearances are still ill defined. Previously, malignant gliomas of the cerebellum were combined and reviewed together (cAA and cerebellar glioblastomas (cGB), that could have possibly affected overall survival (OS) and progression-free survival (PFS). We present characteristics of 15 adult patients with cAA and compared them to a series of 45 patients with a supratentorial AA (sAA) in order to elicit the effect of tumor location on OS and PFS. The mean age at cAA diagnosis was 39.3 years (range 19–72). A history of neurofibromatosis type I was noted in 1 patient (6.7%). An IDH-1 mutation was identified in 6/15 cases and a methylated MGMT promoter in 5/15 cases. Patients in study and control groups were matched in age, sex and IDH-1 mutation status. Patients in a study group tended to present with longer overall survival (50 vs. 36.5 months), but the difference did not reach statistical significance. In both cAA and supratentorial AA groups presence of the IDH-1 mutation remains a positive predictor for the prolonged survival. The present study suggests that adult cAA constitute a group of gliomas with relatively higher rate of IDH-1 mutations and prognosis similar to supratentorial AA. The present study is the first to systematically compare cAA and supratentorial AA with respect to their genetic characteristics and suggests that both groups show a similar survival prognosis

The results of orthodontic treatment using computer design of structures

The article deals with the use of mathematical background and computer modeling in the process of treatment dental apparatus engineering. Drawing on mathematical calculations, veracity of which is validated by the results of experimental research, there in the clinic it has been used treatment appliance made of elastic polymer with set-up parameter

Effect of plant communities on aggregate composition and organic matter stabilisation in young soils

© 2014, Springer International Publishing Switzerland. Results: Deciduous forest soil accumulated the highest C content in the 0–5 cm layer (43 g C kg−1), whereas values in coniferous forest and arable soils were lower (30 and 12 g C kg−1, respectively). The highest portion of C in arable soil was accumulated in the mineral fraction (80 %), whereas 50–60 % of the C in forest soils were in POM. More C was associated with minerals in deciduous forest soil (16 g C kg−1 soil) than under coniferous forest and arable land (8–10 g C kg−1 soil). Conclusions: Particulate organic matter explains most of the differences in organic C accumulation in soils developed during 45 years under the three vegetation types on identical parent material. The C content of the mineral soil fraction was controlled by plant cover and contributed the most to differences in C accumulation in soils developed under similar vegetation type (forest). Objectives: Carbon (C) content in pools of very young soils that developed during 45 years from loess was analysed in relation to vegetation: deciduous and coniferous forests and cropland. We hypothesised that variations in the amount of particulate organic matter (POM) can explain the C accumulation and also affects the C bound to mineral surfaces in soil under various vegetation. Methods: Soil samples were collected under three vegetation types of a 45-year-old experiment focused on initial soil development. Aggregate and density fractionations were combined to analyse C accumulation in large and small macro- and microaggregates as well as in free and occluded POM and mineral factions