33,152 research outputs found
Element-specific modal formulations for large-displacement multibody dynamics
Large dispacement assumed-mode modeling techniques are examined in the context of multibody elastodynamics. The range of both general and element-specific approaches are studied with the aid of examples involving beams, plates, and shells. For systems undergoing primarily structural bending and twisting with little or no membrane distortion, it is found that fully-linear, element-specific, modal formulations provide the most accurate time history solutions at the least expense. When membrane effects become dominant in structural problems due to loading and boundary conditions, one must naturally resort to a formulation involving a nonlinear stress-strain relationship in addition to nonlinear terms associated with large overall system motion. Such nonlinear models were investigated using assumed modes and found to lead to modal convergence difficulties when standard free-free structural modes are employed. A constrained mode formulation aimed at addressing the convergence problem is proposed
Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv
Copyright: © 2010 Pink et al.Higher order chromatin folding is critical to a number of developmental processes, including the regulation of gene expression. Recently developed biochemical techniques such as RNA TRAP and chromosome conformation capture (3C) have provided us with the tools to probe chromosomal structures. These techniques have been applied to the β-globin locus, revealing a complex pattern of interactions with regions along the chromosome that the gene resides on. However, biochemical and microscopy data on the nature of β-globin interactions with other chromosomes is contradictory. Therefore we developed a novel 4C variant, Complete-genome 3C by vectorette amplification (4Cv), which allows an unbiased and quantitative method to examine chromosomal structure. We have used 4Cv to study the microenvironment of the β-globin locus in mice and show that a significant proportion of the interactions of β-globin are inter-chromosomal. Furthermore, our data show that in the liver, where the gene is active, β-globin is more likely to interact with other chromosomes, compared to the brain where the gene is silent and is more likely to interact with other regions along the same chromosome. Our data suggest that transcriptional activation of the β-globin locus leads to a change in nuclear position relative to the chromosome territory.Ryan Pink is supported by a grant from Action Medical Research; Daniel Caley is supported by a grant from The Dunhill Medical Trust; David Carter is supported by a grant from the British Society for Haematology
Hollingsworth v. Perry, Brief for Foreign and Comparative Law Experts Harold Hongju Koh et. al. as Amici Curiae Supporting Respondents
SU(3) Spin-Orbit Coupling in Systems of Ultracold Atoms
Motivated by the recent experimental success in realizing synthetic
spin-orbit coupling in ultracold atomic systems, we consider N-component atoms
coupled to a non-Abelian SU(N) gauge field. More specifically, we focus on the
case, referred to here as "SU(3) spin-orbit-coupling," where the internal
states of three-component atoms are coupled to their momenta via a matrix
structure that involves the Gell-Mann matrices (in contrast to the Pauli
matrices in conventional SU(2) spin-orbit-coupled systems). It is shown that
the SU(3) spin-orbit-coupling gives rise to qualitatively different phenomena
and in particular we find that even a homogeneous SU(3) field on a simple
square lattice enables a topologically non-trivial state to exist, while such
SU(2) systems always have trivial topology. In deriving this result, we first
establish an exact equivalence between the Hofstadter model with a 1/N Abelian
flux per plaquette and a homogeneous SU(N) non-Abelian model. The former is
known to have a topological spectrum for N>2, which is thus inherited by the
latter. It is explicitly verified by an exact calculation for N=3, where we
develop and use a new algebraic method to calculate topological indices in the
SU(3) case. Finally, we consider a strip geometry and establish the existence
of three gapless edge states -- the hallmark feature of such an SU(3)
topological insulator.Comment: 4.2 pages, 1 figur
Perancangan Interior Lobby, Café Dan Retail Stadion Futsal Di Surabaya
Design Interior for Futsal Stadium's Lobby, Café and Retail in Surabaya is based on the reality of futsal in Indonesia is the most popular sports among the society but only for playing with friends and spend the time during weekend. In fact, futsal is less exposed in terms of professional competitions and achievements of the Indonesian National Team that has a good potential by achieving to the top 10 of Asia region. With these facts, futsal should get more attentions and supports from the society, by build a Futsal Stadium. Furthermore, Futsal Stadium could possibly become city icon and attract the urban society attentions towards futsal. This design aims to support the stadium facilities in order to be able to hold the competition up to the International level and to increase the enthusiasm of the society towards futsal, because with the more support from society, we hope that it might improve the achievement of Indonesian National Team
Three path interference using nuclear magnetic resonance: a test of the consistency of Born's rule
The Born rule is at the foundation of quantum mechanics and transforms our
classical way of understanding probabilities by predicting that interference
occurs between pairs of independent paths of a single object. One consequence
of the Born rule is that three way (or three paths) quantum interference does
not exist. In order to test the consistency of the Born rule, we examine
detection probabilities in three path intereference using an ensemble of
spin-1/2 quantum registers in liquid state nuclear magnetic resonance (LSNMR).
As a measure of the consistency, we evaluate the ratio of three way
interference to two way interference. Our experiment bounded the ratio to the
order of , and hence it is consistent with Born's rule.Comment: 11 pages, 4 figures; Improved presentation of figures 1 and 4,
changes made in section 2 to better describe the experiment, minor changes
throughout, and added several reference
"GiGa": the Billion Galaxy HI Survey -- Tracing Galaxy Assembly from Reionization to the Present
In this paper, we review the Billion Galaxy Survey that will be carried out
at radio--optical wavelengths to micro--nanoJansky levels with the telescopes
of the next decades. These are the Low-Frequency Array, the Square Kilometer
Array and the Large Synoptic Survey Telescope as survey telescopes, and the
Thirty Meter class Telescopes for high spectral resolution+AO, and the James
Webb Space Telescope (JWST) for high spatial resolution near--mid IR follow-up.
With these facilities, we will be addressing fundamental questions like how
galaxies assemble with super-massive black-holes inside from the epoch of First
Light until the present, how these objects started and finished the
reionization of the universe, and how the processes of star-formation, stellar
evolution, and metal enrichment of the IGM proceeded over cosmic time. We also
summarize the high-resolution science that has been done thus far on high
redshift galaxies with the Hubble Space Telescope (HST). Faint galaxies have
steadily decreasing sizes at fainter fluxes and higher redshifts, reflecting
the hierarchical formation of galaxies over cosmic time. HST has imaged this
process in great structural detail to z<~6. We show that ultradeep
radio-optical surveys may slowly approach the natural confusion limit, where
objects start to unavoidably overlap because of their own sizes, which only SKA
can remedy with HI redshifts for individual sub-clumps. Finally, we summarize
how the 6.5 meter James Webb Space Telescope (JWST) will measure first light,
reionization, and galaxy assembly in the near--mid-IR.Comment: 8 pages, LaTeX2e requires 'aip' style (included), 8 postscript
figures. To appear in the proceedings of the `The Evolution of Galaxies
through the Neutral Hydrogen Window' conference, Arecibo Observatory Feb 1-3,
2008; Eds. R. Minchin & E. Momjian, AIP Conf Pro
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