Long Duration Life Test of Propylene Glycol Water Based Thermal Fluid Within Thermal Control Loop

Evaluations of thermal properties and resistance to microbial growth concluded that 50% Propylene Glycol (PG)-based fluid and 50% de-ionized water mixture was desirable for use as a fluid within a vehicle s thermal control loop. However, previous testing with a commercial mixture of PG and water containing phosphate corrosion inhibitors resulted in corrosion of aluminum within the test system and instability of the test fluid. This paper describes a follow-on long duration testing and analysis of 50% Propylene Glycol (PG)-based fluid and 50% de-ionized water mixture with inorganic corrosion inhibitors used in place of phosphates. The test evaluates the long-term fluid stability and resistance to microbial and chemical change

A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters

Dynamic exchange of a subset of nucleosomes in vivo plays important roles in epigenetic inheritance of chromatin states, chromatin insulator function, chromosome folding, and the maintenance of the pluripotent state of embryonic stem cells. Here, we extend a pulse-chase strategy for carrying out genome-wide measurements of histone dynamics to several histone variants in murine embryonic stem cells and somatic tissues, recapitulating expected characteristics of the well characterized H3.3 histone variant. We extended this system to the less-studied MacroH2A2 variant, commonly described as a repressive histone variant whose accumulation in chromatin is thought to fix the epigenetic state of differentiated cells. Unexpectedly, we found that while large intergenic blocks of MacroH2A2 were stably associated with the genome, promoter-associated peaks of MacroH2A2 exhibited relatively rapid exchange dynamics in ES cells, particularly at highly-transcribed genes. Upon differentiation to embryonic fibroblasts, MacroH2A2 was gained primarily in additional long, stably associated blocks across gene-poor regions, while overall turnover at promoters was greatly dampened. Our results reveal unanticipated dynamic behavior of the MacroH2A2 variant in pluripotent cells, and provide a resource for future studies of tissue-specific histone dynamics in vivo

Mulan: An Exploration of Culture and Representation in Hollywood

\u27Mulan: An Exploration of Culture and Representation in Hollywood\u27 is a presentation and detailed analysis of various representational, cultural, and minority-related issues in the context of Hollywood and western media. The presentation will focalize specifically around the recent live-action remake of the 1998 film Mulan . The remake, premiered in March 2020, received critical backlash from various audiences (mostly from the BIPOC community), bashing the film for its misrepresentation of Ancient China and Ancient Chinese culture. Through this misrepresentation, the Hollywood film ultimately reflects views of cultural appropriation, misogyny, and overall minority underrepresentation in the United States. The research presents the backlash that lead actress Liu Yifei received over the course of the film\u27s wave of criticism. Many uneducated and uninformed viewers raced to Twitter to attack her performance and \u27cooperation\u27 with this controversial film, however it is important to consider the relationship between Chinese Americans and the CCP (Chinese Communist Party), as it is incredibly risky to speak out against the CCP due to the possibility of being blacklisted by the Chinese market. Overall, the presentation encompasses and analyzes the issues stirred by Mulan 2020, the response of the BIPOC community, and how the controversy is ultimately a representation of Hollywood media when dealing with portrayal of foreign cultures

Development of a hydrate-gas-water static equilibrium model and analysis of three-phase stability

Recent evidence suggests that a three-phase stability zone exists at the base of gas hydrate stability (BGHS), where hydrate and gas may coexist due to the pore size distribution. We develop a three-phase stability zone model at static equilibrium based on the idea of minimizing interfacial energy. We use this model to produce three-phase saturations and study the effects of three-phase stability for two applications. The first application is related to the migration of gas from beneath sealing hydrate layers to the seafloor. A proposed mechanism for this upwards gas migration is the generation of fractures through the sealing hydrate sediment due to overpressures caused by the accumulation of gas on geologic timescales. Our study focuses on how the fracturing potential of a three-phase stability zone differs from a discrete BGHS, where hydrate is separated from gas by a sharp boundary. We model gas overpressures at Blake Ridge, Hydrate Ridge, and the Kumano Basin by incorporating mercury intrusion capillary pressure data with our three-phase stability model. Our results show that the overpressures in the three-phase stability model are smaller, reducing the potential for gas-driven fracturing. We also find that hydrate-bearing basins with shallower seafloor depths modeled with three-phase stability need much more methane to generate the overpressures that will initiate fractures. The second application of three-phase stability relates to the bottom-simulating reflection (BSR), which is a common negative polarity reflection in marine sediments that often follows the contour of the seafloor. Recent literature suggests that the BSR indicates the shallowest presence of gas, not the BGHS. This three-phase stability model has an impact on the seismic response of the BSR, and we study this effect by developing 1-D rock physics models of Blake Ridge. By varying the methane quantity and performing fluid substitution with three-phase saturation profiles, we generate synthetic seismograms and analyze the difference in two way travel time (TWTT). For comparison, we use the workflow for a parameter sensitivity model and an original-resolution model. Through this analysis, we find a relationship between the TWTT width of the BSR’s peaks and the methane abundance at the BGHSPetroleum and Geosystems Engineerin

"Change for the better: The impact of Team Wise Proactive Change Management on burnout and team outcomes"

Past research on proactivity has focused on the frequency of proactive behaviours of individuals rather than the content of such behaviours and its operationalisation within teams. It is no longer sufficient to be merely proactive when dealing with ongoing changes within organisations or working when working in teams. My thesis introduces team wise proactive change management (TWPCM), where teams proactively manage change in ways that consider the situational, relational, and their own resources in addressing future challenges and reaching their goals. This paper examines the impact of TWPCM on burnout and the flow-on effects to team withdrawal and performance outcomes within the healthcare sector. To examine this, I propose three research questions: Does TWPCM alleviate burnout within healthcare teams?, Does the effect of TWPCM on burnout flow onto withdrawal and performance outcomes within the teams?, and Do work demands inhibit the positive benefits of TWPCM and its effects on burnout, withdrawal and performance outcomes within healthcare teams?. I employed a quantitative research design and drew on team aggregated survey data from a local health district in NSW, comprising 2324 nurses and midwives across 196 teams,. I also linked this survey data in terms of participants’ perception work to objective archival data across 12 months post survey completion, including patient safety data – specifically the number of medication and IV-related errors, as well as human resources data on leave and turnover. Findings show that TWPCM was indirectly negatively associated with undesirable team outcomes (team turnover, absenteeism and medication and IV errors) via burnout. Further, work demands moderated these indirect effects, whereby the relationship was weaker (creating barriers to alleviating undesirable consequences) when work demands are high. Importantly, the results indicate that wise proactive behaviours have theoretical and practical implications on healthcare workers and hospitals, and future researchers. My findings shed light on to the important role of wise proactive change management for teams and advances the empirical evidence and knowledge on how to effectively manage change to benefit not just organisations but also employees and the society

Creating Dementia-Friendly and Inclusive Communities for Social Inclusion: A Scoping Review Protocol

Introduction The number of people with dementia is increasing worldwide, with the majority of people with dementia living at home in the community. WHO calls for global action on the public health response to dementia. Social exclusion is commonly reported by people with dementia and their families. Dementia-friendly and inclusive community has emerged as an idea that holds potential to contribute to the mitigation of social exclusion. The objective of the scoping review is to answer two questions: What social inclusion strategies that have been reported in the dementia-friendly and inclusive communities’ literature? What strategies for developing dementia-friendly and inclusive communities that have shown to improve social inclusion? Methods and analysis This scoping review will follow the Joanna Briggs Institute scoping review methodology and will take place between April and September 2020. The proposed review will consider studies based in community settings with participants living at home with early to late stages of dementia and their families. This includes a three-step search strategy: (1) to identify keywords from MEDLINE and CINAHL; (2) to conduct a second search using all identified keywords and index terms across selected databases (MEDLINE, CINAHL, AgeLine, PsycINFO, Web of Science, ProQuest and Google) and (3) to handsearch the reference lists of all included articles and reports for additional studies. Further, we will search Google for grey literature on published organisational reports. Two researchers will screen titles and abstracts independently and then assess the full text of selected citations against inclusion criteria. Extracted data will be presented in a narrative accompanied by tables that reflect the objective of the review

Quantum rotor theory of spinor condensates in tight traps

In this work, we theoretically construct exact mappings of many-particle bosonic systems onto quantum rotor models. In particular, we analyze the rotor representation of spinor Bose-Einstein condensates. In a previous work it was shown that there is an exact mapping of a spin-one condensate of fixed particle number with quadratic Zeeman interaction onto a quantum rotor model. Since the rotor model has an unbounded spectrum from above, it has many more eigenstates than the original bosonic model. Here we show that for each subset of states with fixed spin F_z, the physical rotor eigenstates are always those with lowest energy. We classify three distinct physical limits of the rotor model: the Rabi, Josephson, and Fock regimes. The last regime corresponds to a fragmented condensate and is thus not captured by the Bogoliubov theory. We next consider the semiclassical limit of the rotor problem and make connections with the quantum wave functions through use of the Husimi distribution function. Finally, we describe how to extend the analysis to higher-spin systems and derive a rotor model for the spin-two condensate. Theoretical details of the rotor mapping are also provided here.Comment: 10 pages, 2 figure