745 research outputs found

    PENERAPAN PENDIDIKAN KARAKTER DALAM MEMBENTUK KEPRIBADIAN ANAK PADA PAUD USIA 4-6 TAHUN DI UPTD SKB PACITAN

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    Penelitian ini bertujuan untuk mendeskripsikan dan menganalisa penerapan pendidikan karakter di PAUD Putra Agung Pacitan. Yakni, untuk mengetahui strategi penerapan pendidikan karakter dalam membentuk kepribadian anak pada PAUD usia 4-6 tahun di UPTD SKB Pacitan , Kemudian untuk mendeskripsikan kepribadian anak PAUD usia 4- 6 tahun terhadap pendidikan karakter di UPTD SKB Pacitan, Untuk menguraikan faktor penghambat dalam penerapan pendidikan karakter guna membentuk kepribadian anak di UPTD SKB Pacitan. Serta untuk menjabarkan faktor pendudukung dalam penerapan pendidikan karakter untuk membentuk kepribadian anak di UPTD SKB Pacitan.   Penelitian ini menggunakan pendekatan deskriptif kualitatif. Subjek dalam penelitian ini adalah kepala SKB, tutor dan peserta didik di PAUD Putra Agung Pacitan. Data dikumpulkan melalui metode observasi, wawancara, dan dokumentasi. Data yang terkumpul dianalisis menggunakan model analisis interaktif. . Kredibilitas dengan kriteria ini data dan informasi yang dikumpulkan harus mengandung nilai kebenaran, yang berarti bahwa hasil penelitian kualitatif harus dapat  di percaya. Dependabilitas adalah kriteria untuk penelitian kualitatif apakah proses penelitian bermutu atau tidak. Konfimabilitas ada kemiripan dengan kriteria dendibilitas, hanya saja kriteria yang menilai kualitas hasil penelitian dengan penulusuaran dan pelacakan catatan/rekaman data lapangan dan koherensinya dalam interpretasi dan simpulan. Transferabilitas hasil penelitian dapat ditransfer atau tidak merupakan pernyataan empiris yang tidak dapat dijawab oleh peneliti kualitatif itu sendiri.   Pendidikan karakter di PAUD Putra Agung sudah berjalan dengan baik dimana proses penerapananya dilaksanakan melalui proses perencanaan, pelaksanaan dan evaluasi. Kepribadian anak sehubungan dengan hasil penerapan pendidikan karakter di PAUD Putra Agung memperlihatkan bahwa kepribadian serta perilaku peserta didik telah mencerminkan kepribadian yang berkarakter. Faktor penghambat yaitu karakteristik dari masing-masing peserta didik yang berbeda-beda, pendanaan masih dibebankan pada pihak sekolah, serta minimnya evaluasi. Faktor pendukung yaitu adanya muatan pendidikan karakter dalam kurikulum sekolah,  kemudian  ada motivasi  dari sekolah, dan sarana beserta prasarana yang menunjang untuk penerapan pendidikan karakter sudah memadai.   Kata Kunci: Pendidikan Anak Usia Dini, Pedidikan Karakter, Kepribadia

    Preparation of GP5-M Heterodimer Glycantype Specific Recombinant Protein and Replicon Particles

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    Porcine Reproductive and Respiratory Syndrome (PRRS) imposes a huge financial burden on the swine industry. Thus, there is a clear and immediate need for improved PRRS virus (PRRSV) vaccines. Our group has proposed a new classification scheme for PRRSV strains that allows for immunological differentiation based on level of GP5 glycosylation. This classification based on glycantype has allowed us to choose PRRSV strains that offer the best chance of protection against PRRS

    Immunization for Influenza A Virus by Intranasal Administration of Alphavirus Replicon Particles

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    Improved vaccines are necessary to prevent swine influenza, especially in young growing pigs. The objective of this study is to determine whether intranasal vaccination with Alphavirus replicon particle (RP) vector vaccine prevents influenza A virus (IAV) in pigs. RP vaccine was prepared with the hemagglutinin (HA) gene of pandemic H1N1 influenza virus (A/California/04/2009, pH1N1). The efficacy of intranasal (IN) administration with pH1N1 HA RP was evaluated in two pig experiments. In the first experiment, prime/boost RP vaccination was administered IN/IN to pigs. In the second experiment, pigs were administered a one dose intramuscular (IM) or IN HA RP vaccine, or with a combination of IN/IM routes with an interval of three weeks. Results showed that two doses IN administration of HA RP did not protect pigs against IAV; one dose IM and combination IN/IM routes vaccination with HA RP reduced pneumonia significantly and partially inhibited virus shedding following homologous challenge

    Rapid Development of Efficacious Swine Vaccines for Pandemic H1N1

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    Pandemic H1N1 (pH1N1) influenza was first reported in the United States in April 2009. Since then, the virus has spread worldwide in both human and swine populations. Currently, pH1N1 influenza is the most common H1N1 virus infecting pigs in the United States. Vaccination of swine against pH1N1 represents the single best method of protecting against infection

    Replicon Particle Administration Prior to Challenge Reduces PRRSV Viremia

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    Vaccination of swine with an alphavirus-derived replicon particle vaccine stimulates a non-specific immune response. This effect was seen when animals were challenged with PRRSV at 24 hours post-vaccination. Animals that received vaccine had reduced viremia as measured by quantitative RT-PCR when compared to placebo. These results highlight the potential of replicon particle vaccines to induce robust immune responses in swine

    Rational synthesis of novel biocompatible thermoresponsive block copolymer worm gels

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    It is well known that reversible addition–fragmentation chain transfer (RAFT) aqueous dispersion polymerization of 2-hydroxypropyl methacrylate (HPMA) enables the rational design of diblock copolymer worm gels. Moreover, such hydrogels can undergo degelation on cooling below ambient temperature as a result of a worm-to-sphere transition. However, only a subset of such block copolymer worms exhibit thermoresponsive behavior. For example, PMPC26–PHPMA280 worm gels prepared using a poly(2-(methacryloyloxy)ethyl phosphorylcholine) (PMPC26) precursor do not undergo degelation on cooling to 6 °C (see S. Sugihara et al., J. Am. Chem. Soc., 2011, 133, 15707–15713). Informed by our recent studies (N. J. Warren et al., Macromolecules, 2018, 51, 8357–8371), we decided to reduce the mean degrees of polymerization of both the PMPC steric stabilizer block and the structure-directing PHPMA block when targeting a pure worm morphology. This rational approach reduces the hydrophobic character of the PHPMA block and hence introduces the desired thermoresponsive character, as evidenced by the worm-to-sphere transition (and concomitant degelation) that occurs on cooling a PMPC15–PHPMA150 worm gel from 40 °C to 6 °C. Moreover, worms are reconstituted on returning to 40 °C and the original gel modulus is restored. This augurs well for potential biomedical applications, which will be examined in due course. Finally, small-angle X-ray scattering studies indicated a scaling law exponent of 0.67 (≈2/3) for the relationship between the worm core cross-sectional diameter and the PHPMA DP for a series of PHPMA-based worms prepared using a range of steric stabilizer blocks, which is consistent with the strong segregation regime for such systems

    "Ordinary, the same as anywhere else": notes on the management of spoiled identity in 'marginal' middle class neighbourhoods

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    Urban sociologists are becoming increasingly interested in neighbourhood as a source of middle-class identity. Particular emphasis is currently being given to two types of middle-class neighbourhood; gentrified urban neighbourhoods of ‘distinction’ and inconspicuous ‘suburban landscapes of privilege’. However, there has been a dearth of work on ‘marginal’ middle-class neighbourhoods that are similarly ‘inconspicuous’ rather than distinctive, but less exclusive, thus containing sources of ‘spoiled identity’. This article draws on data gathered from two ‘marginal’ middleclass neighbourhoods that contained a particular source of ‘spoiled identity’: social renters. Urban sociological analyses of neighbour responses to these situations highlight a process of dis-identification with the maligned object, which exacerbates neighbour differences. Our analysis of data from the ‘marginal’ middle-class neighbourhoods suggests something entirely different and Goffmanesque. This entailed the management of spoiled identity, which emphasized similarities rather than differences between neighbours.</p

    Hydrocarbon-based statistical copolymers outperform block copolymers for stabilization of ethanol–water Foams

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    Well-defined block copolymers have been widely used as emulsifiers, stabilizers, and dispersants in the chemical industry for at least 50 years. In contrast, nature employs amphiphilic proteins as polymeric surfactants whereby the spatial distribution of hydrophilic and hydrophobic amino acids within the polypeptide chains is optimized for surface activity. Herein, we report that polydisperse statistical copolymers prepared by conventional free-radical copolymerization can provide superior foaming performance compared to the analogous diblock copolymers. A series of predominantly (meth)acrylic comonomers are screened to identify optimal surface activity for foam stabilization of aqueous ethanol solutions. In particular, all-acrylic statistical copolymers comprising trimethylhexyl acrylate and poly(ethylene glycol) acrylate, P(TMHA-stat-PEGA), confer strong foamability and also lower the surface tension of a range of ethanol–water mixtures to a greater extent than the analogous block copolymers. For ethanol-rich hand sanitizer formulations, foam stabilization is normally achieved using environmentally persistent silicone-based copolymers or fluorinated surfactants. Herein, the best-performing fully hydrocarbon-based copolymer surfactants effectively stabilize ethanol-rich foams by a mechanism that resembles that of naturally-occurring proteins. This ability to reduce the surface tension of low-surface-energy liquids suggests a wide range of potential commercial applications

    Generation of Bianchi type V cosmological models with varying Λ\Lambda-term

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    Bianchi type V perfect fluid cosmological models are investigated with cosmological term Λ\Lambda varying with time. Using a generation technique (Camci {\it et al.}, 2001), it is shown that the Einstein's field equations are solvable for any arbitrary cosmic scale function. Solutions for particular forms of cosmic scale functions are also obtained. The cosmological constant is found to be decreasing function of time, which is supported by results from recent type Ia supernovae observations. Some physical aspects of the models are also discussed.Comment: 16 pages, 3 figures, submitted to CJ

    An Extreme Solar Event of 20 January 2005: Properties of the Flare and the Origin of Energetic Particles

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    The extreme solar and SEP event of 20 January 2005 is analyzed from two perspectives. Firstly, we study features of the main phase of the flare, when the strongest emissions from microwaves up to 200 MeV gamma-rays were observed. Secondly, we relate our results to a long-standing controversy on the origin of SEPs arriving at Earth, i.e., acceleration in flares, or shocks ahead of CMEs. All emissions from microwaves up to 2.22 MeV line gamma-rays during the main flare phase originated within a compact structure located just above sunspot umbrae. A huge radio burst with a frequency maximum at 30 GHz was observed, indicating the presence of a large number of energetic electrons in strong magnetic fields. Thus, protons and electrons responsible for flare emissions during its main phase were accelerated within the magnetic field of the active region. The leading, impulsive parts of the GLE, and highest-energy gamma-rays identified with pi^0-decay emission, are similar and correspond in time. The origin of the pi^0-decay gamma-rays is argued to be the same as that of lower energy emissions. We estimate the sky-plane speed of the CME to be 2000-2600 km/s, i.e., high, but of the same order as preceding non-GLE-related CMEs from the same active region. Hence, the flare itself rather than the CME appears to determine the extreme nature of this event. We conclude that the acceleration, at least, to sub-relativistic energies, of electrons and protons, responsible for both the flare emissions and the leading spike of SEP/GLE by 07 UT, are likely to have occurred simultaneously within the flare region. We do not rule out a probable contribution from particles accelerated in the CME-driven shock for the leading GLE spike, which seemed to dominate later on.Comment: 34 pages, 14 Postscript figures. Solar Physics, accepted. A typo corrected. The original publication is available at http://www.springerlink.co
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