Links Between Social Support, Thwarted Belongingness, and Suicide Ideation among Lesbian, Gay, and Bisexual College Students

Emerging adults with a lesbian, gay, or bisexual (LGB) identity are at greater risk for engaging in suicide-related behaviors. This disparity highlights a need to elucidate specific risk and protective factors associated with suicide-related behaviors among LGB youth, which could be utilized as targets for suicide prevention efforts in this population. Informed by the interpersonal-psychological theory of suicide, the present study hypothesized that social support would be indirectly associated with decreased suicide ideation via lower thwarted belongingness. A sample of 50 emerging adults (62.0% male, 70.0% Hispanic) who identified as gay, lesbian, bisexual, questioning, or “other” orientation, with a mean age of 20.84 years (SD = 3.30 years), completed self-report assessments. Results indicated that support from both family and the LGB community were associated with lower thwarted belongingness over and above the effects of age, sex, and depressive symptoms. Indirect effects models also indicated that both family and LGB community support were associated with suicide ideation via thwarted belongingness. The results of the present study suggest that family and LGB community support may represent specific targets for reducing thwarted belongingness that could be leveraged in suicide prevention efforts for LGB emerging adults

2014 Dahlberg Award Winner: The effects of dietary toughness on occlusopalatal variation in savanna baboons

This study investigates the relationship between dietary toughness and craniofacial variation in two groups of savanna baboons. Standard craniofacial and malocclusion data were collected from a captive, soft-diet experiment group (n=24) and a sample of wild-captured baboons, raised on tougher, natural foods (n=19). We tested the hypothesis that in the absence of normal masticatory stress experienced during the consumption of wild foods, the captive baboons would exhibit higher levels of facial and dental structural irregularities. Principal component analysis indicates separation of the two samples. The soft-diet sample exhibits significantly shorter palates, greater variability in palate position, and higher frequencies of occlusal irregularities that correlate with the shorter palates. Results offer further support that long-term dietary chewing stresses have a measurable effect on adult craniofacial variation

Costs Associated with Recurrent Epistaxis in a Patient with a Ventricular Assist Device

Mucosal bleeding is a well-known complication of having a ventricular assist device and commonly presents with epistaxis. Although the frequency of epistaxis as a complication in patients with a ventricular assist device has been documented in the literature, to our knowledge the cost of this complication has not been reported. This case report examines the financial burden of ventricular assist device-associated epistaxis in a single patient from September 2018 to December 2019 using ICD 10 diagnostic codes. The patient was found to have accumulated $138,020 in costs over 38 encounters. This case report not only highlights the recurrent nature and potential high cost of epistaxis in this patient population, but also identifies a target to reduce healthcare spending. Further research is needed to assess whether cheap and simple preventative measures such as nasal hygiene regimen can decrease the frequency and/or severity of epistaxis in the patients with a ventricular assist device

Systematic performance of the ASKAP Fast Radio Burst search algorithm

Detecting fast radio bursts (FRBs) requires software pipelines to search for dispersed single pulses of emission in radio telescope data. In order to enable an unbiased estimation of the underlying FRB population, it is important to understand the algorithm efficiency with respect to the search parameter space and thus the survey completeness. The Fast Real-time Engine for Dedispersing Amplitudes (FREDDA) search pipeline is a single pulse detection pipeline designed to identify radio pulses over a large range of dispersion measures (DM) with low latency. It is used on the Australian Square Kilometre Array Pathfinder (ASKAP) for the Commensal Real-time ASKAP Fast Transients (CRAFT) project . We utilise simulated single pulses in the low- and high-frequency observation bands of ASKAP to analyse the performance of the pipeline and infer the underlying FRB population. The simulation explores the Signal-to-Noise Ratio (S/N) recovery as a function of DM and the temporal duration of FRB pulses in comparison to injected values. The effects of intra-channel broadening caused by dispersion are also carefully studied in this work using control datasets. Our results show that for Gaussian-like single pulses, $> 85 \%$ of the injected signal is recovered by pipelines such as FREDDA at DM < 3000 $\mathrm{pc\ cm^{-3}}$ using standard boxcar filters compared to an ideal incoherent dedispersion match filter. Further calculations with sensitivity implies at least $\sim 10\%$ of FRBs in a Euclidean universe at target sensitivity will be missed by FREDDA and HEIMDALL, another common pipeline, in ideal radio environments at 1.1 GHz.Comment: 11 pages 13 figures. Accepted for MNRAS; Data and simulation code available onlin

Asymptotic Relaxation of Moment Equations for a Multi-Species, Homogeneous BGK Model

Multi-species BGK models describe the dynamics of rarefied gases with constituent particles of different elements or compounds with potentially non-trivial velocity distributions. In this paper, moment equations for the bulk velocities, energies, and temperatures of a spatially homogeneous multi-species BGK model are examined. A key challenge in analyzing these equations is the fact that the collision frequencies are allowed to depend on the species temperatures, which allows for more realistic simulations of dilute gas flow. Therefore, a positive lower bound is established for the species temperatures. With this lower bound, a global existence and uniqueness of solutions to the coupled velocity-energy ODE system is established. The lower bound also enables a proof of exponential decay to a unique steady-state solution. Numerical results are presented to demonstrate how the bulk velocities and temperatures relax for large times.Comment: 21 pages, 3 figure

Prospective Phase II trial of drug-eluting bead chemoembolization for liver transplant candidates with hepatocellular carcinoma and marginal hepatic reserve.

Purpose: To determine whether chemoembolization using drug-eluting beads (DEB-TACE) is safe and effective for liver transplantation candidates with liver-limited hepatocellular carcinoma (HCC) without vascular invasion and baseline hepatic dysfunction. Materials and methods: Seventeen adult liver transplantation candidates (median age 66 years, range 58-73 years; 13 men) with HCC were treated with DEB-TACE as a part of Stage 1 of a prospective single-institution Phase II trial. All patients had marginal hepatic reserve based on at least one of the following criteria: ascites (n=14), bilirubin between 3 and 6 mg/dL (n=5), AST 5-10 times upper normal limit (n=1), INR between 1.6 and 2.5 (n=4), portal vein thrombosis (n=2), and/or portosystemic shunt (n=2). Primary study objectives were safety and best observed radiographic response. Results: Thirty-seven DEB-TACE procedures were performed. Objective response rate and disease control rate were 63% and 88%, respectively. HCC progression was observed in 12 patients. Median time to progression was 5.6 months (range 0.9-13.6 months). Within 1 month following DEB-TACE, 13 patients (76%) developed grade 3 or 4 AE attributable to the procedure. Four patients (all within Milan Criteria) were transplanted (2.7-6.9 months after DEB-TACE), and 12 patients died (1.8-32 months after DEB-TACE). All deaths were due to liver failure that was either unrelated to HCC (n=5), in the setting of metastatic HCC (n=5), or in the setting of locally advanced HCC (n=2). Mortality rate at 1 month was 0%. Conclusions: DEB-TACE achieves tumor responses but carries a high risk of hepatotoxicity for liver transplant candidates with HCC and marginal hepatic reserve