Perceptual organization and visual awareness: the case of amodal completion

We investigated the involvement of visual awareness in amodal completion, and specifically, whether visual awareness plays a differential role in local versus global completion, using a primed shape discrimination paradigm and the color-opponent flicker technique to render the prime invisible. In four experiments, participants discriminated the shape of a target preceded by a partly occluded or a neutral prime. All primes were divergent occlusion patterns in which the local completion is based on good continuation of the contours at the point of occlusion and the global completion is based on maximum symmetry. The target corresponded to the shape that could arise as a result of local or global completion of the occluded prime. For each experiment with an invisible prime we conducted a version with a visible prime. Our results suggest that local completion, but not global completion, of a partly occluded shape can take place in the absence of visual awareness, but apparently only when the visible occluded shape generates a single, local completion. No completion, either local or global, appears to take place in the absence of visual awareness when the visible occluded shape generates multiple completions. The implications of these results to the differential role of visual awareness in local and global completions and to the relationship between multiple completions and unconscious amodal completions are discussed

SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues

Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component. Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci (eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene), including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types

A first update on mapping the human genetic architecture of COVID-19

peer reviewe

The competition between grouping cues can be resolved under inattention_sup

supplementary - individual means and RT delta plots for Rashal & Kimchi (AP&P

What does visual agnosia tell us about perceptual organization and its relationship to object perception

The authors studied 2 patients, S.M. and R.N., to examine perceptual organization and its relationship to object recognition. Both patients had normal, low-level vision and performed simple grouping operations normally but were unable to apprehend a multielement stimulus as a whole. R.N. failed to derive global structure even under optimal stimulus conditions, was less sensitive to grouping by closure, and was more impaired in object recognition than S.M. These findings suggest that perceptual organization involves a multiplicity of processes, some of which are simpler and are instantiated in lower order areas of visual cortex (e.g., collinearity). Other processes are more complex and rely on higher order visual areas (e.g., closure and shape formation). The failure to exploit these latter configural processes adversely affects object recognition. The consciously perceived visual world is very different from the raw visual information or retinal mosaic of intensities and colors that arises from external objects. From the chaotic juxtaposition of different colors and shapes that stimulate the individual retinal receptors, an object is seen as detached and separable from adjacent objects and surfaces. This segmentation occurs despite th

What Does Visual Agnosia Tell Us About Perceptual Organization and Its Relationship to Object Perception?

The authors studied 2 patients, S.M. and R.N., to examine perceptual organization and its relationship to object recognition. Both patients had normal, low-level vision and performed simple grouping operations normally but were unable to apprehend a multielement stimulus as a hole. R.N. failed to derive global structure even under optimal stimulus conditions, was less sensitive to grouping by closure, and was more impaired in object recognition than S.M. These findings suggest that perceptual organization involves a multiplicity of processes, some of which are simpler and are instantiated in lower order areas of visual cortex (e.g., collinearity). Other processes are more complex and rely on higher order visual areas (e.g., closure and shape formation). The failure to exploit these latter configural processes adversely affects object recognition

What Does Visual Agnosia Tell Us About Perceptual Organization and Its Relationship to Object Perception?

The authors studied 2 patients, S.M. and R.N., to examine perceptual organization and its relationship to object recognition. Both patients had normal, low-level vision and performed simple grouping operations normally but were unable to apprehend a multielement stimulus as a whole. R.N. failed to derive global structure even under optimal stimulus conditions, was less sensitive to grouping by closure, and was more impaired in object recognition than S.M. These findings suggest that perceptual organization involves a multiplicity of processes, some of which are simpler and are instantiated in lower order areas of visual cortex (e.g., collinearity). Other processes are more complex and rely on higher order visual areas (e.g., closure and shape formation). The failure to exploit these latter configural processes adversely affects object recognition