748 research outputs found

    Interview with Ruth Jacobs

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    Discusses husband\u27s notebook, Orville Wright, wind tunnels, restoration of Wright plane, poor US reception, Kettering, Deeds, Orville\u27s car, Brewer, Smithsonian, Langley, G. Curtiss, and Paul L. Dunbar

    The early expansion and evolutionary dynamics of POU class genes.

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    The POU genes represent a diverse class of animal-specific transcription factors that play important roles in neurogenesis, pluripotency, and cell-type specification. Although previous attempts have been made to reconstruct the evolution of the POU class, these studies have been limited by a small number of representative taxa, and a lack of sequences from basally branching organisms. In this study, we performed comparative analyses on available genomes and sequences recovered through "gene fishing" to better resolve the topology of the POU gene tree. We then used ancestral state reconstruction to map the most likely changes in amino acid evolution for the conserved domains. Our work suggests that four of the six POU families evolved before the last common ancestor of living animals-doubling previous estimates-and were followed by extensive clade-specific gene loss. Amino acid changes are distributed unequally across the gene tree, consistent with a neofunctionalization model of protein evolution. We consider our results in the context of early animal evolution, and the role of POU5 genes in maintaining stem cell pluripotency

    Remembering as a Source of Creation in the Poetry of Ezra Pound and H.D. and the Musical Representations of the Holocaust by Arnold Schoenberg and Steve Reich

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    This project explores the complex relationship between language and violence. Many theorists, such as Elaine Scarry, argue that language is silenced by violence and that extreme trauma inherently defies representation. Despite the impossibility of representing trauma, its preservation is a cultural and historical necessity. I am going to examine the different ways extreme violence is depicted in both poetry and music and the complex moral issues that are raised by these representations. Ezra Pound wrote The Pisan Cantos while imprisoned in a cage at the DTC in Pisa. I plan on exploring the role of personal and cultural memory in the Pisan Cantos as well as his depictions of WWII and in particular, the way he aligns the current war with ancient history. H.D.’s Triology explores similar questions and her personal experiences in WWI caused her to evaluate very directly, the role of writing and preservation in the face of destruction. I am also planning on comparing these works with the way the Holocaust is represented in Steve Reich’s Different Trains and Shoenberg’s A Survivor from Warsaw, focusing on questions of authenticity and the limitation of traumatic memory

    What\u27s a Mother to Do?

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    A second grade arithmetic experience unit with systematic practices and tests

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    Thesis (Ed.M.)--Boston Universit

    Abstraction, ambiguity and memory in selected artworks by Ursula von Rydingsvard and Kemang wa Lehulere

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    A research report submitted to the Faculty of Humanities, University of the Witwatersrand, in partial fulfilment of the requirements for MA by Coursework and Research Report, Johannesburg, 2017This research report explores the influences of memory in selected works by two visual artists: South African Kemang Wa Lehulere’s Remembering the Future of a Hole as a Verb 2.1 and Polish artist Ursula von Rydingsvard’s Droga. The report examines the ways in which personal memory can inform creative practice and the surface difficulties such endeavours may present. These works and writings on memory and creative practice inform my own practice, through which I investigate ways of expressing my memories of my grandparents’ carpentry workshop in Sunnydale Eshowe in KwaZulu Natal, South Africa.XL201

    Pregnancy outcome following prenatal diagnosis of chromosomal anomaly: a record linkage study of 26,261 pregnancies

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    Previous studies have demonstrated the influence of changes in the age at which women give birth, and of developments in prenatal screening and diagnosis on the number of pregnancies diagnosed and terminated with chromosomal anomalies. However, we are unaware of any population studies examining pregnancy terminations after diagnosis of chromosomal anomalies that has included all aneuploidies and the influence of maternal factors. The aims of this study were to examine the association between results of prenatal tests and pregnancy termination, and the proportion of foetuses with and without chromosomal anomalies referred for invasive diagnostic tests over time. Diagnostic information of 26,261 prenatal invasive tests from all genetic service laboratories in Scotland from 2000 to 2011 was linked to Scottish Morbidity Records to obtain details on pregnancy outcome. Binary logistic regression was carried out to test the associations of year and type of diagnosis with pregnancy termination, while controlling for maternal age, neighbourhood deprivation and parity. There were 24,155 (92.0%) with no chromosomal anomalies, 1,483 (5.6%) aneuploidy diagnoses, and 623 (2.4%) diagnoses of anomaly that was not aneuploidy (including translocations and single chromosome deletions). In comparison with negative test results, pregnancies diagnosed with trisomy were most likely to be terminated (adjusted OR 437.40, 95% CI 348.19–549.46) followed by other aneuploid anomalies (adjusted OR 95.94, 95% CI 69.21–133.01). During the study period, fewer pregnancies that were diagnosed with aneuploidy were terminated, including trisomy diagnoses (adjusted OR 0.44, 95% CI 0.26–0.73). Older women were less likely to terminate (OR 0.35, 95% CI 0.28, 0.42), and parity was also an independent predictor of termination. In keeping with previous findings, while the number of invasive diagnostic tests declined, the proportion of abnormal results increased from 6.09% to 10.88%. Systematic advances in prenatal screening have improved detection rates for aneuploidy. This has been accompanied by a reduction in the rate of termination for aneuploidy. This may reflect societal changes with acceptance of greater diversity, but this is speculation, and further research would be needed to test this

    Legal Responsibility for Public Library Development: United States, Canada, Scandinavia, Nigeria, and South Africa

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    published or submitted for publicatio

    Mass Hysteria or Toxic Fumes? A Case Study for University Administrators

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    The final publication is available at www.degruyter.com. DOI not available.Other research PUBLICATIONS and PAPERS on university students drinking, drug use and health concerns and behaviors can be found at: https://scholarworks.iu.edu/dspace/handle/2022/17130/browse?type=title; https://scholarworks.iu.edu/dspace/handle/2022/17127/browse?type=title and https://scholarworks.iu.edu/dspace/handle/2022/17124/browse?type=title. Further information about the questionnaire, calculations, and the original data base used can be found in the following item records within IUScholarworks repository. Details about the reliability and validity of the SAQ are found at: http://hdl.handle.net/2022/17337; http://hdl.handle.net/2022/17154; http://hdl.handle.net/2022/17181. The classic 1975 copy of the SAQ is found at http://hdl.handle.net/2022/17153. The Health Concern Questionnaire is found at: http://hdl.handle.net/2022/17250. Reliability and validity of this instrument are found at: http://hdl.handle.net/2022/17251. ALL QUESTIONNAIRES developed by Engs are found in the repository at: https://scholarworks.iu.edu/dspace/handle/2022/17141/browse?type=dateissuedThe authors trace the historical background and describe the symptomology relating to mass hysteria and psychogenic illness. After presenting a case study of an incident of such behavior at a mid-western university, they explore the implications for staff training in student service areas
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