The Current State and Necessity of Transformation of the Management System of Educational Establishments in Ukraine at the Local Level

The integration of Ukraine into the European community creates the necessity to carry out scientific research regarding the reformation of public management systems and to introduce principles of state management to management systems. The implementation of administrative reform and the realization of innovative systems of local self-government with elements of state management at local level will foster good conditions for intellectual, professional, and spiritual development in all individuals, and should become a state priority. Therefore, the peculiarities of state management of the educational system at the local level under conditions of education modernization, identification, and the prevention of negative aspects of this process are studied in this article. In regards to state management, the current state of the management system of educational establishments at local level is analyzed, and recommendations concerning changes to this system are proposed according to legislation. It has been found that the reformation of the system of local self-government opens up opportunities for the improvement of the state management model, the implementation of state management principles, and creates good conditions for regional development.Ukrainos integracija į Europos bendruomenę lemia būtinybę atlikti mokslinius tyrimus pertvarkant viešojo valdymo sistemą ir įvesti valstybės valdymo principus valdymo sistemai. Administracinės reformos įgyvendinimas, novatoriškos vietos savivaldos sistemos įgyvendinimas su valstybės valdymo elementais vietos lygiu leis sukurti geras sąlygas kiekvieno žmogaus intelektualiam, profesiniam ir dvasiniam vystymuisi, ir tai turėtų tapti valstybės prioritetu. Todėl darbe nagrinėjami švietimo sistemos valstybinio valdymo vietos lygmeniu ypatumai švietimo modernizavimo sąlygomis ir neigiamų šio proceso aspektų nustatymas bei prevencija. Kalbant apie valstybės valdymą, analizuojama dabartinė švietimo įstaigų valdymo sistema vietos lygmeniu, o straipsnyje pateikiamos rekomendacijos dėl šios sistemos keitimui pagal teisės aktus. Nustatyta, kad vietos savivaldos sistemos pertvarkymas atveria galimybes tobulinti valstybės valdymo modelį, įgyvendinti valstybės valdymo principus ir sudaro geras sąlygas regiono plėtrai

Managing Potential Laboratory Exposure to Ebola Virus by Using a Patient Biocontainment Care Unit1

One-sentence summary for table of contents: Recommendations are needed for management of potential laboratory exposure to a Biosafety Level 4 pathogen

Endothelial dysfunction in patients after COVID-19

Relevance: Over the past two years, the COVID-19 infection has gained unprecedented relevance at the global level. All countries are spending significant resources in the fight against COVID-19 [1 2]. The purpose of the work is to clarify the issue of the state of the kidneys in the distant post-covid period (after 2-3 months), we conducted a study of the kidneys simultaneously with the desquamation of the endothelium, as one of the probable mechanisms of the nephrotic effect of the COVID-19 virus. Materials and methods: 29 people participated in the study. Patients with post-covid syndrome (n=10) were treated on an outpatient basis at the "KNP "Center of primary medical and sanitary (medical and sanitary) care No. 3, Odesa" of the Odesa City Council" in the period from 2020 to 2021. The control group consisted of patients without cardiovascular and endocrine disorders, comparable in terms of gender and age, who were examined in 2018 at the Odesa Regional Clinical Medical Center of the Odesa Regional Council. Endothelial dysfunction "ED" was determined by the intensity of desquamation of the endothelium according to the method of J. Hladovec as modified by M.M. Petryschev. and other. (2001).           Statistical analysis was performed using Status software [https://status-please.herokuapp.com/]. Mean values ​​(M) and its standard deviation (SD) were used to describe quantitative data, and percentages were used for qualitative data. For comparison, data were presented as M and standard error of the mean (SEM). Analysis of normality was performed using the Shapiro-Wilk test. Levene's test was used to assess homogeneity of variances. Differences between groups were determined using Student's t-test and one-way analysis of variance (ANOVA). The relationship and presence of correlation between the studied parameters was determined using the Pearson correlation coefficient (r). The correlation coefficient in the range of 0.5≤|r|<1 indicated a strong correlation relationship, 0.3≤|r|<0.5 – a relationship of medium strength, 0<|r|<0.3 – on a weak correlation. Statistical significance was established only at the level of p < 0.05. Results: 17 men and 12 women aged from 32 to 80 years who suffered from a disease of moderate severity participated in the study. The average age of the group of patients with post-covid syndrome (n=9) is 55.9±14.47 years, the average age of the control group (n=20) is 55.95±14.47 years. There were no complaints from the urinary system in the examined patients. According to blood serum tests, it was established that the creatinine level among patients with post-covid syndrome was on average 113±11.91 μmol/l, the urea level was 8.11±1.2 mmol/l, the GFR level was 55.06±12, 19 ml/min/1.73. m2. In the control group, the numbers were as follows: creatinine level was 73.2±8.5 μmol/l, mean urea level was 4.61 mmol/l, GFR was 94.78±13.76 ml/min/1.73 m2. Conclusions: 2-3 months after the transfer of COVID-19, the examined patients show signs of chronic kidney disease. After a disease with COVID-19, an increase in CEC is detected, which is a manifestation of endothelial dysfunction

Perturbative Effective Field Theory at Finite Density

An accurate description of nuclear matter starting from free-space nuclear forces has been an elusive goal. The complexity of the system makes approximations inevitable, so the challenge is to find a consistent truncation scheme with controlled errors. Nonperturbative effective field theories could be well suited for the task. Perturbative matching in a model calculation is used to explore some of the issues encountered in extending effective field theory techniques to many-body calculations.Comment: 21 pages, 5 figure

Application of ILC super conducting cavities for acceleration of protons

Beam acceleration in the International Linear Collider (ILC) will be provided by 9-cell 1300 MHz superconducting (SC) cavities. The cavities are designed for effective acceleration of charged particles moving with the speed of light and are operated on {pi}-mode to provide maximum accelerating gradient. Significant R&D effort has been devoted to develop ILC SC technology and its RF system which resulted excellent performance of ILC cavities. Therefore, the proposed 8-GeV proton driver in Fermilab is based on ILC cavities above {approx}1.2 GeV. The efficiency of proton beam acceleration by ILC cavities drops fast for lower velocities and it was proposed to develop squeezed ILC-type (S-ILC) cavities operating at 1300 MHz and designed for {beta}{sub G} = 0.81, geometrical beta, to accelerate protons or H{sup -} from {approx}420 MeV to 1.2 GeV. This paper discusses the possibility of avoiding the development of new {beta}{sub G} = 0.81 cavities by operating ILC cavities on 8/9{pi}-mode of standing wave oscillations

The role of neoadjuvant and adjuvant treatment for adenocarcinoma of the upper gastrointestinal tract

Both locally advanced adenocarcinoma of the stomach and gastro-esophageal junction are associated with poor prognosis due to the lack of effective treatment. Recently multimodal treatment consisting of neoadjuvant chemotherapy in combination with radiotherapy is reported to improve survival when compared to surgery alone. Neoadjuvant therapy in these locally advanced tumors allows for early tumor responses and the extent of tumor regression that can be achieved is considered a significant prognostic factor. This, in turn, increases the resectability of these tumors. Also due to the high frequency of lymph node metastasis, patients with locally advanced adenocarcinoma should undergo a D2 lymphadenectomy. Postoperative chemoradiation and perioperative chemotherapy have been studied in gastric adenocarcinomas and showed a survival benefit. However, the surgical techniques used in these trials are no longer considered to be standard by today's surgical practice. In addition, there are no standard recommendations for adjuvant chemotherapy or chemoradiation after R0 resection and adequate lymph node dissection

Sensitivities of the Proton-Nucleus Elastical Scattering Observables of 6He and 8He at Intermediate Energies

We investigate the use of proton-nucleus elastic scattering experiments using secondary beams of 6He and 8He to determine the physical structure of these nuclei. The sensitivity of these experiments to nuclear structure is examined by using four different nuclear structure models with different spatial features using a full-folding optical potential model. The results show that elastic scattering at intermediate energies (<100 MeV per nucleon) is not a good constraint to be used to determine features of structure. Therefore researchers should look elsewhere to put constraints on the ground state wave function of the 6He and 8He nuclei.Comment: To be published in Phys. Rev.

Neutron Production from Feedback Controlled Thermal Cycling of a Pyroelectric Crystal Stack

The LLNL Crystal Driven Neutron Source is operational and has produced record ion currents of {approx}10 nA and neutron output of 1.9 ({+-}0.3) x 10{sup 5} per thermal cycle using a crystal heating rate of 0.2 C/s from 10 C to 110 C. A 3 cm diameter by 1 cm thick LiTaO{sub 3} crystal with a socket secured field emitter tip is thermally cycled with feedback control for ionization and acceleration of deuterons onto a deuterated target to produce D-D fusion neutrons. The entire crystal and temperature system is mounted on a bellows which allows movement of the crystal along the beam axis and is completely contained on a single small vacuum flange. The modular crystal assembly permitted experimental flexibility. Operationally, flashover breakdowns along the side of the crystal and poor emitter tip characteristics can limit the neutron source. The experimental neutron results extend earlier published work by increasing the ion current and pulse length significantly to achieve a factor-of-two higher neutron output per thermal cycle. These findings are reviewed along with details of the instrument