257 research outputs found
Antioxidant activity of hydroxytyrosol in frankfurters enriched with n-3 polyunsaturated fatty acids
8 páginas,6 tablas.The capacity of hydroxytyrosol (HXT) to inhibit lipid oxidation in cooked pork meat batter, oil-in-water
emulsions and potential functional frankfurters formulated with a healthier oil combination (as animal
fat replacer) was studied during chilling storage, and its effect compared with those produced by synthetic
antioxidants (BHA/BHT). Although efficiency varied, HXT was an effective antioxidant during chilling
storage in the three food matrices studied. In general the order of inhibition capacity of HXT against
lipid oxidation (thiobarbituric acid-reactive substances-TBARS) was cooked meat batter > oil-in-water
emulsion > frankfurters, whereas in the case of BHA/BHT (with lower inhibitory activity than HXT) it
was cooked meat batter > oil-in-water emulsion, and there was no antioxidative effect in frankfurters.
Whereas significant correlations were established between lipid oxidation (TBARS) and antioxidative
capacity measured by photochemiluminescence (PCL) in frankfurters supplemented with HXT and
BHA/BHT, no significant correlations were found between ferric reducing/antioxidant power assay (FRAP)
and TBARS and PCL.This research was supported by the projects AGL2008-04892-
CO3-01 and Consolider Ingenio 2010: CARNISENUSA (CSD2007-
00016).Peer reviewe
Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors
BACKGROUND: We aimed to describe the most frequently prescribed initial antiretroviral therapy (ART) regimens in recent years in HIV-positive persons in the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) and to investigate factors associated with the choice of each regimen. METHODS: We analyzed initial ART regimens prescribed in adults participating in CoRIS from 2014 to 2017. Only regimens prescribed in >5% of patients were considered. We used multivariable multinomial regression to estimate Relative Risk Ratios (RRRs) for the association between sociodemographic and clinical characteristics and the choice of the initial regimen. RESULTS: Among 2874 participants, abacavir(ABC)/lamivudine(3TC)/dolutegavir(DTG) was the most frequently prescribed regimen (32.1%), followed by tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC)/elvitegravir(EVG)/cobicistat(COBI) (14.9%), TDF/FTC/rilpivirine (RPV) (14.0%), tenofovir alafenamide (TAF)/FTC/EVG/COBI (13.7%), TDF/FTC+DTG (10.0%), TDF/FTC+darunavir/ritonavir or darunavir/cobicistat (bDRV) (9.8%) and TDF/FTC+raltegravir (RAL) (5.6%). Compared with ABC/3TC/DTG, starting TDF/FTC/RPV was less likely in patients with CD4100.000 copies/mL. TDF/FTC+DTG was more frequent in those with CD4100.000 copies/mL. TDF/FTC+RAL and TDF/FTC+bDRV were also more frequent among patients with CD4<200 cells//muL and with transmission categories other than men who have sex with men. Compared with ABC/3TC/DTG, the prescription of other initial ART regimens decreased from 2014-2015 to 2016-2017 with the exception of TDF/FTC+DTG. Differences in the choice of the initial ART regimen were observed by hospitals' location. CONCLUSIONS: The choice of initial ART regimens is consistent with Spanish guidelines' recommendations, but is also clearly influenced by physician's perception based on patient's clinical and sociodemographic variables and by the prescribing hospital location
Preservation of shelf life of pota and octopus in chilled storage under controlled atmospheres
Whole ungutted pota and octopus were stored in bulk in stainless steel refrigerated containers under controlled atmospheres. In order to evaluate the effectiveness of this treatment, physicochemical tests (pH, trimethylamine nitrogen, total volatile basic nitrogen, 2-thiobarbituric acid) and sensory assessments (inspection) were done. For both pota and octopus, the control lot had the highest physicochemical values and the lowest sensory values, and of the two assayed atmospheres, the 60/15/25% atmosphere (CO2/O2/N2) had the best physicochemical results. pH, trimethylamine nitrogen, and total volatile basic nitrogen levels were lower (P ≤ 0.05) in octopus than in pota, and the inspection results were significantly (P ≤ 0.05) higher. However, the octopus had a higher 2-thiobarbituric acid index than the pota. Therefore, the application of controlled atmospheres on these cephalopods during chilled bulk storage considerably increases their shelf life.Peer Reviewe
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Conferencia impartida por Claudia Ruiz Capillas, el dĂa 20 de marzo en el Museo de la EvoluciĂłn Humana (Burgos)
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