69 research outputs found

    Observer-Based Robust Passive Control for a Class of Uncertain Neutral Systems: An Integral Sliding Mode Approach

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    The problem of integral sliding mode control (ISMC) with passivity is investigated for a class of uncertain neutral systems with time-varying delay (NTSTD) and external disturbance. The system states are unavailable. An ISMC strategy is proposed based on the state estimate. By employing a novel sliding functional, a new sufficient criterion of robust asymptotic stability and passivity for both the error system and the sliding mode (SM) dynamic system is derived via linear matrix inequality (LMI) technique. Then, a SM controller is synthesized to guarantee the reachability of the sliding surface predefined in the state estimate space. Finally, a numerical example shows the feasibility and superiority of the obtained result

    Molecular Characteristics of Staphylococcus aureus From Food Samples and Food Poisoning Outbreaks in Shijiazhuang, China

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    As an opportunistic pathogen worldwide, Staphylococcus aureus can cause food poisoning and human infections. This study investigated the sequence typing, the penicillin (blaZ) and methicillin (mec) resistance profiles of S. aureus from food samples and food poisoning outbreaks in Shijiazhuang City, and the staphylococcal enterotoxin (SE) types of the S. aureus isolates from food poisoning. A total of 138 foodborne S. aureus isolates were distributed into 8 clonal complexes (CCs) and 12 singletons. CC1, CC5, CC8, CC15, CC97, CC59, CC398, CC88, and CC7 were the predominant CCs of foodborne S. aureus isolates. Moreover, CC59, CC15, and CC5 were the most prevalent CCs in food poisoning outbreaks. SEE was the most commonly detected SE in food poisoning isolates. One hundred thirty-three S. aureus isolates harbored the penicillin-resistant gene blaZ, and nine isolates carried the mec gene. The present study further explained the relationship between S. aureus and foods and food poisoning and indicated the potential risk of S. aureus infection

    METI: Deep Profiling of Tumor Ecosystems by Integrating Cell Morphology and Spatial Transcriptomics

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    Recent advances in spatial transcriptomics (ST) techniques provide valuable insights into cellular interactions within the tumor microenvironment (TME). However, most analytical tools lack consideration of histological features and rely on matched single-cell RNA sequencing data, limiting their effectiveness in TME studies. To address this, we introduce the Morphology-Enhanced Spatial Transcriptome Analysis Integrator (METI), an end-to-end framework that maps cancer cells and TME components, stratifies cell types and states, and analyzes cell co-localization. By integrating spatial transcriptomics, cell morphology, and curated gene signatures, METI enhances our understanding of the molecular landscape and cellular interactions within the tissue. We evaluate the performance of METI on ST data generated from various tumor tissues, including gastric, lung, and bladder cancers, as well as premalignant tissues. We also conduct a quantitative comparison of METI with existing clustering and cell deconvolution tools, demonstrating METI\u27s robust and consistent performance

    Effects of Breaking Methods on the Viscosity, Rheological Properties and Nutritional Value of Tomato Paste

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    Ultrasound-assisted processing has potential application advantages as an emerging technology for preparing tomato paste. This work explored the influence of ultrasound break at 22 °C (US-Break-22) and 65 °C (US-Break-65) on the viscosity, rheological properties and nutritional values of newly prepared tomato paste, compared with traditional thermal break at 65 °C (Break-65) and 90 °C (Break-90). Results showed that the US-Break-65 paste had the largest apparent viscosity, yield stress, consistency coefficient, solid-like nature, and large amplitude oscillatory shear behavior, followed by the US-Break-22 paste, Break-90 paste, and Break-65 paste. Based on the results of the pectin-related enzymes, particle size, and serum pectin of the pastes, it was revealed that the above-mentioned properties were mainly determined by the particle size and pectin content in their serum. The level of ascorbic acid followed the order of US-Break-22 paste > US-Break-65 paste > Break-65 paste > Break-90 paste. The level of total carotenoids followed the order of US-Break-22 paste ≈ US-Break-65 paste > Break-90 paste ≈ Break-65 paste. The level of total cis-carotenoids followed the order of US-Break-65 paste > US-Break-22 paste > Break-90 paste > Break-65 paste. The level of phenolics and antioxidant activities followed the same order of US-Break-22 paste > US-Break-65 paste > Break-90 paste > Break-65 paste. Overall, the viscosity, rheological properties and nutritional values of the tomato pastes prepared by US-Break-65 and US-Break-22 were significantly higher than those prepared by Break-65 and Break-90. Therefore, ultrasound assisted processing can prepare high quality tomato paste and can be widely implemented in the tomato paste processing industry

    Manifold-Manifold Distance with Application to Face Recognition Based

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    In this paper, we address the problem of classifying image sets, each of which contains images belonging to the same class but covering large variations in, for instance, viewpoint and illumination. We innovatively formulate the problem as the computation of Manifold-Manifold Distance (MMD), i.e., calculating the distance between nonlinear manifolds each representing one image set. To compute MMD, we also propose a novel manifold learning approach, which expresses a manifold by a collection of local linear models, each depicted by a subspace. MMD is then converted to integrating the distances between pair of subspaces respectively from one of the involved manifolds. The proposed MMD method is evaluated on the task of Face Recognition based on Image Set (FRIS). In FRIS, each known subject is enrolled with a set of facial images and modeled as a gallery manifold, while a testing subject is modeled as a probe manifold, which is then matched against all the gallery manifolds by MMD. Identification is achieved by seeking the minimum MMD. Experimental results on two public face databases, Honda/UCSD and CMU MoBo, demonstrate that the proposed MMD method outperforms the competing methods. 1
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