397 research outputs found
Pregnancy outcome in CharcotβMarieβTooth disease: results of the CMTβNET cohort study in Germany
ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΠΌΠΎΠ΄Π΅ΡΠ½ΠΈΠ·Π°ΡΠΈΠΉ ΡΠΈΠ»ΠΎΠ²ΠΎΠ³ΠΎ ΡΡΠ°Π½ΡΡΠΎΡΠΌΠ°ΡΠΎΡΠ° Ρ ΠΎΠ±ΠΌΠΎΡΠΊΠ°ΠΌΠΈ ΠΈΠ· Π°Π»ΡΠΌΠΈΠ½ΠΈΡ
Metabolic and thermogenic properties of the subcutaneous white adipose tissue of wild and laboratory rodents
For the first time biochemical analysis of inguinal adipose tissue of korean mouse (Apodemus peninsulae) and short-tailed vole (Microtus agrestis) have performed. Expression of uncoupling protein UCP1 in inguinal fat was combined with high metabolic and oxidative activity of this fat depot in wild rodents, in comparison with laboratory mice. Studies of the adipose tissues in animals from natural populations can be useful for the elucidating of the physiological norm of their functioning and for the development of regimes for the prevention and correction of metabolic disorders
Π Π°Π·ΡΠ°Π±ΠΎΡΠΊΠ° ΠΌΠΎΠ΄Π΅Π»ΠΈ Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²Π΅ΡΠΎΡΡΠ½ΠΎΠΉ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Π·Π°Π΄Π°Ρ ΠΏΡΠΎΠ΅ΠΊΡΠ° ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ ΡΠ΅ΡΠ΅ΠΉ
ΠΠ±ΡΠ΅ΠΊΡΠΎΠΌ ΠΏΡΠΎΠ΅ΠΊΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΌΠΎΠ΄Π΅Π»Ρ Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π²Π΅ΡΠΎΡΡΠ½ΠΎΠΉ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Π·Π°Π΄Π°Ρ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ
ΡΠ΅ΡΠ΅ΠΉ ΠΈ Π°Π½Π°Π»ΠΈΠ·Π° ΡΠΈΡΠΊΠΎΠ² ΠΏΠΎ Π·Π°Π΄Π°ΡΠ°ΠΌ. Π ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ» ΠΏΡΠΎΠ²Π΅Π΄ΡΠ½ Π°Π½Π°Π»ΠΈΠ· ΡΠΈΡΠΊΠΎΠ² ΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½ ΡΠ΅ΡΠ²ΠΈΡ Π΄Π»Ρ Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° ΠΏΠΎ Π·Π°Π΄Π°ΡΠ°ΠΌ, Π½Π° ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠΈ ΠΊΠΎΡΠΎΡΠΎΠ³ΠΎ Π±ΡΠ» ΠΏΡΠΎΠΈΠ·Π²Π΅Π΄ΡΠ½ Π²ΡΠ±ΠΎΡ ΠΌΠΎΠ΄Π΅Π»ΠΈ Π΄Π»Ρ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅ΠΉ ΡΠ΅Π°Π»ΠΈΠ·Π°ΡΠΈΠΈ. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ Π±ΡΠ» ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½ Π½Π΅ΠΉΡΠΎΡΠ΅ΡΠ΅Π²ΠΎΠΉ ΠΌΠΎΠ΄Π΅Π»Ρ ΠΊΠΎΡΠΎΡΡΠΉ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ ΡΠ°ΠΊΡΠΎΡΡ ΠΏΠΎ Π·Π°Π΄Π°ΡΠ°ΠΌ ΠΈ ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·ΡΠ²Π°ΡΡ ΡΡΡΠ΄ΠΎΠ·Π°ΡΡΠ°ΡΡ. Π Ρ
ΠΎΠ΄Π΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π°Π½Π°Π»ΠΈΠ·Π° Π±ΡΠ»ΠΈ ΠΏΠΎΠ΄ΠΎΠ±ΡΠ°Π½Ρ ΡΠ°ΠΊΠΈΠ΅ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡ, ΠΏΡΠΈ ΠΊΠΎΡΠΎΡΡΡ
ΠΌΠΎΠ΄Π΅Π»Ρ ΠΏΡΠ΅Π΄ΡΠΊΠ°Π·ΡΠ²Π°Π΅Ρ ΡΡΡΠ΄ΠΎΠ·Π°ΡΡΠ°ΡΡ Ρ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΠΎΡΠ½ΠΎΡΡΠΈ.The object of design and development is a model for determining the most probable duration of tasks using neural networks and risk analysis for tasks. In the course of the research, a risk analysis was carried out and a service was developed for generating risk factors for tasks, on the basis of which a model was selected for further implementation. As a result, a neural network model was proposed that allows you to analyze factors by task and predict labor costs. In the course of the analysis, such parameters were selected at which the model predicts labor costs with high accuracy
Π‘ΠΎΠ·Π΄Π°Π½ΠΈΠ΅ Π»ΠΎΠΊΠ°Π»ΡΠ½ΠΎΠΉ Π±Π°Π·Ρ Π΄Π°Π½Π½ΡΡ Ρ ΠΏΠΎΠΌΠΎΡΡΡ SQLite Π΄Π»Ρ ΠΌΠΎΠ±ΠΈΠ»ΡΠ½ΡΡ ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΠΉ
ΠΡΠΎΠ΅ΠΊΡ ΠΌΠΈΠ½ΠΈ-Π’ΠΠ¦ Π½Π° Π±Π°Π·Π΅ ΠΎΡΠΎΠΏΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΆ/Π΄ ΡΡΠ°Π½ΡΠΈΠΈ ΠΠΎΠ»ΠΎΡΡΡ ΠΈΠ½ΡΠΊΠ°Ρ Π³. ΠΠΎΠ²ΠΎΠΊΡΠ·Π½Π΅ΡΠΊ
ΠΠΈΠΏΠ»ΠΎΠΌΠ½ΡΠΉ ΠΏΡΠΎΠ΅ΠΊΡ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ Π² ΠΎΠ±ΡΠ΅ΠΌΠ΅ 95 ΡΡΡΠ°Π½ΠΈΡ. Π‘ΠΎΠ΄Π΅ΡΠΆΠΈΡ 7 ΡΡ
Π΅ΠΌ, 4 ΠΈΠ»Π»ΡΡΡΡΠ°ΡΠΈΠΈ, 27 ΡΠ°Π±Π»ΠΈΡ, 18 ΠΈΡΡΠΎΡΠ½ΠΈΠΊΠΎΠ², 3 ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΡ, 6 Π». Π³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Π°.
ΠΠ±ΡΠ΅ΠΊΡΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΡΡΡΡ ΡΠ΅ΠΏΠ»ΠΎΠ²ΡΠ΅ Π½Π°Π³ΡΡΠ·ΠΊΠΈ ΡΡΡΠ΅ΡΡΠ²ΡΡΡΠ΅ΠΉ ΠΊΠΎΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΈ ΡΠ΅Π»Π΅ΡΠΎΠΎΠ±ΡΠ°Π·Π½ΠΎΡΡΡ Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠΈ ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠ½Π΅ΡΠ³ΠΈΠΈ Π΄Π»Ρ ΠΏΠΎΠΊΡΡΡΠΈΡ ΠΏΠΎΡΡΠ΅Π±Π½ΠΎΡΡΠ΅ΠΉ.
Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ β ΠΏΡΠΎΠ΅ΠΊΡ ΡΠ΅ΠΊΠΎΠ½ΡΡΡΡΠΊΡΠΈΠΈ ΠΎΡΠΎΠΏΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΆ/Π΄ ΠΠΎΠ»ΠΎΡΡΡ
ΠΈΠ½ΡΠΊΠ°Ρ Π³.ΠΠΎΠ²ΠΎΠΊΡΠ·Π½Π΅ΡΠΊ Ρ ΡΠ΅Π»ΡΡ ΡΠΎΠ·Π΄Π°Π½ΠΈΡ ΠΌΠΈΠ½ΠΈ-Π’ΠΠ¦ ΠΈ ΠΏΠ΅ΡΠ΅Ρ
ΠΎΠ΄Π° Π½Π° ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ΅ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄ΡΡΠ²ΠΎ ΡΠ΅ΠΏΠ»ΠΎΠ²ΠΎΠΉ ΠΈ ΡΠ»Π΅ΠΊΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΠ½Π΅ΡΠ³ΠΈΠΈ.
Π ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΡΡ Π²ΡΠ±ΠΎΡ ΡΠ΅ΠΏΠ»ΠΎΠ²ΠΎΠΉ ΡΡ
Π΅ΠΌΡ ΠΌΠΈΠ½ΠΈ-Π’ΠΠ¦ ΠΈ Π΅Ρ ΠΏΡΠΎΠ΅ΠΊΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Π½Π° Π±Π°Π·Π΅ ΠΎΡΠΎΠΏΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΡΠ΅Π»ΡΠ½ΠΎΠΉ.
Π Π΅Π·ΡΠ»ΡΡΠ°Ρ ΡΠ°ΡΡΠ΅ΡΠ° ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΈ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΡΡ ΡΠ΅Π»Π΅ΡΠΎΠΎΠ±ΡΠ°Π·Π½ΠΎΡΡΡ ΡΠΊΡΠΏΠ»ΡΠ°ΡΠ°ΡΠΈΠΈ Π³Π°Π·ΠΎΠΏΠΎΡΡΠ½Π΅Π²ΠΎΠΉ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠΈ ΠΈ Π²Π½Π΅Π΄ΡΠ΅Π½ΠΈΠ΅ Π³Π°Π·ΠΈΡΠΈΠΊΠ°ΡΠΎΡΠ° Π² ΡΡ
Π΅ΠΌΠ΅ Π’ΠΠ¦.The degree project carried out in a volume of 95 pages. 7 contains diagrams, illustrations, 4, 27 tables, 18 sources three applications 6L. graphic material.
The object of research is the thermal load of the existing boiler and feasibility of generating electricity to cover the needs.
The purpose of the work - the project of reconstruction of the heating boiler w / d Polosukhinskaya Novokuznetsk to create a mini-CHP and the transition to the combined production of heat and electricity.
The study was conducted selection of the thermal circuit CHP and its design based on the heating boiler.
The result of calculation shows the cost-effectiveness and technological feasibility of operating a gas piston installation and implementation of the scheme the gasifier in CHP
Π Π°Π·Π²ΠΈΡΠΈΠ΅ ΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π° Π² ΠΌΠ°Π»ΠΎΠΌ Π±ΠΈΠ·Π½Π΅ΡΠ΅ (Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ Π§Π°ΡΡΠ½ΠΎΠ³ΠΎ ΠΠ°Π»ΠΎΠ³ΠΎ ΠΡΠ΅Π΄ΠΏΡΠΈΡΡΠΈΡ Β«ΠΡΠ»Π°Π½ΡΠ°Β» Π³ΠΎΡΠΎΠ΄Π° ΠΠ»ΠΌΠ°Π»ΡΠΊΠ° Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΈ Π£Π·Π±Π΅ΠΊΠΈΡΡΠ°Π½
ΠΠ±ΡΠ΅ΠΊΡΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: -Π²ΡΡΡΡΠΏΠ°Π΅Ρ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ ΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π° Π² ΠΌΠ°Π»ΠΎΠΌ Π±ΠΈΠ·Π½Π΅ΡΠ΅.
Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: -Π°Π½Π°Π»ΠΈΠ· ΡΠΈΡΡΠ΅ΠΌΡ ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ ΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π° Π² ΠΌΠ°Π»ΠΎΠΌ Π±ΠΈΠ·Π½Π΅ΡΠ΅ (Π½Π° ΠΏΡΠΈΠΌΠ΅ΡΠ΅ Π§Π°ΡΡΠ½ΠΎΠ³ΠΎ ΠΠ°Π»ΠΎΠ³ΠΎ ΠΡΠ΅Π΄ΠΏΡΠΈΡΡΠΈΡ "ΠΡΠ»Π°Π½ΡΠ°") ΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ° ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΉ ΠΏΠΎ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΡ Π΅Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ.
Π ΠΏΡΠΎΡΠ΅ΡΡΠ΅ ΠΏΡΠΎΠ΄Π΅Π»Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ ΠΏΠΎ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π°Π½Π°Π»ΠΈΠ·Π° ΡΠΈΡΡΠ΅ΠΌΡ, Π±ΡΠ»ΠΎ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΡΠΎΡΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅.
Π Π΅Π·ΡΠ»ΡΡΠ°Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ - Π²ΡΡΠ²Π»Π΅Π½ΠΈΠ΅ ΠΎΡΠ½ΠΎΠ²Π½ΡΡ
ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΠΉ ΠΏΠΎ ΡΡΠΎΠ²Π΅ΡΡΠ΅Π½ΡΡΠ²ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΈ ΠΎΠ±ΡΡΠ΅Π½ΠΈΡ ΠΏΠ΅ΡΡΠΎΠ½Π°Π»Π°.The object of the research: -supports the development and training of staff in small business.
The purpose of the study: -analysis of the system of training and staff development in small businesses (for example, Private Small Enterprise "Atlanta") and development of recommendations for improving its effectiveness.
In the process of the work done on the study of system analysis, a sociological study.
The result of this study was to identify key recommendations to improve the program development and staff training
Microstructure and properties of 308LSI steel obtained by deposition of metal wire
Shaped metal deposition (SMD) is a relatively new technology of additive manufacturing, which creates near-net shaped components by joining metallic materials by melting the area of a welding joint in high vacuum in the range from 10-3 to 10-6 mbar. In the present study, the main mechanical properties including micro-hardness and tensile properties were investigated. Single bead walls were deposited. Test pieces were machined from the deposited walls according to the National standard of Russia Federation for the mechanical tests. The tensile properties also showed dependence on the direction of the test carried out. All the examined tensile properties of the as deposited samples are close-matched properties of the as cast material
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